array:24 [
  "pii" => "S2173511506704274"
  "issn" => "21735115"
  "doi" => "10.1016/S2173-5115(06)70427-4"
  "estado" => "S300"
  "fechaPublicacion" => "2006-11-01"
  "aid" => "70427"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2006"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "fla"
  "cita" => "Rev Port Pneumol. 2006;12:659-67"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2794
    "formatos" => array:3 [
      "EPUB" => 246
      "HTML" => 1552
      "PDF" => 996
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173511506704286"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70428-6"
    "estado" => "S300"
    "fechaPublicacion" => "2006-11-01"
    "aid" => "70428"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Pneumol. 2006;12:669-82"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2594
      "formatos" => array:3 [
        "EPUB" => 212
        "HTML" => 1393
        "PDF" => 989
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "The evaluation of neopterin and antioxidants in long lasting asthma"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "669"
          "paginaFinal" => "682"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Determinação da neopterina e de defesas antioxidantes na asma de evolução arrastada"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A. Mota Pinto, A. Todo-Bom, S. Vale Pereira, V. Alves, M. Santos Rosa, Doutora Anabela Mota Pinto, Celso Chieira, Doutor Manuel Santos Rosa"
          "autores" => array:8 [
            0 => array:2 [
              "nombre" => "A."
              "apellidos" => "Mota Pinto"
            ]
            1 => array:2 [
              "nombre" => "A."
              "apellidos" => "Todo-Bom"
            ]
            2 => array:2 [
              "nombre" => "S."
              "apellidos" => "Vale Pereira"
            ]
            3 => array:2 [
              "nombre" => "V."
              "apellidos" => "Alves"
            ]
            4 => array:2 [
              "nombre" => "M."
              "apellidos" => "Santos Rosa"
            ]
            5 => array:2 [
              "nombre" => "Doutora Anabela"
              "apellidos" => "Mota Pinto"
            ]
            6 => array:2 [
              "nombre" => "Celso"
              "apellidos" => "Chieira"
            ]
            7 => array:2 [
              "nombre" => "Doutor Manuel"
              "apellidos" => "Santos Rosa"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704286?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000006/v1_201305151431/S2173511506704286/v1_201305151431/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173511506704262"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70426-2"
    "estado" => "S300"
    "fechaPublicacion" => "2006-11-01"
    "aid" => "70426"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Pneumol. 2006;12:637-58"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3119
      "formatos" => array:3 [
        "EPUB" => 215
        "HTML" => 1866
        "PDF" => 1038
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Non invasive evaluation of central venous pressure using echocardiography in the intensive care – Specific features of patients with right ventricular enlargement and chronic exacerbated pulmonary disease"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "637"
          "paginaFinal" => "658"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Avaliação não invasiva da pressão venosa central por ecocardiografia em cuidados intensivos – Particularidades nos doentes com dilatação do ventrículo direito e exacerbação de doença pulmonar crónica"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Paulo Marcelino, Alexandra Borba, Ana Paula Fernandes, Susan Marum, Nuno Germano, Mário G. Lopes"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Paulo"
              "apellidos" => "Marcelino"
            ]
            1 => array:2 [
              "nombre" => "Alexandra"
              "apellidos" => "Borba"
            ]
            2 => array:2 [
              "nombre" => "Ana Paula"
              "apellidos" => "Fernandes"
            ]
            3 => array:2 [
              "nombre" => "Susan"
              "apellidos" => "Marum"
            ]
            4 => array:2 [
              "nombre" => "Nuno"
              "apellidos" => "Germano"
            ]
            5 => array:2 [
              "nombre" => "Mário G."
