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                        "fecha" => "1998"
                        "volumen" => "47"
                        "paginaInicial" => "673"
                        "paginaFinal" => "676"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Identifica&#231;&#227;o de Leptospirose em tecido pulmonar por broncoscopia e bi&#243;psia br&#244;nquica"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46;E&#46; Manh&#227;es de Carvalho"
                            1 => "J&#46;M&#46;C&#46; Oliveira"
                            2 => "A&#46;F&#46; Nicol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pulm&#227;o RJ"
                        "fecha" => "1999"
                        "volumen" => "8"
                        "numero" => "4"
                        "paginaInicial" => "337"
                        "paginaFinal" => "381"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Leptospirose pulmonar"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46;J&#46; Rios Gon&#231;alves"
                            1 => "J&#46;E&#46; Manh&#227;es de Carvalho"
                            2 => "J&#46;B&#46; Guedes e Silva"
                            3 => "R&#46; Rosenbaum"
                            4 => "A&#46;R&#46; Machado Vieira"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Rev Soc Bras Med Trop"
                        "fecha" => "1992"
                        "volumen" => "25"
                        "numero" => "4"
                        "paginaInicial" => "261"
                        "paginaFinal" => "270"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1340542"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Selected Reports- -Leptospiral Pneumonia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "O&#46;F&#46; Teglta"
                            1 => "C&#46; Battagliotti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1995"
                        "volumen" => "108"
                        "numero" => "3"
                        "paginaInicial" => "874"
                        "paginaFinal" => "879"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7656649"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Leptospirose"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E&#46;S&#46; Machado"
                            1 => "S&#46;A&#46; Nogueira"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:2 [
                        "titulo" => "Manual de Emerg&#234;ncias M&#233;dicas- -Diagn&#243;stico e Tratamento-Rotina do Servi&#231;o de Emerg&#234;ncia do Hospital Universit&#225;rio Clementino Fraga Filho-UFRJ&#44;Segunda Edi&#231;&#227;o&#46;"
                        "serieFecha" => "2003"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "transmiss&#227;o da leptospirose em &#225;reas A urbanas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;S&#46; Ripper-Vianna"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cadernos de Sa&#250;de P&#250;blica"
                        "fecha" => "2004"
                        "volumen" => "20"
                        "numero" => "6"
                        "paginaInicial" => "32"
                        "paginaFinal" => "35"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Osservazioni clinico-radiologiche sulle manifestazioni polmonari da leptospirosi durantte l&#8216;epidemia de Montefeltro"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46;G&#46; Ercolani"
                            1 => "M&#46; Papa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "La Radiologia Medica"
                        "fecha" => "1988"
                        "volumen" => "76"
                        "numero" => "1&#8211;2"
                        "paginaInicial" => "64"
                        "paginaFinal" => "67"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3399710"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outbreak of leptospirosis with pulmonary involviment in North Andaman"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "S&#46;C&#46; Sehgal"
                            1 => "M&#46;V&#46; Murhekar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Indian Journal of Medical Research"
                        "fecha" => "1995"
                        "volumen" => "102"
                        "paginaInicial" => "9"
                        "paginaFinal" => "12"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7558211"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemic leptospirosis associated with pulmonary hemorrhage-Nicaragua 1995"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "R&#46;T&#46; Trevejo"
                            1 => "J&#46;G&#46; Rigau-Perez"
                            2 => "D&#46;A&#46; Ashford"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Journal of Infectious Diseases"
                        "fecha" => "1998"
                        "volumen" => "178"
                        "numero" => "5"
                        "paginaInicial" => "1457"
                        "paginaFinal" => "1463"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9780268"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Les facteurs re risque de leptospirose em France&#58; une &#233;tude c&#227;s-t&#233;moins nationale&#40;1999&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "A&#46; Nardone"
                            1 => "C&#46; Campese"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "M&#233;d Mal Infect"
                        "fecha" => "2001"
                        "volumen" => "31"
                        "numero" => "Suppl 2"
                        "paginaInicial" => "285"
                        "paginaFinal" => "287"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hemorragies intra-alveolaires patentes et occultes au cours des leptospiroses"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "L&#46; Du Couedic"
                            1 => "J&#46;P&#46; Courtin"
                            2 => "P&#46; Poubeau"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Revue de Maladies Respiratoires"
                        "fecha" => "1998"
                        "volumen" => "15"
                        "numero" => "1"
                        "paginaInicial" => "61"
                        "paginaFinal" => "67"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hipotension&#44; renal failure and pulmonary complications in leptospirosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "K&#46; Niwattayakul"
                            1 => "J&#46; Howivijitkul"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Renal Failure"
                        "fecha" => "2002"
                        "volumen" => "24"
                        "numero" => "3"
