Letter to the Editor
COVID-19 does not stop good practice in smoking cessation: Safe use of CO analyzer for smokers in the Covid era
Read
6906
Timeswas read the article
2339
Total PDF
4567
Total HTML
Share statistics
array:23 [ "pii" => "S2531043720302087" "issn" => "25310437" "doi" => "10.1016/j.pulmoe.2020.08.008" "estado" => "S300" "fechaPublicacion" => "2021-03-01" "aid" => "1541" "copyrightAnyo" => "2020" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "cor" "cita" => "Pulmonol. 2021;27:173-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "itemSiguiente" => array:19 [ "pii" => "S2531043720302063" "issn" => "25310437" "doi" => "10.1016/j.pulmoe.2020.08.007" "estado" => "S300" "fechaPublicacion" => "2021-03-01" "aid" => "1538" "copyright" => "Sociedade Portuguesa de Pneumologia" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "cor" "cita" => "Pulmonol. 2021;27:175-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:9 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Results from phase II, open-label study of anti-tumoral activity of first-line erlotinib in advanced/metastatic NSCLC patients with EGFR activating mutations, in Portugal: The MuTAR study" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "175" "paginaFinal" => "177" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "F. Barata, H. Queiroga, E. Teixeira, T. Almodovar, M. Soares, B. Parente, J.C. Mellidez, P. Alves, A. Antunes" "autores" => array:9 [ 0 => array:2 [ "nombre" => "F." "apellidos" => "Barata" ] 1 => array:2 [ "nombre" => "H." "apellidos" => "Queiroga" ] 2 => array:2 [ "nombre" => "E." "apellidos" => "Teixeira" ] 3 => array:2 [ "nombre" => "T." "apellidos" => "Almodovar" ] 4 => array:2 [ "nombre" => "M." "apellidos" => "Soares" ] 5 => array:2 [ "nombre" => "B." "apellidos" => "Parente" ] 6 => array:2 [ "nombre" => "J.C." "apellidos" => "Mellidez" ] 7 => array:2 [ "nombre" => "P." "apellidos" => "Alves" ] 8 => array:2 [ "nombre" => "A." "apellidos" => "Antunes" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2531043720302063?idApp=UINPBA00004E" "url" => "/25310437/0000002700000002/v2_202105110755/S2531043720302063/v2_202105110755/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2531043720302269" "issn" => "25310437" "doi" => "10.1016/j.pulmoe.2020.10.009" "estado" => "S300" "fechaPublicacion" => "2021-03-01" "aid" => "1556" "copyright" => "Sociedade Portuguesa de Pneumologia" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "cor" "cita" => "Pulmonol. 2021;27:171-3" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Wearing of medical mask over the high-flow nasal cannula for safer oxygen therapy in the COVID-19 era" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "171" "paginaFinal" => "173" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 737 "Ancho" => 1500 "Tamanyo" => 224994 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Photographs of droplet dispersion after cough when not utilizing (A) and utilizing supplemental oxygen via nasal cannula (B) and HFNC (C) and with an appropriately placed medical mask when not utilizing (D) and utilizing supplemental oxygen delivered by nasal cannula (E) and HFNC (F).</p> <p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">HFNC = high-flow nasal cannula.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "S. Hamada, N. Tanabe, H. Inoue, T. Hirai" "autores" => array:4 [ 0 => array:2 [ "nombre" => "S." "apellidos" => "Hamada" ] 1 => array:2 [ "nombre" => "N." "apellidos" => "Tanabe" ] 2 => array:2 [ "nombre" => "H." "apellidos" => "Inoue" ] 3 => array:2 [ "nombre" => "T." "apellidos" => "Hirai" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2531043720302269?idApp=UINPBA00004E" "url" => "/25310437/0000002700000002/v2_202105110755/S2531043720302269/v2_202105110755/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "COVID-19 does not stop good practice in smoking cessation: Safe use of CO analyzer for smokers in the Covid era" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "173" "paginaFinal" => "174" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "E. Munarini, C. Veronese, A.C. Ogliari, F. Allegri, M.G. Bolchi, R. Boffi" "autores" => array:6 [ 0 => array:3 [ "nombre" => "E." "apellidos" => "Munarini" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 1 => array:4 [ "nombre" => "C." "apellidos" => "Veronese" "email" => array:1 [ 0 => "chiara.veronese@istitutotumori.mi.it" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 2 => array:3 [ "nombre" => "A.C." "apellidos" => "Ogliari" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "F." "apellidos" => "Allegri" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "M.G." "apellidos" => "Bolchi" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 5 => array:3 [ "nombre" => "R." "apellidos" => "Boffi" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Antismoking Center, Pulmonology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133 Milan, Italy" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Health & Safety Protection Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133 Milan, Italy" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author at: Pulmonology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133 Milan, Italy." ] ] ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1752 "Ancho" => 1500 "Tamanyo" => 133782 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Smokerlyzer’s components: electronic device (a); original fitting (b); disposable mouthpieces (c); fitting specially created (d); disposable spirometry mouthpieces (e).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Smoking has been proven to be an important risk factor for disease severity and worse outcomes in Covid-19, the disease caused by SARS-CoV-2.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The World Health Organization (WHO) recommends not smoking in order to reduce the risk of harm caused by the disease and warns against reports that tobacco or nicotine could benefit Covid-19 as they do not provide sufficient evidence for this statement.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> In our practice at the Antismoking Center of the National Cancer Institute of Milan, the smoker’s assessment has proved particularly useful, in particular, for this purpose, we use carbon monoxide (CO) measure in the exhaled breath.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Starting from June 2020 it was possible, keeping the distance between patients and the use of personal protection devices, to resume the activity of the antismoking center, but the Covid-19 situation has posed non-emergency labs with the question of how to proceed with clinical tests safely while avoiding virus transmission among patients<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a>; so, we addressed the problem of safe CO measurement.</p><p id="par0020" class="elsevierStylePara elsevierViewall">The level of carboxyhemoglobin in the blood can be determined by measuring the exhaled CO through an instrument that provides the CO value in parts per million (ppm). This type of measurement is then configured as an extremely useful tool in smoking cessation assessment, to enhance motivation to quit and for follow-up of smoking cessation programs.</p><p id="par0025" class="elsevierStylePara elsevierViewall">One of the major company for CO analyzers is Bedfont Scientific Ltd with its main product “Smokerlyzer™”, a portable instrument with research and education aims. The model we have available in our antismoking centre is a Micro<span class="elsevierStyleSup">+</span> Smokerlyzer™ model purchased in 2012. It is composed of the electronic device (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>a), the fitting provided with an antibacterial filter (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>b) which lasts 30 days and the disposable mouthpieces (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>c). For the latest models Bedfont has produced disposable antibacterial filters, but our model is not compatible.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">To safely use the CO analyzer, we thought of substituting the fitting with an antibacterial filter with a new one, specially created (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>d). This fitting, designed with the help of our clinical engineering department, was made of a plastic polymer and printed via a 3D printer. The size of the fitting (section and length) was calculated to make minimum modifications in order not to change significantly the flow rate and the volume of air entering the device; in this way it is possible to avoid alterations related to the detection and calibration of the instrument. It does not contain any filters and it can be washed and disinfected after each use. The fitting has been molded to allow the attachment of disposable mouthpieces that we usually use for the execution of spirometries (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>e). This mouthpiece contains an electrostatic and certified mechanical filter that removes bacteria and viruses at an efficiency rate of >99%, thus reducing risks of cross contamination during testing. Through this solution we can guarantee the use of a single filter for each patient.