Avaliação dos resultados nos ensaios clínicos na DPOC: Da função pulmonar aos marcadores biológicos
M. Cazzola, W. MacNee, F.J. Martinez, K.F. Rabe
On behalf of the ATS/ERS TASK Force on outcomes of COPD. Eur Respir J 2008; 31:416-468
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"apellidos" => "Rabe" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "On behalf of the ATS/ERS TASK Force on outcomes of COPD. Eur Respir J 2008; 31:416-468" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "tieneResumen" => true "resumen" => array:1 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">As sociedades científicas respiratórias europeia e americana (ERS e ATS) constituíram um grupo de trabalho sobre a “Avaliação dos resultados nos ensaios clínicos na DPOC: da função pulmonar aos marcadores biológicos” para informar a comunidade de investigadores em DPOC sobre o possível uso e limitações dos resultados obtidos e marcadores usados actualmente na avaliação do impacto da terapêutica farmacológica. Com base na revisão da literatura, este documento aborda diferentes secções que avaliam marcadores e resultados específicos: função pulmonar; resultados centrados no doente; exacerbações; nortalidade; impacto social e económico; exames de imagem; marcadores não pulmonares; mínima diferença clinicamente significativa; marcadores biológicos.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Workshop Report (Updated 2007). <a class="elsevierStyleInterRef" href="http://www.goldcopd.org/">www.goldcopd.org</a>. 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ISSN: 21735115Original language: Portuguese
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