              "apellidos" => "Lopes"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704262?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000006/v1_201305151431/S2173511506704262/v1_201305151431/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "titulo" => "Comparison between total lung capacity and residual volume values obtained by pletysmography and single breath methods with methane"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "659"
        "paginaFinal" => "667"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Ricardo Marques Dias, Fernando Hauaji Chacur, Sonia Regina da Silva Carvalho, André Luís Mancini, Geraldo A. Capuchino"
        "autores" => array:5 [
          0 => array:4 [
            "nombre" => "Ricardo"
            "apellidos" => "Marques Dias"
            "email" => array:1 [
              0 => "pfr@procardiaco.com.br"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Fernando"
            "apellidos" => "Hauaji Chacur"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">2</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Sonia Regina"
            "apellidos" => "da Silva Carvalho"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">3</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Andr&#233;"
            "apellidos" => "Lu&#237;s Mancini"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">4</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
          4 => array:4 [
            "nombre" => "Geraldo A&#46;"
            "apellidos" => "Capuchino"
            "sufijo" => "Jr"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">4</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:4 [
          0 => array:3 [
            "entidad" => "Professor Titular da Disciplina de Pneumologia da UNIRIO&#44; HU Gaffr&#233;e e Guinle &#47; <span class="elsevierStyleItalic">Titular Professor&#44; Pulmonology&#44; UNIRIO&#44; Gaffr&#233;e e Guinle University Hospital</span>"
            "etiqueta" => "<span class="elsevierStyleSup">1</span>"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Respons&#225;vel pelo Servi&#231;o de Provas de Fun&#231;&#227;o Respirat&#243;ria do Pr&#243;cardiaco &#47; <span class="elsevierStyleItalic">Head of Pr&#243;cardiaco Respiratory Function Unit</span>"
            "etiqueta" => "<span class="elsevierStyleSup">2</span>"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Profa Adjunta da Disciplina Cardiopulmonar da UNIRIO&#44; Respons&#225;vel pelo Ambulat&#243;rio de Asma &#47; <span class="elsevierStyleItalic">Associate Professor&#44; Cardio-pulmonary&#44; UNIRIO&#44; Head of Asthma Out-Patients</span>"
            "etiqueta" => "<span class="elsevierStyleSup">3</span>"
            "identificador" => "aff0015"
          ]
          3 => array:3 [
            "entidad" => "Bolseiro de Inicia&#231;&#227;o Cient&#237;fica da UNIRIO &#47; <span class="elsevierStyleItalic">Scholarship holder&#44; Science Initiation&#44; UNIRIO</span>"
            "etiqueta" => "<span class="elsevierStyleSup">4</span>"
            "identificador" => "aff0020"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Correspondence to&#47;Correspond&#234;ncia&#58; Laborat&#243;rio de Fun&#231;&#227;o Pulmonar &#8211; Hospital Pr&#243;cardiaco&#46; Rua Dona Mariana 219 CEP 22280-020 Botafogo RJ Rio de Janeiro Brasil&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Compara&#231;&#227;o dos valores da capacidade pulmonar total e do volume residual obtidos pelas t&#233;cnicas pletismogr&#225;fica e de respira&#231;&#227;o &#250;nica com metano"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2006-04-27"
    "fechaAceptado" => "2006-07-21"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key-words"
          "identificador" => "xpalclavsec158909"
          "palabras" => array:5 [
            0 => "Whole body pletysmography"
            1 => "pulmonary diffusion test &#40;DLco&#41;"
            2 => "pulmonary volumes"
            3 => "pulmonary function tests"
            4 => "asthma"
          ]
        ]
      ]
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec158908"
          "palabras" => array:5 [
            0 => "Pletismografia de corpo inteiro"
            1 => "teste de difus&#227;o &#40;DLCO&#41;"
            2 => "determina&#231;&#227;o dos volumes pulmonares"
            3 => "testes de fun&#231;&#227;o pulmonar"