                        "paginaInicial" => "297"
                        "paginaFinal" => "305"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12166696"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Estudo do lavado broncoalveolar em pacientes com comprometimento pulmonar na leptospirose"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "J&#46;E&#46; Manh&#227;es de Carvalho"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Bras Pneumol"
                        "fecha" => "2004"
                        "volumen" => "30"
                        "numero" => "2"
                        "paginaInicial" => "134"
                        "paginaFinal" => "139"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Leptospirosis presenting as Diffuse Alveolar Hemorrhage-Case Report and Literature Review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "M&#46;A&#46; Lucks"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2003"
                        "volumen" => "123"
                        "numero" => "2"
                        "paginaInicial" => "639"
                        "paginaFinal" => "643"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12576395"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Manifestations pulmonaires predominantes au cours de leptospiroses icteroh&#233;morragiques"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "P&#46;H&#46; Carr&#233;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Revue de Maladies Respiratoire"
                        "fecha" => "1985"
                        "volumen" => "2"
                        "numero" => "6"
                        "paginaInicial" => "343"
                        "paginaFinal" => "349"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Leptospirosis associated with severe pulmonary haemorrhage in Far North Queensland"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "F&#46;G&#46; Simpson"
                            1 => "K&#46;A&#46; Green"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Medical Journal of Australia"
                        "fecha" => "1998"
                        "volumen" => "169"
                        "numero" => "3"
                        "paginaInicial" => "151"
                        "paginaFinal" => "153"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9734512"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
              "etiqueta" => "27&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lung lesions in human leptospirosis&#58; microscopic&#44; immunohistochemical and ultrastructural features related to thrombocytopenia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "A&#46;C&#46; Nicodemo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "American Journal of Tropical Medicine and Hygiene"
                        "fecha" => "1997"
                        "volumen" => "56"
                        "numero" => "2"
                        "paginaInicial" => "181"
                        "paginaFinal" => "187"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9080878"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib28"
              "etiqueta" => "28&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary Capillaritis and Alveolar Hemorrhage&#8211;Update on Diagnosis and Management"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "R&#46;J&#46; Green"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1996"
                        "volumen" => "110"
                        "numero" => "5"
                        "paginaInicial" => "1305"
                        "paginaFinal" => "1316"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8915239"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib29"
              "etiqueta" => "29&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Manifestations Pulmonaires au cors de leptospiroses icteroh&#233;morragiques severes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "J&#46;M&#46; Ragnaud"
                            1 => "M&#46; Dupon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Annales de Medicine Interne"
                        "fecha" => "1987"
                        "volumen" => "138"
                        "numero" => "4"
                        "paginaInicial" => "282"
                        "paginaFinal" => "286"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib30"
              "etiqueta" => "30&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comprometimento pulmonar na leptospirose"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "J&#46;M&#46; Manh&#227;es de Carvalho"
                            1 => "E&#46; Marchiori"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Revista da Sociedade Brasileira de Medicina Tropical"
                        "fecha" => "1992"
                        "volumen" => "25"
                        "numero" => "1"
                        "paginaInicial" => "21"
                        "paginaFinal" => "30"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1308063"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib31"
              "etiqueta" => "31&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Leptospirosis as a cause of Acute Respiratory Failure&#58; Clinical Features and Outcome in 35 critical care patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46;R&#46;R&#46; Vieira"
                            1 => "J&#46;S&#46; Brauner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "The Brazilian Journal of Infectious Diseases"
                        "fecha" => "2002"
                        "volumen" => "6"
                        "numero" => "3"
                        "paginaInicial" => "135"
                        "paginaFinal" => "139"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12144750"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib32"
              "etiqueta" => "32&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#201;tats de Choc au cours de Leptospiroses ictero-h&#233;morragiques Quatre observations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "G&#46; Guivarch"
                            1 => "J&#46;R&#46; Le Gall"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "La Nouvelle Presse Medicale"
                        "fecha" => "1982"
                        "volumen" => "11"
                        "numero" => "11"
                        "paginaInicial" => "837"
                        "paginaFinal" => "839"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7070975"
                            "web" => "Medline"
                          ]
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                ]
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Massive pulmonary hemorrhage due to leptospirosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46; Allen"
