Corresponding author/Correspondência: Rua Barão da Torre 388/104 – CEP 22411-000, Ipanema – Rio de Janeiro – RJ - Brasil.
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Regina da Silva de Carvalho" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Geraldo Andrade" "apellidos" => "Capuchinho-Júnior" "email" => array:1 [ 0 => "jrcapuchinho@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] ] ] 1 => array:4 [ "nombre" => "Ricardo Marques" "apellidos" => "Dias" "email" => array:1 [ 0 => "dias.ricardomarques@gmail.com" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0015" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0030" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 2 => array:4 [ "nombre" => "Sônia Regina" "apellidos" => "da Silva de Carvalho" "email" => array:1 [ 0 => "csvmarlin@ig.com.br" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0025" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Académico da Escola de Medicina e Cirurgia da Universidade Federal do Estado do Rio de Janeiro (UniRio), bolseiro do Programa de Iniciação Científica da UNIRIO (IC/ UniRio) / <span class="elsevierStyleItalic">Scholarship holder, UNIRIO Scientific Initiation Programme (IC/UniRio)</span>" "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Professor Titular de Pneumologia da UniRio, Doutor em Medicina (Pneumologia). Líder do Grupo de Pesquisa “Pneumologia-UNIRIO” / <span class="elsevierStyleItalic">Titular Professor, Pulmonology UniRio, MD (Pulmonology). UniRio-Pulmonology research team leader</span>" "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0015" ] 2 => array:3 [ "entidad" => "Professora Adjunta da UniRio, Mestre em Medicina (Pneumologia) / <span class="elsevierStyleItalic">Assistant Professor, UniRio, MSc Medicine (Pulmonology)</span>" "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0025" ] 3 => array:3 [ "entidad" => "Hospital Universitário Gaffrée e Guinle (HUGG) – Unidade Cardiopulmonar Chefe do Serviço" "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0030" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author/Correspondência: Rua Barão da Torre 388/104 – CEP 22411-000, Ipanema – Rio de Janeiro – RJ - Brasil." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Efeitos do salbutamol e do formoterol sobre pressão arterial, frequência cardíaca e saturação de oxigénio em asmáticos, durante uma hora" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-08-15" "fechaAceptado" => "2008-01-07" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec159571" "palabras" => array:5 [ 0 => "Asthma" 1 => "bronchodilator agents/adverse effects" 2 => "heart rate" 3 => "blood pressure" 4 => "oxygen saturation" ] ] ] "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec159570" "palabras" => array:5 [ 0 => "Asma" 1 => "broncodilatadores/efeitos adversos" 2 => "frequência cardíaca" 3 => "pressão arterial sistémica" 4 => "saturação de oxigénio" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Aim</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To analyse systolic (SBP) and diastolic blood pressure (DBP), partial oxygen saturation (SpO<span class="elsevierStyleInf">2</span>) and heart rate (HR) disorders for an hour after short and long acting ß<span class="elsevierStyleInf">2</span>-agonists.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Twenty-four severe persistent asthma Pulmonology outpatients at Hospital Universitario Gaffree e Guinle were selected. SBP, DBP, SpO<span class="elsevierStyleInf">2</span> and HR values were determined before and after 400<span class="elsevierStyleHsp" style=""></span>μg of salbutamol and 12<span class="elsevierStyleHsp" style=""></span>μg of formoterol, on different days, with a minimum interval of 24 hours.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">All patients showed ventilatory obstruction, as seen by a reduced FEV1/FVC ratio. There was no statistical SBP/DBP/HR difference after bronchodilator agents, but SpO<span class="elsevierStyleInf">2</span> increased with salbutamol.</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">A standard dose of salbutamol and formoterol does not cause haemodynamic disorder.</p>" ] "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span class="elsevierStyleSectionTitle">Objectivo</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Analisar os possíveis efeitos do uso de β-2-agonistas, de curta e longa duração, nas pressões arteriais sistólica (PAS) e diastólica (PAD), na saturação parcial de oxigénio (SpO<span class="elsevierStyleInf">2</span>) e na frequência cardíaca (FC), durante o período de uma hora.</p> <span class="elsevierStyleSectionTitle">Material e métodos</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Vinte e quatro doentes com asma persistente grave, em tratamento no ambulatório de Pneumologia do Hospital Universitário Gaffrée e Guinle, foram seleccionados para um ensaio clínico sequencial e cruzado. Os valores da PAS, PAD, SpO<span class="elsevierStyleInf">2</span> e FC foram registados antes e após o uso de broncodilatadores, salbutamol 400<span class="elsevierStyleHsp" style=""></span>μg e formoterol 12<span class="elsevierStyleHsp" style=""></span>μg, em dias diferentes, com intervalo mínimo de 24 horas.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Todos os doentes apresentaram distúrbio ventilatório obstrutivo, identificado pela redução da relação entre o volume expiratório forçado no primeiro segundo (VEMS) e a capacidade vital forçada (CVF). Após o uso de substância broncodilatadora, não houve variação significativa nas PAS e PAD, nem na FC; porém, a SpO<span class="elsevierStyleInf">2</span> aumentou com o uso de salbutamol.</p> <span class="elsevierStyleSectionTitle">Conclusão</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Não foram observadas alterações hemodinâmicas significativas após o uso de salbutamol e formoterol nas doses preconizadas.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliography/Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:14 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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Year/Month | Html | Total | |
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