            4 => "asma"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">We analyzed pulmonary function tests of twenty asthmatic patients from Gaffr&#233;e e Guinle University Hospital&#44; classified according to Brazilian Guidelines for Asthma &#40;2002&#41;&#44; similar to GINA&#44; into mild persistent or moderate &#40;9&#41; or severe &#40;11&#41; asthma&#46; We obtained parameters from spirometry&#44; plethysmograph&#40;PL&#41; and single breath technique for diffusion capacity &#40;SB&#41;&#44; with methane&#46; Total lung capacity and residual volume were called TLC<span class="elsevierStyleInf">PL</span> and RV<span class="elsevierStyleInf">PL</span> when measured by pletysmography and TLC<span class="elsevierStyleInf">SB</span> and RV<span class="elsevierStyleInf">SB</span> when determined by single breath test&#46; There were 13 women and 7 men with mean age of 47&#46;6 years&#46; The pulmonary dysfunction degree to FEV1&#47;FVC was 58&#46;8&#37; with CI95&#61;53&#46;9 to 63&#46;6&#46; The mean values in litres for TLC<span class="elsevierStyleInf">PL</span> &#40;5&#46;94&#41; and RV<span class="elsevierStyleInf">PL</span> &#40;2&#46;55&#41; were significantly higher than for TLCSB &#40;4&#46;73&#41; and RVSB &#40;1&#46;66&#41;&#46; Multiple regression equations were determined for TLC<span class="elsevierStyleInf">PL</span> e RV<span class="elsevierStyleInf">PL</span> using only single breath values&#44; TLC<span class="elsevierStyleInf">SB</span> or RV<span class="elsevierStyleInf">SB</span>&#44; and spirographic parameters&#44; with significant regression coefficients&#46; However&#44; the inclusion of spirometric parameters&#44; except for FVC&#44; did not improve the predicted capacity for the equations&#46; Considering only the TLCSB&#44; r<span class="elsevierStyleSup">2</span>&#61;0&#46;79&#44; the equation is&#58; TLC<span class="elsevierStyleInf">PL</span>&#61;&#40;TLC<span class="elsevierStyleInf">SB</span>&#42;1&#46;025&#41;&#43;1&#46;088&#44; with EPE&#61;0&#46;64&#46; The regression for RV<span class="elsevierStyleInf">PL</span>&#44; r<span class="elsevierStyleSup">2</span>&#61;0&#46;23&#44; is&#58; RV<span class="elsevierStyleInf">PL</span>&#61;&#40;RV<span class="elsevierStyleInf">SB</span>&#42;0&#46;9268&#41;&#43;1&#46;012&#46; The results obtained after bronchodilation with 400 mcg of salbutamol did not improve the regression&#46; We concluded that the SB technique did not obtain the same results as pletysmography for TLC and RV&#44; but for TLC this difference can be predicted&#46;</p>"
      ]
      "pt" => array:2 [
        "titulo" => "Resumo"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Foram analisados exames de fun&#231;&#227;o pulmonar de 20 asm&#225;ticos&#44; em acompanhamento no HU Gaffr&#233;e Guinle&#44; classificados&#44; segundo o Consenso Brasileiro &#40;2002&#41;&#44; em asma leve persistente ou moderada &#40;9&#41; e grave &#40;11&#41;&#46; Foram obtidos os valores dos par&#226;metros da espirografia&#44; da pletismografia e da t&#233;cnica de respira&#231;&#227;o &#250;nica&#44; com metano&#44; para a medida da difus&#227;o pulmonar &#40;DLco&#41;&#46; Assim&#44; a capacidade pulmonar total e o volume residual&#44; quando medidos pela pletismografia&#44; foram designados&#44; respectivamente&#44; CPT<span class="elsevierStyleInf">PL</span> e VR<span class="elsevierStyleInf">PL</span>&#46; Da mesma forma&#44; quando determinados pela t&#233;cnica de respira&#231;&#227;o &#250;nica&#44; CPT<span class="elsevierStyleInf">SB</span> e VR<span class="elsevierStyleInf">SB</span>&#46; A amostra foi constitu&#237;da por 13 mulheres e 7 homens&#44; sendo a m&#233;dia de idade de 47&#44;6 anos&#46; A intensidade da disfun&#231;&#227;o&#44; medida pela rela&#231;&#227;o VEMS&#47;CVF foi de 58&#44;8&#37;&#44; com IC95 de 53&#44;9 a 63&#44;6&#46; Os valores de CPT<span class="elsevierStyleInf">PL</span> &#40;5&#44;94&#41; e VR<span class="elsevierStyleInf">PL</span> &#40;2&#44;55&#41;&#44; expressos em litros e pela m&#233;dia&#44; foram significativamente maiores do que os de CPT<span class="elsevierStyleInf">SB</span> &#40;4&#44;73&#41; e VR<span class="elsevierStyleInf">SB</span> &#40;1&#44;66&#41;&#46; Foram determinadas equa&#231;&#245;es de regress&#227;o m&#250;ltipla&#44; para previs&#227;o dos valores de CPT<span class="elsevierStyleInf">PL</span> e VR<span class="elsevierStyleInf">PL</span>&#44; utilizando os valores de CPT<span class="elsevierStyleInf">SB</span>&#44; VR<span class="elsevierStyleInf">SB</span> e dos par&#226;metros espirogr&#225;ficos&#44; com coeficientes de regress&#227;o significativos&#46; Contudo&#44; a inclus&#227;o dos par&#226;metros espirogr&#225;ficos&#44; excepto por CVF&#44; n&#227;o melhorou a capacidade de previs&#227;o das