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Vidal, M. Rafael, L. Boto, J. Rios, C. Camilo, F. Abecasis, M. Vieira" "autores" => array:7 [ 0 => array:2 [ "nombre" => "R.L." "apellidos" => "Vidal" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Rafael" ] 2 => array:2 [ "nombre" => "L." "apellidos" => "Boto" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Rios" ] 4 => array:2 [ "nombre" => "C." "apellidos" => "Camilo" ] 5 => array:2 [ "nombre" => "F." "apellidos" => "Abecasis" ] 6 => array:2 [ "nombre" => "M." "apellidos" => "Vieira" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511516301300?idApp=UINPBA00004E" "url" => "/21735115/0000002300000002/v1_201703040135/S2173511516301300/v1_201703040135/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2173511516301415" "issn" => "21735115" "doi" => "10.1016/j.rppnen.2016.10.005" "estado" => "S300" "fechaPublicacion" => "2017-03-01" "aid" => "1208" "copyright" => "Sociedade Portuguesa de Pneumologia" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "cor" "cita" => "Rev Port Pneumol. 2017;23:109-10" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1438 "formatos" => array:3 [ "EPUB" => 205 "HTML" => 622 "PDF" => 611 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Research letter</span>" "titulo" => "Cystic adenomatoid pulmonary malformation in adults: A retrospective study in a tertiary university hospital" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "109" "paginaFinal" => "110" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1370 "Ancho" => 900 "Tamanyo" => 271267 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Type 0 CAM. (A) Irregular bronchial-like structures lined by pseudostratified ciliated columnar epithelium (PAS, ×400). (B) Columnar epithelium surrounded by prominent loose mesenchymal tissue (Vim, ×400).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.C. Duarte, P.G. Ferreira, T.M. Alfaro, L. Carvalho, A.J. Ferreira" "autores" => array:5 [ 0 => array:2 [ "nombre" => "J.C." "apellidos" => "Duarte" ] 1 => array:2 [ "nombre" => "P.G." "apellidos" => "Ferreira" ] 2 => array:2 [ "nombre" => "T.M." "apellidos" => "Alfaro" ] 3 => array:2 [ "nombre" => "L." "apellidos" => "Carvalho" ] 4 => array:2 [ "nombre" => "A.J." "apellidos" => "Ferreira" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511516301415?idApp=UINPBA00004E" "url" => "/21735115/0000002300000002/v1_201703040135/S2173511516301415/v1_201703040135/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Idiopathic pleuroparenchymal fibroelastosis with suggestive biopsy of pulmonary carcinoma – Case report" "tieneTextoCompleto" => true "saludo" => "To the Editor," "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "111" "paginaFinal" => "113" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "R.C. Oliveira, T. Nogueira, L. Carvalho" "autores" => array:3 [ 0 => array:4 [ "nombre" => "R.C." "apellidos" => "Oliveira" "email" => array:1 [ 0 => "ruipedrocoliveira@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "T." "apellidos" => "Nogueira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "L." "apellidos" => "Carvalho" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Pathology Department, Coimbra University Hospital, Portugal" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Thoracic Surgery Department, Coimbra University Hospital, Portugal" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 706 "Ancho" => 900 "Tamanyo" => 118596 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Computed tomography (CT) showing solitary pulmonary lesion in the upper right lobe. The lesion has irregular boundaries and a caveated component is exhibited.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is an uncommon and recently defined condition characterized by fibrosis and thickening of dense and subpleural lung parenchyma, mainly in the upper lobes,<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">1</span></a> presenting with clinical course similar to chronic fibrosing interstitial pneumonias.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">2</span></a> Thickening of visceral pleura combined with collagenic and intra-alveolar fibrosis and septal elastosis in abrupt transition to remaining lung parenchyma<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">3</span></a> compose an overlapping pattern with other interstitial pneumonias, where bad prognosis, different therapeutic options and knowledge of this entity are essential in medical practice.</p><p id="par0010" class="elsevierStylePara elsevierViewall">An 82-years-old male was referred to the Pulmonology Department due to right thoracic pain and episode of haemoptysis. A computed tomography (CT) scan showed a solitary pulmonary lesion in the upper right lobe (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>), with 18-fludeoxyglucose uptake on positron emission tomography-computed tomography.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">A transthoracic needle biopsy was performed and lung parenchyma with mild septa enlargement due to fibrosis was observed with one edge exhibiting a group of atypical cells in acinar arrangement together with large eosinophilic cells with hyperchromatic nuclei. Immunohistochemistry studies were positivity for cytokeratin 7 (SP52), cytokeratin 5/6 (D5/16B4), vimentin (V9) and thyroid transcription factor (TTF1, SP141) – all from Ventana, AZ-USA; Periodic acid-Schiff (PAS) was also positive. The diagnosis of probable adenosquamous carcinoma was proposed, taking into consideration the available representative factors.