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May - June 2006 A propósito de um caso de imunodeficiência comum variável – Revisão das...
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Vol. 12. Issue 3.
Pages 293-301 (May - June 2006)
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Vol. 12. Issue 3.
Pages 293-301 (May - June 2006)
DOI: 10.1016/S2173-5115(06)70404-3
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A propósito de um caso de imunodeficiência comum variável – Revisão das hipogamaglobulinemias
About a case of common variable immunodeficiency – Revision of hypogammaglobulinemias
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Alexandra Lopes*,
, Fernando Barata**, Ricardo Conceição***, Rui Pato****
* Internato Complementar de Medicina Interna, Serviço de Medicina do Centro Hospitalar de Coimbra
** Assistente Hospitalar Graduado de Pneumologia, Serviço de Pneumologia do Centro Hospitalar de Coimbra
*** Serviço de Medicina do Centro Hospitalar de Coimbra, Serviço de Pneumologia do Centro Hospitalar de Coimbra
**** Serviço de Pneumologia do Centro Hospitalar de Coimbra, Serviço de Pneumologia do Centro Hospitalar de Coimbra
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Resumo

A imunodeficiência comum variável é uma imunodeficiência primária caracterizada por distúrbios imunológicos heterogéneos, de etiologia desconhecida. As suas manifestações clínicas incluem infecções recorrentes, doenças auto-imunes, hiperplasia linfóide, doenças granulomatosas e neoplasias; pode aparecer em doentes com deficiência de IgA. Os autores apresentam o caso clínico de doente com imunodeficiência comum variável e história de infecções respiratórias de repetição desde os 9 meses, associadas ao aparecimento de bronquiectasias.

Palavras-chave:
Imunodeficiência comum variável
Abstract

Common variable immunodeficiency is a primary immune deficiency characterized by heterogeneous immunologic disorders of unknown etiology. Its clinical manifestations include recurrent infections, autoimmune diseases, lymphoid hyperplasia, granulomatous diseases and malignancy. It can appear in patients with immunoglobulin A deficiency. The authors report the clinical case of a patient with common variable immunodeficiency and history of respiratory infections from the age of 9 months old, associated with the appearing of bronchiectasis.

Key-words:
Common variable immunodeficiency
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