equa&#231;&#245;es&#46; Considerando apenas a CPT<span class="elsevierStyleInf">SB</span>&#44; r<span class="elsevierStyleSup">2</span>&#61;0&#44;79&#44; a equa&#231;&#227;o &#233;&#58; CPT<span class="elsevierStyleInf">PL</span>&#61;&#40;CPT<span class="elsevierStyleInf">SB</span>&#42;1&#44;025&#41;&#43;1&#44;088&#44; com EP&#61;0&#44;64&#46; A regress&#227;o para VR<span class="elsevierStyleInf">PL</span>&#44; com r<span class="elsevierStyleSup">2</span>&#61;0&#44;23&#44; &#233;&#58; VR<span class="elsevierStyleInf">PL</span>&#61;&#40;VR<span class="elsevierStyleInf">SB</span>&#42;0&#44;9268&#41;&#43;1&#44;012&#46; Os exames realizados ap&#243;s a broncodilata&#231;&#227;o&#44; com 400mcg de salbutamol&#44; n&#227;o melhoraram as equa&#231;&#245;es&#46; Conclu&#237;mos que a t&#233;cnica de SB n&#227;o d&#225; resultados iguais aos da pletismografia para CPT e VR&#59; contudo&#44; para a CPT&#44; esta diferen&#231;a pode ser prevista&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara">Trabalho realizado no HU Gaffr&#233;e e Guinle e no Hospital Pr&#243;cardiaco &#47; Work undertaken at Gaffr&#233;e e Guinle University Hospital and at the Pr&#243;cardiaco Hospital&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliography&#47;Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:15 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology standardization project&#58; recommended standardization procedure for pulmonary function testing"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "American Thoracic Society"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/arrd.1978.118.1.55"
                      "Revista" => array:7 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1978"
                        "volumen" => "118"
                        "numero" => "Suppl 2"
                        "paginaInicial" => "55"
                        "paginaFinal" => "88"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/677558"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "III Consenso Brasileiro no Manejo da Asma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Sociedade Brasileira de Pneumologia e Tisiologia"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Pneumol"
                        "fecha" => "2002"
                        "volumen" => "28"
                        "numero" => "supl 1"
                        "paginaInicial" => "S1"
                        "paginaFinal" => "S28"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Global Initiatve for Asthma&#46; Workshop Report&#44; Global Strategy for Asthma Management and Prevention&#46; Update 2005&#46; <a class="elsevierStyleInterRef" href="http://www.ginasthma.com/">www&#46;ginasthma&#46;com&#47;</a>"
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "I Consenso Brasileiro sobre Espirometria"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Sociedade Brasileira de Pneumologia e Tisiologia"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Pneumol"
                        "fecha" => "1996"
                        "volumen" => "22"
                        "numero" => "3"
                        "paginaInicial" => "105"
                        "paginaFinal" => "164"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diretrizes para Testes de Fun&#231;&#227;o Pulmonar"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Sociedade Brasileira de Pneumologia e&#44; Tisiologia"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Pneumol"
                        "fecha" => "2002"
                        "volumen" => "28"
                        "numero" => "supl 3"
                        "paginaInicial" => "S1"
                        "paginaFinal" => "S238"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "ATS&#47;ERS Task Force&#58; Standardization of Lung Function Testing&#58; Standardization of&#44; spirometry"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09031936.05.00034805"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2005"
                        "volumen" => "26"
                        "paginaInicial" => "319"
                        "paginaFinal" => "338"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16055882"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "ATS&#47;ERS Task Force&#58; Standardization of Lung Function Testing&#58; Standardization of the measurement of lung&#44; volumes"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09031936.05.00035005"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2005"
                        "volumen" => "26"
                        "paginaInicial" => "511"