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Additional study of the patient was made: atrial fibrillation, smoking habits and dyslipidaemia were his pathological conditions. Physical evaluation, blood tests and respiratory function tests were normal (forced expiratory volume<span class="elsevierStyleHsp" style=""></span>−<span class="elsevierStyleHsp" style=""></span>FEV1<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>96.7%). An upper right lobectomy and mediastinal lymphadenectomy was performed.</p><p id="par0025" class="elsevierStylePara elsevierViewall">We received a RULobectomy of 133<span class="elsevierStyleHsp" style=""></span>g weight gross and measuring 20<span class="elsevierStyleHsp" style=""></span>cm<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>10.5<span class="elsevierStyleHsp" style=""></span>cm<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>3.5<span class="elsevierStyleHsp" style=""></span>cm with areas of irregular visceral pleura that on cut surface revealed pleural thickening and subpleural dense tissue with a nodule measuring 3<span class="elsevierStyleHsp" style=""></span>cm<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>2.5<span class="elsevierStyleHsp" style=""></span>cm<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>3<span class="elsevierStyleHsp" style=""></span>cm; a caveated lesion with 1.5<span class="elsevierStyleHsp" style=""></span>cm was also detected, surrounded by dense lung parenchyma.</p><p id="par0030" class="elsevierStylePara elsevierViewall">Microscopically there was pleural thickening, with collagenous fibrosis (MT), and subpleural architectural distortion with elastosis and intra alveolar fibrosis (MT, EVG), with curled, short and randomly oriented elastic fibres. There were alveolar spaces and bronchioles imprisoned by the lesion, with bronchial associated lymphoid tissue hyperplasia and marked reactive changes in the epithelium (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). The caveated lesion showed giant multinucleated cells, foreign body type, surrounded by fibroelastic band. In the periphery of the lesion, there was organizing pneumonia with inflammatory myofibroblastic polyps. An abrupt transition to the remaining lung parenchyma was registered, which showed emphysema and constrictive bronchiolitis.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">The patient was revaluated three weeks after surgery. A chest X-ray showed minimal pneumothorax that disappeared in two weeks, without need for chest drainage.</p><p id="par0040" class="elsevierStylePara elsevierViewall">IPPFE is an exceptional clinicopathological syndrome with its own radiological and histological features; there are fewer than 100 cases reported in the literature, first referred in 1992 by Amitani et al.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">4</span></a> and later characterized by Frank et al. in 2004<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">5</span></a>; nowadays it is classified as a rare idiopathic interstitial pneumonia (IIP) by the updated American Thoracic Society/European Respiratory Society (ATS/ERS) classification.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">1</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Clinically IPPFE does not show age or gender predilection and is not related to smoking, it presents normally with exertional dyspnoea and dry cough. Body weight loss may be registered and chest pain can occur as a consequence of pneumothorax.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">2</span></a> Patients with IPPEF exhibit disease progression in 60%, with death from disease occurring in 40%.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">1</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">Classical histology presents upper zone fibrosis of the visceral pleura, homogenous and prominent subpleural fibrosis and alveolar septal elastosis, with preservation of pulmonary parenchyma away from pleura and abrupt transition of affected to normal tissue; however these findings may not appear or be absent in small biopsies.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">3</span></a> In our case, classical histological elements were present, but the entrapped respiratory spaces with epithelial cells exhibiting marked reactive cellular atypia provided a diagnostic pitfall in transthoracic biopsy.</p><p id="par0055" class="elsevierStylePara elsevierViewall">Radiological patterns may contribute to definite diagnosis with upper lobe pleural thickening and subpleural fibrosis and less/absent lower lobe involvement on high resolution computed tomography (HRCT),<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">2,3</span></a> without reference to defined nodular pattern as seen in this case.</p><p id="par0060" class="elsevierStylePara elsevierViewall">The main differential diagnoses are connective tissue diseases, asbestosis, fibrosing sarcoidosis, radiation/drug induced diseases and normal interstitial pneumonia, the latter mainly in biopsies<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">6</span></a>; the absence of occupational exposure to dusts and the histological combination of intra-alveolar fibrosis and septal elastosis should favour IPPFE diagnosis.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">3</span></a></p><p id="par0065" class="elsevierStylePara elsevierViewall">Up till now therapeutic schemes have not shown efficacy in IPPFE, as it is refractory to steroids/immunosuppressive agents, but survival may reach 11 years in lung-transplantation associated cases; supporting care may be useful and oxygen support is mandatory in advanced stages as well as infection control.