</p><p id="par0035" class="elsevierStylePara elsevierViewall">The safety of this measurement must be guaranteed not only for patients but also healthcare professionals. The use of appropriate personal protective equipment (PPE) is of pivotal importance for the healthcare workers involved in the care of patients with viral infections, such as the current pandemic, Covid-19.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> In collaboration with Health and Safety Protection Unit, considering that this procedure provides for the emission of exhaled breath, we have reviewed it: workers must carry out the procedure with Covid-19 personal PPE and, as further precaution, the patient is asked to plug his or her nose with disposable forceps so that there is no exhalation from the nasal cavities during the procedure.</p><p id="par0040" class="elsevierStylePara elsevierViewall">Due to the risk of Covid-19 transmission, it was impossible for us to test the CO analyzer for correct measurement of exhaled CO for smokers with and without modified fitting, but during the first period of the modified device use, we verified that the detector has not undergone alterations in the measurement of the CO concentration. In fact, we used the device during our checks among smoking patients and we detected values ​​compatible with the self-reported smoking status.</p><p id="par0045" class="elsevierStylePara elsevierViewall">The completely new situation that arose during the period of the Covid-19 pandemic, characterized by social isolation, physical distancing, possible loss of employment and prolonged lockdown, is highly stressful and therefore predisposing people to find refuge in addictive substance, and among these, tobacco.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">Therefore, smokers and ex-smokers are at greater risk of worsening their health condition by smoke dependence due to the pandemic; furthermore, smoking does not only constitute individual damage: the lockdown has forced many people to stay at home, increasing indoor smoking and therefore the possibility of exposing family and neighbors to secondhand smoke<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a>; in addition, cigarette smoke has been identified as a possible vehicle for the Covid-19 virus as droplets are more easily released into the environment while smoking.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> In addition some studies<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> have even indicated that the pandemic has increased the possibility of people wanting to quit smoking.</p><p id="par0055" class="elsevierStylePara elsevierViewall">All these considerations suggest the importance of promoting smoking cessation during the Covid-19 pandemic. In the future it will be necessary not to interrupt the antismoking services, including the measurement of CO safe for patients.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0060" class="elsevierStylePara elsevierViewall">The authors have no Conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflicts of interest" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2020-08-06" "multimedia" => array:1 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1752 "Ancho" => 1500 "Tamanyo" => 133782 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Smokerlyzer’s components: electronic device (a); original fitting (b); disposable mouthpieces (c); fitting specially created (d); disposable spirometry mouthpieces (e).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:7 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "COVID-19 and smoking: a systematic review of the evidence" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C.I. Vardavas" 1 => "K. Nikitara" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.18332/tid/119324" "Revista" => array:5 [ "tituloSerie" => "Tob Induc Dis" "fecha" => "2020" "volumen" => "18" "paginaInicial" => "20" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32206052" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "WHO statement: Tobacco use and COVID-19" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "WHO" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "WWW" => array:2 [ "link" => "https://www.who.int/news-room/detail/11-05-2020-who-statement-tobacco-use-and-covid-19" "fecha" => "2020" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sleep labs, lung function tests and COVID-19 pandemic – only emergencies allowed!" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M. Drummond" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.pulmoe.2020.04.002" "Revista" => array:6 [ "tituloSerie" => "Pulmonology" "fecha" => "2020" "volumen" => "26" "paginaInicial" => "244" "paginaFinal" => "245" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32371053" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Medical masks and respirators for the protection of healthcare workers from SARS-CoV-2 and other viruses" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Ippolito" 1 => "F. Vitale" 2 => "G. Accurso" 3 => "P. Iozzo" 4 => "C. Gregoretti" 5 => "A. Giarratano" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.pulmoe.2020.04.009" "Revista" => array:7 [ "tituloSerie" => "Pulmonology" "fecha" => "2020" "volumen" => "26" "numero" => "4" "paginaInicial" => "204" "paginaFinal" => "212" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32362505" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Change in tobacco and electronic cigarette use and motivation to quit in response to COVID-19" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E.M. Klemperer" 1 => "J.C. West" 2 => "C. Peasley-Miklus" 3 => "A.C. Villanti" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/ntr/ntaa072" "Revista" => array:5 [ "tituloSerie" => "Nicotine Tob Res" "fecha" => "2020" "numero" => "April" "paginaInicial" => "ntaa072" "itemHostRev" => array:3 [ "pii" => "S1386505618300108" "estado" => "S300" "issn" => "13865056" ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "COVID-19 lockdown and the tobacco product ban in South Africa" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C.O. Egbe" 1 => "S.P. Ngobese" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.18332/tid/120938" "Revista" => array:5 [ "tituloSerie" => "Tob Induc Dis" "fecha" => "2020" "volumen" => "18" "paginaInicial" => "39" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32395100" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tobacco smoking a potential risk factor in transmission of COVID-19 infection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "N. Ahmed" 1 => "A. Maqsood" 2 => "T. Abduljabbar" 3 => "F. Vohra" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.12669/pjms.36.COVID19-S4.2739" "Revista" => array:6 [ "tituloSerie" => "Pak J Med Sci" "fecha" => "2020" "volumen" => "36" "numero" => "COVID19-S4" "paginaInicial" => "S104" "paginaFinal" => "S107" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/25310437/0000002700000002/v2_202105110755/S2531043720302087/v2_202105110755/en/main.assets" "Apartado" => array:4 [ "identificador" => "72880" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/25310437/0000002700000002/v2_202105110755/S2531043720302087/v2_202105110755/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2531043720302087?idApp=UINPBA00004E" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 7 | 3 | 10 |
| 2024 October | 44 | 56 | 100 |
| 2024 September | 56 | 39 | 95 |
| 2024 August | 61 | 41 | 102 |
| 2024 July | 63 | 36 | 99 |
| 2024 June | 63 | 32 | 95 |
| 2024 May | 60 | 43 | 103 |
| 2024 April | 78 | 38 | 116 |
| 2024 March | 59 | 27 | 86 |
| 2024 February | 56 | 28 | 84 |
| 2024 January | 59 | 36 | 95 |
| 2023 December | 45 | 24 | 69 |
| 2023 November | 92 | 60 | 152 |
| 2023 October | 51 | 43 | 94 |
| 2023 September | 55 | 42 | 97 |
| 2023 August | 49 | 15 | 64 |
| 2023 July | 46 | 50 | 96 |
| 2023 June | 45 | 24 | 69 |
| 2023 May | 66 | 44 | 110 |
| 2023 April | 37 | 18 | 55 |
| 2023 March | 81 | 39 | 120 |
| 2023 February | 56 | 38 | 94 |
| 2023 January | 64 | 18 | 82 |
| 2022 December | 72 | 33 | 105 |
| 2022 November | 83 | 38 | 121 |
| 2022 October | 110 | 42 | 152 |
| 2022 September | 111 | 59 | 170 |
| 2022 August | 106 | 41 | 147 |
| 2022 July | 108 | 54 | 162 |
| 2022 June | 91 | 48 | 139 |
| 2022 May | 72 | 49 | 121 |
| 2022 April | 67 | 43 | 110 |
| 2022 March | 80 | 69 | 149 |
| 2022 February | 67 | 50 | 117 |
| 2022 January | 93 | 54 | 147 |
| 2021 December | 75 | 62 | 137 |
| 2021 November | 69 | 40 | 109 |
| 2021 October | 68 | 71 | 139 |
| 2021 September | 56 | 55 | 111 |
| 2021 August | 77 | 47 | 124 |
| 2021 July | 67 | 34 | 101 |
| 2021 June | 102 | 65 | 167 |
| 2021 May | 178 | 75 | 253 |
| 2021 April | 341 | 200 | 541 |
| 2021 March | 208 | 77 | 285 |
| 2021 February | 175 | 66 | 241 |
| 2021 January | 92 | 33 | 125 |
| 2020 December | 141 | 37 | 178 |
| 2020 November | 131 | 35 | 166 |
| 2020 October | 335 | 54 | 389 |
| 2020 September | 99 | 14 | 113 |
Show all