                        "paginaFinal" => "522"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16135736"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Standardization of the single-breath determination of carbon monoxide uptake in the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "ATS&#47;ERS Task Force&#58; Standardization of Lung Function&#44; Testing"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09031936.05.00034905"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2005"
                        "volumen" => "26"
                        "paginaInicial" => "720"
                        "paginaFinal" => "735"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16204605"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Interpretative Strategies for Lung Function Tests"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "ATS&#47;ERS Task Force&#58; Standardization of Lung Function Testing"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09031936.05.00035205"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2005"
                        "volumen" => "26"
                        "paginaInicial" => "948"
                        "paginaFinal" => "968"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16264058"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Changes in the normal maximal expiratory flow volume curve with growth and aging"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46;J&#46; Knudson"
                            1 => "M&#46;D&#46; Lebowitz"
                            2 => "C&#46;J&#46; Holberg"
                            3 => "B&#46; Burrows"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1983"
                        "volumen" => "127"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Standardized single breath normal values for carbon monoxide diffusing capacity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;O&#46; Crapo"
                            1 => "A&#46;H&#46; Morris"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/arrd.1981.123.2.185"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1981"
                        "volumen" => "123"
                        "paginaInicial" => "185"
                        "paginaFinal" => "189"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7235357"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lung volumes in healthy nonsmoking adults"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;O&#46; Crapo"
                            1 => "A&#46;H&#46; Morris"
                            2 => "P&#46;D&#46; Clayton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Bull Eur Physiophatol Respir"
                        "fecha" => "1982"
                        "volumen" => "18"
                        "paginaInicial" => "419"
                        "paginaFinal" => "425"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "GraphPad InStat version 3&#46;01&#44; Copyright 1992&#8211;1998 GraphPad Software Inc&#44; San Diego California USA&#44; <a class="elsevierStyleInterRef" href="http://www.graphpad.com/">www&#46;graphpad&#46;com</a>"
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "MedCalc Version 8&#46;1&#46;1&#46;0 &#8211; &#169; 1993&#8211;2005 Frank Schoonjans&#44; <a class="elsevierStyleInterRef" href="http://www.medcalc.be/">http&#58;&#47;&#47;www&#46;medcalc&#46;be&#47;</a>"
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Correlation of a single-breath helium lung volumes in patients with air flow obstruction"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "N&#46;M&#46; Punjabi"
                            1 => "B&#46;A&#46; David Shade"
                            2 => "R&#46;A&#46; Wise"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1998"
                        "volumen" => "114"
                        "paginaInicial" => "907"
                        "paginaFinal" => "918"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9743183"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735115/0000001200000006/v1_201305151431/S2173511506704274/v1_201305151431/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9552"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Original Article&#47;Artigo Original"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001200000006/v1_201305151431/S2173511506704274/v1_201305151431/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704274?idApp=UINPBA00004E"
]
Share
Journal Information
Vol. 12. Issue 6.
Pages 659-667 (November - December 2006)
Share
Share
Download PDF
More article options
Vol. 12. Issue 6.