                            1 => "S&#46; Raffery"
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                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Intensive Care Medicine"
                        "fecha" => "1989"
                        "volumen" => "15"
                        "numero" => "5"
                        "paginaInicial" => "322"
                        "paginaFinal" => "324"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2768647"
                            "web" => "Medline"
                          ]
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                ]
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            33 => array:3 [
              "identificador" => "bib34"
              "etiqueta" => "34&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary manifestations of leptospirosis"
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                          "etal" => true
                          "autores" => array:1 [
                            0 => "K&#46;M&#46; O&#8216;Neil"
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                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Review of Infectious Diseases"
                        "fecha" => "1991"
                        "volumen" => "13"
                        "numero" => "4"
                        "paginaInicial" => "705"
                        "paginaFinal" => "709"
                      ]
                    ]
                  ]
                ]
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            34 => array:3 [
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Leptospirosis of the lung&#58; radiographic findings in 58 patients"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46;G&#46; Im"
                            1 => "K&#46;M&#46; Yeon"
                            2 => "M&#46;C&#46; Han"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2214/ajr.152.5.955"
                      "Revista" => array:7 [
                        "tituloSerie" => "AJR"
                        "fecha" => "1989"
                        "volumen" => "152"
                        "numero" => "5"
                        "paginaInicial" => "955"
                        "paginaFinal" => "959"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2705352"
                            "web" => "Medline"
                          ]
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                ]
              ]
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            35 => array:3 [
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Leptospirose icteroh&#233;morragique avec syndrome de detresse respiratoire aigu&#234; et hemorragie pulmonaire"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "T&#46;K&#46; Vuong"
                            1 => "J&#46;P&#46; Laaban"
                            2 => "A&#46; Rabbat"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Revue de Maladies Respiratoires"
                        "fecha" => "1991"
                        "volumen" => "8"
                        "numero" => "2"
                        "paginaInicial" => "256"
                        "paginaFinal" => "257"
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                    ]
                  ]
                ]
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            36 => array:3 [
              "identificador" => "bib37"
              "etiqueta" => "37&#46;"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hemorragie intra-alveolaire f&#233;brile isole&#233; r&#233;velant une leptospirose"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:4 [
                            0 => "M&#46;J&#46; Labalme"
                            1 => "S&#46; Chaabane-Masmoudi"
                            2 => "L&#46; Mathieu"
                            3 => "M&#46; Perol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "R&#233;vue de Maladies Respiratoire"
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                        "volumen" => "13"
                        "numero" => "3"
                        "paginaInicial" => "310"
                        "paginaFinal" => "312"
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                ]
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            37 => array:3 [
              "identificador" => "bib38"
              "etiqueta" => "38&#46;"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hemoptysis and the Adult Respiratory Distress Syndrome as the cause of death in leptospirosis&#58; changes in the clinical and anatomicopathological patterns"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "A&#46;J&#46;R&#46; Gon&#231;alves"
                            1 => "J&#46;E&#46;M&#46; Carvalho"
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                    ]
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Revista Sociedade Brasileira de Medicina Tropical"
                        "fecha" => "1992"
                        "volumen" => "54"
                        "paginaInicial" => "382"
                        "paginaFinal" => "392"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            38 => array:3 [
              "identificador" => "bib39"
              "etiqueta" => "39&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchoalveolar lavage in rapid diagnosis of leptospirosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "Paganin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1996"
                        "volumen" => "347"
                        "paginaInicial" => "1483"
                        "paginaFinal" => "1484"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8676650"
                            "web" => "Medline"
                          ]
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                    ]
                  ]
                ]
              ]
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            39 => array:3 [
              "identificador" => "bib40"
              "etiqueta" => "40&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chest Radiograph abnormalities in patients hospitalized with leptospirosis in the City of Salvador&#44; Bahia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E&#46;D&#46; Matos"
                            1 => "E&#46; Costa"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Brazil&#46; The Brazilian Journal of Infectious Diseases"
                        "fecha" => "2001"
                        "volumen" => "5"
                        "numero" => "2"
                        "paginaInicial" => "73"
                        "paginaFinal" => "77"