<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">2,7</span></a></p><p id="par0070" class="elsevierStylePara elsevierViewall">IPPFE is a distinct and well characterized entity with aggressive and rapidly progressive course and poor prognosis. The intense fibroelastosis may be associated with prominent inflammatory and reactive changes, making the differential diagnosis with other IIPs challenging and occasionally mimicking oncologic diseases, especially in small biopsies, with actual case reflecting a possible nodular pattern.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0075" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflicts of interest" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 706 "Ancho" => 900 "Tamanyo" => 118596 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Computed tomography (CT) showing solitary pulmonary lesion in the upper right lobe. The lesion has irregular boundaries and a caveated component is exhibited.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1124 "Ancho" => 1500 "Tamanyo" => 514552 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Dense pleural and subpleural fibrosis with abrupt transition to non-affected pulmonary parenchyma (A, H&E 20×); subpleural elastosis and intra alveolar fibrosis with alveolar spaces and bronchioles imprisoned by the lesion, with bronchial associated lymphoid tissue hyperplasia (B, H&E 40×); diffuse and severe elastosis with curled, short and randomly oriented elastic fibres (C and D, EVG 100× and 200×).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:7 [ 0 => array:3 [ "identificador" => "bib0040" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "An official American Thoracic Society/European Respiratory Society statement: update of the international multidisciplinary classification of the idiopathic interstitial pneumonias" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "W.D. Travis" 1 => "U. Costabel" 2 => "D. Hansell" 3 => "T. King" 4 => "D. Lynch" 5 => "A. Nicholson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/rccm.201308-1483ST" "Revista" => array:4 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2013" "volumen" => "188" "paginaInicial" => "733e48" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0045" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pleuroparenchymal fibroelastosis: its clinical characteristic" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "K. Watanabe" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2174/1573398X0904140129125307" "Revista" => array:5 [ "tituloSerie" => "Curr Resp Med Rev" "fecha" => "2013" "volumen" => "9" "paginaInicial" => "229" "paginaFinal" => "237" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0050" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pleuroparenchymal fibroelastosis: its pathological characteristics" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.H. von der Thüsen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2174/1573398X113096660025" "Revista" => array:5 [ "tituloSerie" => "Curr Resp Med Rev" "fecha" => "2013" "volumen" => "9" "paginaInicial" => "238" "paginaFinal" => "247" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0055" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Idiopathic pulmonary upper lobe fibrosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R. Amitani" 1 => "A. Niimi" 2 => "F. Kuze" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Kokyu" "fecha" => "1992" "volumen" => "11" "paginaInicial" => "693" "paginaFinal" => "699" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0060" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Idiopathic pleuroparenchymal fibroelastosis: description of a novel clinicopathological entity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S. Frankel" 1 => "D. Cool" 2 => "D. Lynch" 3 => "K. Brown" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.126.6.2007" "Revista" => array:4 [ "tituloSerie" => "Chest" "fecha" => "2004" "volumen" => "126" "paginaInicial" => "2007e13" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0065" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Idiopathic pleuroparenchymal fibroelastosis: an unrecognized or misdiagnosed entity?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.D. Becker" 1 => "J. Gil" 2 => "M.L. Padilla" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/modpathol.2008.56" "Revista" => array:6 [ "tituloSerie" => "Mod Pathol" "fecha" => "2008" "volumen" => "21" "paginaInicial" => "784" "paginaFinal" => "787" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18408658" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0070" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pleuroparenchymal fibroelastosis: a pattern of chronic lung injury" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.N. Rosebaum" 1 => "Y.M. Butt" 2 => "K.A. Johnson" 3 => "K. Meyer" 4 => "K. Batra" 5 => "J.P. Kanne" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.humpath.2014.10.007" "Revista" => array:6 [ "tituloSerie" => "Hum Pathol" "fecha" => "2015" "volumen" => "46" "paginaInicial" => "137" "paginaFinal" => "146" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25454481" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735115/0000002300000002/v1_201703040135/S2173511516301397/v1_201703040135/en/main.assets" "Apartado" => array:4 [ "identificador" => "20584" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735115/0000002300000002/v1_201703040135/S2173511516301397/v1_201703040135/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511516301397?idApp=UINPBA00004E" ]
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