Pages 659-667 (November - December 2006)
Full text access
Comparison between total lung capacity and residual volume values obtained by pletysmography and single breath methods with methane
Comparação dos valores da capacidade pulmonar total e do volume residual obtidos pelas técnicas pletismográfica e de respiração única com metano
Visits
933
Ricardo Marques Dias1,
Corresponding author
pfr@procardiaco.com.br

Correspondence to/Correspondência: Laboratório de Função Pulmonar – Hospital Prócardiaco. Rua Dona Mariana 219 CEP 22280-020 Botafogo RJ Rio de Janeiro Brasil.
, Fernando Hauaji Chacur2, Sonia Regina da Silva Carvalho3, André Luís Mancini4, Geraldo A. Capuchino Jr4
1 Professor Titular da Disciplina de Pneumologia da UNIRIO, HU Gaffrée e Guinle / Titular Professor, Pulmonology, UNIRIO, Gaffrée e Guinle University Hospital
2 Responsável pelo Serviço de Provas de Função Respiratória do Prócardiaco / Head of Prócardiaco Respiratory Function Unit
3 Profa Adjunta da Disciplina Cardiopulmonar da UNIRIO, Responsável pelo Ambulatório de Asma / Associate Professor, Cardio-pulmonary, UNIRIO, Head of Asthma Out-Patients
4 Bolseiro de Iniciação Científica da UNIRIO / Scholarship holder, Science Initiation, UNIRIO
This item has received
Article information
Abstract

We analyzed pulmonary function tests of twenty asthmatic patients from Gaffrée e Guinle University Hospital, classified according to Brazilian Guidelines for Asthma (2002), similar to GINA, into mild persistent or moderate (9) or severe (11) asthma. We obtained parameters from spirometry, plethysmograph(PL) and single breath technique for diffusion capacity (SB), with methane. Total lung capacity and residual volume were called TLCPL and RVPL when measured by pletysmography and TLCSB and RVSB when determined by single breath test. There were 13 women and 7 men with mean age of 47.6 years. The pulmonary dysfunction degree to FEV1/FVC was 58.8% with CI95=53.9 to 63.6. The mean values in litres for TLCPL (5.94) and RVPL (2.55) were significantly higher than for TLCSB (4.73) and RVSB (1.66). Multiple regression equations were determined for TLCPL e RVPL using only single breath values, TLCSB or RVSB, and spirographic parameters, with significant regression coefficients. However, the inclusion of spirometric parameters, except for FVC, did not improve the predicted capacity for the equations. Considering only the TLCSB, r2=0.79, the equation is: TLCPL=(TLCSB*1.025)+1.088, with EPE=0.64. The regression for RVPL, r2=0.23, is: RVPL=(RVSB*0.9268)+1.012. The results obtained after bronchodilation with 400 mcg of salbutamol did not improve the regression. We concluded that the SB technique did not obtain the same results as pletysmography for TLC and RV, but for TLC this difference can be predicted.

Key-words:
Whole body pletysmography
pulmonary diffusion test (DLco)
pulmonary volumes
pulmonary function tests
asthma
Resumo

Foram analisados exames de função pulmonar de 20 asmáticos, em acompanhamento no HU Gaffrée Guinle, classificados, segundo o Consenso Brasileiro (2002), em asma leve persistente ou moderada (9) e grave (11). Foram obtidos os valores dos parâmetros da espirografia, da pletismografia e da técnica de respiração única, com metano, para a medida da difusão pulmonar (DLco). Assim, a capacidade pulmonar total e o volume residual, quando medidos pela pletismografia, foram designados, respectivamente, CPTPL e VRPL. Da mesma forma, quando determinados pela técnica de respiração única, CPTSB e VRSB. A amostra foi constituída por 13 mulheres e 7 homens, sendo a média de idade de 47,6 anos. A intensidade da disfunção, medida pela relação VEMS/CVF foi de 58,8%, com IC95 de 53,9 a 63,6. Os valores de CPTPL (5,94) e VRPL (2,55), expressos em litros e pela média, foram significativamente maiores do que os de CPTSB (4,73) e VRSB (1,66). Foram determinadas equações de regressão múltipla, para previsão dos valores de CPTPL e VRPL, utilizando os valores de CPTSB, VRSB e dos parâmetros espirográficos, com coeficientes de regressão significativos. Contudo, a inclusão dos parâmetros espirográficos, excepto por CVF, não melhorou a capacidade de previsão das equações. Considerando apenas a CPTSB, r2=0,79, a equação é: CPTPL=(CPTSB*1,025)+1,088, com EP=0,64. A regressão para VRPL, com r2=0,23, é: VRPL=(VRSB*0,9268)+1,012. Os exames realizados após a broncodilatação, com 400mcg de salbutamol, não melhoraram as equações. Concluímos que a técnica de SB não dá resultados iguais aos da pletismografia para CPT e VR; contudo, para a CPT, esta diferença pode ser prevista.