                      ]
                    ]
                  ]
                ]
              ]
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            40 => array:3 [
              "identificador" => "bib41"
              "etiqueta" => "41&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The chest radiograph in leptospirosis in Jamaica"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "R&#46;E&#46; Lee"
                            1 => "S&#46;I&#46; Terry"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1259/0007-1285-54-647-939"
                      "Revista" => array:7 [
                        "tituloSerie" => "British Journal of Radiology"
                        "fecha" => "1981"
                        "volumen" => "54"
                        "numero" => "647"
                        "paginaInicial" => "939"
                        "paginaFinal" => "943"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7306765"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            41 => array:3 [
              "identificador" => "bib42"
              "etiqueta" => "42&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary involvement in leptospirosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "M&#46;A&#46; Martinez Garcia"
                            1 => "A&#46;D&#46; de Diego"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "European Journal of Clinical Microbiology and Infectious Diseases"
                        "fecha" => "2000"
                        "volumen" => "19"
                        "numero" => "6"
                        "paginaInicial" => "471"
                        "paginaFinal" => "474"
                      ]
                    ]
                  ]
                ]
              ]
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            42 => array:3 [
              "identificador" => "bib43"
              "etiqueta" => "43&#46;"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary haemorrhage as a predominant cause of death in leptospirosis in Seychelles"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:4 [
                            0 => "C&#46; Yersin"
                            1 => "P&#46; Bovet"
                            2 => "F&#46; Merien"
                            3 => "J&#46; Clement"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Transactions of the Royal Society of Tropical Medicine and Hygiene"
                        "fecha" => "2000"
                        "volumen" => "94"
                        "numero" => "1"
                        "paginaInicial" => "71"
                        "paginaFinal" => "76"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10748905"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
            ]
            43 => array:3 [
              "identificador" => "bib44"
              "etiqueta" => "44&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The Clinicopathological and Immunohistochemical features of the severe pulmonary form of leptospirosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:4 [
                            0 => "J&#46;S&#46;P&#46; Silva"
                            1 => "M&#46;O&#46; Dalston"
                            2 => "J&#46;E&#46; Manh&#227;es de Carvalho"
                            3 => "S&#46; Set&#250;bal"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Revista da Sociedade Brasileira de Medicina Tropical"
                        "fecha" => "2002"
                        "volumen" => "35"
                        "numero" => "4"
                        "paginaInicial" => "395"
                        "paginaFinal" => "399"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12170336"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
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            44 => array:3 [
              "identificador" => "bib45"
              "etiqueta" => "45&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Leptospirosis of the lung&#58; high resolution computed tomography findings in five patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E&#46; Marchiori"
                            1 => "N&#46;L&#46; Muller"
                          ]
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Journal of Thoracic Imaging"
                        "fecha" => "2002"
                        "volumen" => "17"
                        "numero" => "2"
                        "paginaInicial" => "151"
                        "paginaFinal" => "153"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11956365"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
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                ]
              ]
            ]
            45 => array:3 [
              "identificador" => "bib46"
              "etiqueta" => "46&#46;"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sinais Radiol&#243;gicos da Doen&#231;a Tor&#225;cica"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#252;ller"
                            1 => "Fraser"
                            2 => "Par&#233;&#46; Colman"
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                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "In Diagn&#243;stico Radiol&#243;gico das Doen&#231;as do T&#243;rax&#46; Primeira Edi&#231;&#227;o"
                        "fecha" => "2003"
                        "editorial" => "Guanabara Koogan"
                        "editorialLocalizacion" => "Rio de Janeiro"
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                    ]
                  ]
                ]
              ]
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            46 => array:3 [
              "identificador" => "bib47"
              "etiqueta" => "47&#46;"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Doen&#231;as Pulmonares Difusas"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "Naidich"
                            1 => "Webb"
                            2 => "Muller"
                            3 => "Krinsky"
                            4 => "Zerhouni"
                            5 => "Siegelman"
                          ]
                        ]
                      ]
                    ]
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                  "host" => array:1 [
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                      "Libro" => array:4 [
                        "titulo" => "In Tomografia Computadorizada e Resson&#226;ncia Magn&#233;tica do T&#243;rax&#46; Terceira Edi&#231;&#227;o"
                        "fecha" => "2001"
                        "editorial" => "Guanabara Koogan"
                        "editorialLocalizacion" => "Rio de Janeiro"
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                  ]
                ]
              ]
            ]
            47 => array:3 [
              "identificador" => "bib48"
              "etiqueta" => "48&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acute lung injury in leptospirosis&#58; clinical and laboratory features outcome and factors associated with mortality"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "P&#46;C&#46; Marotto"
                            1 => "C&#46;M&#46; Nascimento"
                            2 => "J&#46; Eluf Neto"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/313501"
                      "Revista" => array:7 [
                        "tituloSerie" => "Clinical Infectious Diseases"
                        "fecha" => "1999"
                        "volumen" => "29"
                        "numero" => "6"
                        "paginaInicial" => "1561"
                        "paginaFinal" => "1563"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10585813"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
            ]
            48 => array:3 [
              "identificador" => "bib49"
              "etiqueta" => "49&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Massive pulmonary haemorrhage caused by leptospirosis successfully treated with nitric oxide inhalation and haemofiltration"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Borer"
                            1 => "I&#46; Metz"
                            2 => "J&#46; Gilad"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Journal of Infection"
                        "fecha" => "1999"
                        "volumen" => "38"
                        "numero" => "1"
                        "paginaInicial" => "42"
                        "paginaFinal" => "45"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10090507"
                            "web" => "Medline"
                          ]
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                ]
              ]
            ]
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              "identificador" => "bib50"
              "etiqueta" => "50&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hemorragie alveolaire diffuse et myosite au cours d&#8216;une leptospirose ictero-hemorragique Contr&#244;le rapide par un seul bolus du corticoids"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46;P&#46; Courtin"
                            1 => "P&#46; Carre"
                            2 => "P&#46; Poubeau"
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                      ]
                    ]
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Revue de Maladies Respiratoires"
                        "fecha" => "1994"
                        "volumen" => "11"
                        "paginaInicial" => "601"
                        "paginaFinal" => "603"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            50 => array:3 [
              "identificador" => "bib51"
              "etiqueta" => "51&#46;"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A case of Weil&#39;s Disease requiering steroid therapy for thrombocytopenia and bleeding"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46;B&#46; Kahn"
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                    ]
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Trop Med Hyg"
                        "fecha" => "1982"
                        "volumen" => "31"
                        "paginaInicial" => "1213"
                        "paginaFinal" => "1216"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7149105"
                            "web" => "Medline"
                          ]
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                    ]
                  ]
                ]
              ]
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              "identificador" => "bib52"
              "etiqueta" => "52&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The role of glucocorticoid pulse therapy in pulmonary involvement in leptospirosis"
                      "autores" => array:1 [
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                          "etal" => true
                          "autores" => array:4 [
                            0 => "S&#46;V&#46; Trivedi"
                            1 => "R&#46;K&#46; Chavda"
                            2 => "P&#46;Z&#46; Wadia"
                            3 => "V&#46; Sheth"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Am Physicians India"
                        "fecha" => "2001"
                        "volumen" => "49"
                        "paginaInicial" => "901"
                        "paginaFinal" => "903"
                      ]
                    ]
                  ]
                ]
              ]
            ]
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Vol. 13. Issue 6.
Pages 827-839 (November - December 2007)
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Vol. 13. Issue 6.
Pages 827-839 (November - December 2007)
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Leptospirose pulmonar
Pulmonary leptospirosis
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João Cláudio Barroso Pereira1, Amorita Grijó2, Maria Cristina B Mackay3, Beatriz Guerra Vitral4, Sra Althair de Araújo Silva5, Cláudio de Castro Lázaro6
1 Médico da Emergência do Hospital Municipal Nelson de Sá Earp – Município de Petrópolis, Rio de Janeiro – Brasil, e médico tisiologista do Serviço da Assistência Especializada-SAE da prefeitura Municipal de Belford Roxo – Rio de Janeiro-Brasil
2 Médica infectologista da prefeitura de Petrópolis e Professora da Faculdade de Medicina de Petrópolis
3 Médica infectologista da prefeitura de Petrópolis e Professora da Faculdade de Medicina de Petrópolis
4 Médica infectologista da prefeitura de Petrópolis e Professora da Faculdade de Medicina de Petrópolis
5 Administradora do Serviço de Atendimento Especializado, Belford Roxo – Rio de Janeiro
6 Director Geral do Hospital Municipal Nelson de Sá Earp, Petrópolis – Rio de Janeiro
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Resumo

No presente artigo, os autores discutem brevemente sobre a leptospirose, realçando a forma pulmonar da doença. Revê-se a patologia, achados clínicos, diagnóstico por métodos de imagem e broncoscopia e tratamento da leptospirose pulmonar. É também lembrado o diagnóstico clínico e radiológico precoces, para que se possa iniciar terapêutica adequada. Os autores concluem que a forma pulmonar da leptospirose deve ser sempre considerada como causa e diagnóstico diferencial da hemorragia alveolar difusa e síndroma de dificuldade respiratória do adulto.