Palavras-chave:
Pletismografia de corpo inteiro
teste de difusão (DLCO)
determinação dos volumes pulmonares
testes de função pulmonar
asma
Full text is only aviable in PDF
Bibliography/Bibliografia
[1.]
American Thoracic Society.
Epidemiology standardization project: recommended standardization procedure for pulmonary function testing.
Am Rev Respir Dis, 118 (1978), pp. 55-88
[2.]
Sociedade Brasileira de Pneumologia e Tisiologia.
III Consenso Brasileiro no Manejo da Asma.
J Pneumol, 28 (2002), pp. S1-S28
[3.]
Global Initiatve for Asthma. Workshop Report, Global Strategy for Asthma Management and Prevention. Update 2005. www.ginasthma.com/
[4.]
Sociedade Brasileira de Pneumologia e Tisiologia.
I Consenso Brasileiro sobre Espirometria.
J Pneumol, 22 (1996), pp. 105-164
[5.]
Sociedade Brasileira de Pneumologia e, Tisiologia.
Diretrizes para Testes de Função Pulmonar.
J Pneumol, 28 (2002), pp. S1-S238
[6.]
ATS/ERS Task Force: Standardization of Lung Function Testing: Standardization of, spirometry.
Eur Respir J, 26 (2005), pp. 319-338
[7.]
ATS/ERS Task Force: Standardization of Lung Function Testing: Standardization of the measurement of lung, volumes.
Eur Respir J, 26 (2005), pp. 511-522
[8.]
ATS/ERS Task Force: Standardization of Lung Function, Testing.
Standardization of the single-breath determination of carbon monoxide uptake in the lung.
Eur Respir J, 26 (2005), pp. 720-735
[9.]
ATS/ERS Task Force: Standardization of Lung Function Testing.
Interpretative Strategies for Lung Function Tests.
Eur Respir J, 26 (2005), pp. 948-968
[10.]
R.J. Knudson, M.D. Lebowitz, C.J. Holberg, B. Burrows.
Changes in the normal maximal expiratory flow volume curve with growth and aging.
Am Rev Respir Dis, 127 (1983),
[11.]
R.O. Crapo, A.H. Morris.
Standardized single breath normal values for carbon monoxide diffusing capacity.
Am Rev Respir Dis, 123 (1981), pp. 185-189
[12.]
R.O. Crapo, A.H. Morris, P.D. Clayton.
Lung volumes in healthy nonsmoking adults.
Bull Eur Physiophatol Respir, 18 (1982), pp. 419-425
[13.]
GraphPad InStat version 3.01, Copyright 1992–1998 GraphPad Software Inc, San Diego California USA, www.graphpad.com
[14.]
MedCalc Version 8.1.1.0 – © 1993–2005 Frank Schoonjans, http://www.medcalc.be/
[15.]
N.M. Punjabi, B.A. David Shade, R.A. Wise.
Correlation of a single-breath helium lung volumes in patients with air flow obstruction.
Chest, 114 (1998), pp. 907-918

Trabalho realizado no HU Gaffrée e Guinle e no Hospital Prócardiaco / Work undertaken at Gaffrée e Guinle University Hospital and at the Prócardiaco Hospital.

Copyright © 2006. Sociedade Portuguesa de Pneumologia
Download PDF
Pulmonology
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?