Palavras-chave:
Leptospirose
manifestações respiratórias
hemorragia alveolar difusa e síndroma da dificuldade respiratória do adulto
Abstract

In this article, the authors discuss briefly the leptospirosis, emphasizing mainly the pulmonary form of disease. The authors review pathology, clinical findings, imaging and broncoscopy diagnosis, treatment of pulmonary leptospirosis. It is also remembered about early clinics and radiology diagnosis to start therapeutics. The authors conclude that pulmonary form of disease must always be remembered and considered as cause and differential diagnosis of Diffuse Alveolar Hemorrhage and Adult Respiratory Distress Syndrome.

Key-words:
Leptospirosis
respiratory manifestations
diffuse alveolar hemorrhage and adult respiratory distress syndrome
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Bibliografia
[1.]
F.S.V. Martins, T.M.P.P. Castiñeras.
Leptospirose.
Doenças Infecciosas-Conduta Diagnóstica e, Terapêutica, Primeira, Edição, pp. 145-152
[2.]
C.D. Huston, J.W.A. Petri.
Leptospirosis In Cecil Textbook of Medicine.
22nd Edition, Pennsylvania:, (2004),
[3.]
R.R. Sambasiva, R.R.S. Gupta Naveen, P. Bhalla, S.K. Agarwal.
Leptospirosis in India and the Rest of the World. The Brazilian Journal of Infectious Diseases, 7 (2003), pp. 178-193
[4.]
M.D. Hüttner, et al.
Pneumonia por leptospirose.
J Pneumol, 28 (2002), pp. 229-232
[5.]
M.Z. Gomes Ribeiro, M.C. Carvalho Pereira, E. Condé.
Rotina de Leptospirose do Instituto Estadual de Infectologia São Sebastião. Reproduzida pela Secretaria Estadual de Saúde.
Serviço Único de Saúde-Coordenação de Epidemiologia, Dezembro de, (1995),
[6.]
A.V. Lomar, R. Veronesi, T. Brito, D. Diament.
Leptospiroses.
Tratado de Infectologia., pp. 987-1003
[7.]
Ministério da Saúde/FUNASA/CENEPI. Manual de Leptospirose. Segunda Ed revista. Brasília: Fundação Nacional de Saúde, 1995. 98 pp.
[8.]
L.F. Mascarenhas, A.J. Rios Gonçalves, R. Da Cunha, J.A. Menezes, et al.
Manifestações Respiratórias na Leptospirose.
Arq Bras Med, 65 (1991), pp. 49-51
[9.]
E.P. Bethlem.
Leptospirose Manifestações Pulmonares. Aula realizada durante V Curso Nacional de Atualização em Pneumologia.
Rio de Janeiro, (2004), pp. 125-131
[10.]
Centers for Disease Control and Prevention.
Outbreak of acute febrile illness among participants in Ecochallenge Sabah 2000-Malaysia, 2000.
Morb Mortal WKly Rep, 49 (2000), pp. 816-817
[11.]
Centers for Disease Control and Prevention.
Leptospirosis and unexplained acute febrile illness among athletes participating in Triathlons-Illinois and Wiscousin, 1998.
Morb Mortal WKly Rep, 47 (1998), pp. 673-676
[12.]
J.E. Manhães de Carvalho, J.M.C. Oliveira, A.F. Nicol, et al.
Identificação de Leptospirose em tecido pulmonar por broncoscopia e biópsia brônquica.
Pulmão RJ, 8 (1999), pp. 337-381
[13.]
A.J. Rios Gonçalves, J.E. Manhães de Carvalho, J.B. Guedes e Silva, R. Rosenbaum, A.R. Machado Vieira.
Leptospirose pulmonar.
Rev Soc Bras Med Trop, 25 (1992), pp. 261-270
[14.]
O.F. Teglta, C. Battagliotti, et al.
Selected Reports- -Leptospiral Pneumonia.
Chest, 108 (1995), pp. 874-879
[15.]
E.S. Machado, S.A. Nogueira.
Leptospirose.
Manual de Emergências Médicas- -Diagnóstico e Tratamento-Rotina do Serviço de Emergência do Hospital Universitário Clementino Fraga Filho-UFRJ,Segunda Edição.,
[16.]
M.S. Ripper-Vianna.
transmissão da leptospirose em áreas A urbanas.
Cadernos de Saúde Pública, 20 (2004), pp. 32-35
[17.]
M.G. Ercolani, M. Papa.
Osservazioni clinico-radiologiche sulle manifestazioni polmonari da leptospirosi durantte l‘epidemia de Montefeltro.
La Radiologia Medica, 76 (1988), pp. 64-67
[18.]
S.C. Sehgal, M.V. Murhekar, et al.
Outbreak of leptospirosis with pulmonary involviment in North Andaman.
Indian Journal of Medical Research, 102 (1995), pp. 9-12
[19.]
R.T. Trevejo, J.G. Rigau-Perez, D.A. Ashford, et al.
Epidemic leptospirosis associated with pulmonary hemorrhage-Nicaragua 1995.
Journal of Infectious Diseases, 178 (1998), pp. 1457-1463
[20.]
A. Nardone, C. Campese, et al.
Les facteurs re risque de leptospirose em France: une étude cãs-témoins nationale(1999).
Méd Mal Infect, 31 (2001), pp. 285-287
[21.]
L. Du Couedic, J.P. Courtin, P. Poubeau, et al.
Hemorragies intra-alveolaires patentes et occultes au cours des leptospiroses.
Revue de Maladies Respiratoires, 15 (1998), pp. 61-67
[22.]
K. Niwattayakul, J. Howivijitkul, et al.
Hipotension, renal failure and pulmonary complications in leptospirosis.
Renal Failure, 24 (2002), pp. 297-305
[23.]
J.E. Manhães de Carvalho, et al.
Estudo do lavado broncoalveolar em pacientes com comprometimento pulmonar na leptospirose.
J Bras Pneumol, 30 (2004), pp. 134-139
[24.]
M.A. Lucks, et al.
Leptospirosis presenting as Diffuse Alveolar Hemorrhage-Case Report and Literature Review.
Chest, 123 (2003), pp. 639-643
[25.]
P.H. Carré, et al.
Manifestations pulmonaires predominantes au cours de leptospiroses icterohémorragiques.
Revue de Maladies Respiratoire, 2 (1985), pp. 343-349
[26.]
F.G. Simpson, K.A. Green, et al.
Leptospirosis associated with severe pulmonary haemorrhage in Far North Queensland.
Medical Journal of Australia, 169 (1998), pp. 151-153
[27.]
A.C. Nicodemo, et al.
Lung lesions in human leptospirosis: microscopic, immunohistochemical and ultrastructural features related to thrombocytopenia.
American Journal of Tropical Medicine and Hygiene, 56 (1997), pp. 181-187
[28.]
R.J. Green, et al.
Pulmonary Capillaritis and Alveolar Hemorrhage–Update on Diagnosis and Management.
Chest, 110 (1996), pp. 1305-1316
[29.]
J.M. Ragnaud, M. Dupon, et al.
Manifestations Pulmonaires au cors de leptospiroses icterohémorragiques severes.
Annales de Medicine Interne, 138 (1987), pp. 282-286
[30.]
J.M. Manhães de Carvalho, E. Marchiori, et al.
Comprometimento pulmonar na leptospirose.
Revista da Sociedade Brasileira de Medicina Tropical, 25 (1992), pp. 21-30
[31.]
S.R.R. Vieira, J.S. Brauner.
Leptospirosis as a cause of Acute Respiratory Failure: Clinical Features and Outcome in 35 critical care patients.
The Brazilian Journal of Infectious Diseases, 6 (2002), pp. 135-139
[32.]
G. Guivarch, J.R. Le Gall, et al.
États de Choc au cours de Leptospiroses ictero-hémorragiques Quatre observations.
La Nouvelle Presse Medicale, 11 (1982), pp. 837-839
[33.]
P. Allen, S. Raffery.
Massive pulmonary hemorrhage due to leptospirosis.
Intensive Care Medicine, 15 (1989), pp. 322-324
[34.]
K.M. O‘Neil, et al.
Pulmonary manifestations of leptospirosis.
Review of Infectious Diseases, 13 (1991), pp. 705-709
[35.]
J.G. Im, K.M. Yeon, M.C. Han, et al.
Leptospirosis of the lung: radiographic findings in 58 patients.
AJR, 152 (1989), pp. 955-959
[36.]
T.K. Vuong, J.P. Laaban, A. Rabbat, et al.
Leptospirose icterohémorragique avec syndrome de detresse respiratoire aiguê et hemorragie pulmonaire.
Revue de Maladies Respiratoires, 8 (1991), pp. 256-257
[37.]
M.J. Labalme, S. Chaabane-Masmoudi, L. Mathieu, M. Perol, et al.
Hemorragie intra-alveolaire fébrile isoleé révelant une leptospirose.
Révue de Maladies Respiratoire, 13 (1996), pp. 310-312
[38.]
A.J.R. Gonçalves, J.E.M. Carvalho, et al.
Hemoptysis and the Adult Respiratory Distress Syndrome as the cause of death in leptospirosis: changes in the clinical and anatomicopathological patterns.
Revista Sociedade Brasileira de Medicina Tropical, 54 (1992), pp. 382-392
[39.]
Paganin, et al.
Bronchoalveolar lavage in rapid diagnosis of leptospirosis.
Lancet, 347 (1996), pp. 1483-1484
[40.]
E.D. Matos, E. Costa.
Chest Radiograph abnormalities in patients hospitalized with leptospirosis in the City of Salvador, Bahia.
Brazil. The Brazilian Journal of Infectious Diseases, 5 (2001), pp. 73-77
[41.]
R.E. Lee, S.I. Terry, et al.
The chest radiograph in leptospirosis in Jamaica.
British Journal of Radiology, 54 (1981), pp. 939-943
[42.]
M.A. Martinez Garcia, A.D. de Diego, et al.
Pulmonary involvement in leptospirosis.
European Journal of Clinical Microbiology and Infectious Diseases, 19 (2000), pp. 471-474
[43.]
C. Yersin, P. Bovet, F. Merien, J. Clement, et al.
Pulmonary haemorrhage as a predominant cause of death in leptospirosis in Seychelles.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 94 (2000), pp. 71-76
[44.]
J.S.P. Silva, M.O. Dalston, J.E. Manhães de Carvalho, S. Setúbal, et al.
The Clinicopathological and Immunohistochemical features of the severe pulmonary form of leptospirosis.
Revista da Sociedade Brasileira de Medicina Tropical, 35 (2002), pp. 395-399
[45.]
E. Marchiori, N.L. Muller.
Leptospirosis of the lung: high resolution computed tomography findings in five patients.
Journal of Thoracic Imaging, 17 (2002), pp. 151-153
[46.]
Müller, Fraser, Paré. Colman.
Sinais Radiológicos da Doença Torácica.
In Diagnóstico Radiológico das Doenças do Tórax. Primeira Edição, Guanabara Koogan, (2003),
[47.]
Naidich, Webb, Muller, Krinsky, Zerhouni, Siegelman.
Doenças Pulmonares Difusas.
In Tomografia Computadorizada e Ressonância Magnética do Tórax. Terceira Edição, Guanabara Koogan, (2001),
[48.]
P.C. Marotto, C.M. Nascimento, J. Eluf Neto, et al.
Acute lung injury in leptospirosis: clinical and laboratory features outcome and factors associated with mortality.
Clinical Infectious Diseases, 29 (1999), pp. 1561-1563
[49.]
A. Borer, I. Metz, J. Gilad, et al.
Massive pulmonary haemorrhage caused by leptospirosis successfully treated with nitric oxide inhalation and haemofiltration.
Journal of Infection, 38 (1999), pp. 42-45
[50.]
J.P. Courtin, P. Carre, P. Poubeau, et al.
Hemorragie alveolaire diffuse et myosite au cours d‘une leptospirose ictero-hemorragique Contrôle rapide par un seul bolus du corticoids.
Revue de Maladies Respiratoires, 11 (1994), pp. 601-603
[51.]
J.B. Kahn.
A case of Weil's Disease requiering steroid therapy for thrombocytopenia and bleeding.
Am J Trop Med Hyg, 31 (1982), pp. 1213-1216
[52.]
S.V. Trivedi, R.K. Chavda, P.Z. Wadia, V. Sheth, et al.
The role of glucocorticoid pulse therapy in pulmonary involvement in leptospirosis.
J Am Physicians India, 49 (2001), pp. 901-903
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