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Journal Information
Vol. 13. Issue 1.
Pages 137-142 (January - February 2007)
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Vol. 13. Issue 1.
Pages 137-142 (January - February 2007)
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Linfoma MALT do pulmão – Uma forma rara de linfoma
Pulmonary MALT lymphoma – A rare form of lymphoma
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João Meneses Santos, Raed Zakout, Carlos Ferreira, Maria João Palhano, Rui MM Victorino
1 Assistente Hospitalar Graduado de Medicina Interna – Serviço de Medicina 2 do HSM
2 Interno do Internato Complementar de Medicina Interna – Serviço de Medicina 2 do HSM
3 Chefe de Serviço de Medicina Interna – Serviço de Medicina 2 do HSM / Professor Auxiliar da Faculdade de Medicina de Lisboa
4 Assistente Hospitalar Graduada de Anatomia Patológica – Serviço de Anatomia Patológica do HSM
5 Director do Serviço de Medicina 2 do Hospital de Santa Maria / Professor Catedrático da Faculdade de Medicina de Lisboa
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Resumo

Os autores apresentam um caso de linfoma MALT do pulmão numa doente assintomática mas com imagens radiológicas exuberantes, cujo diagnóstico só foi possível por biópsia pulmonar cirúrgica obtida por toracoscopia assistida por vídeo, após a ineficácia da biópsia pulmonar transbrônquica e da punção aspirativa transtorácica. Descrevem os aspectos clínicos e radiológicos daquela forma de linfoma, salientando a possibilidade de expressão assintomática prolongada e discutem problemas de diagnóstico, prognóstico e terapêutica.

Palavras-chave:
Linfoma MALT
Linfoma MALT do pulmão
Biópsia pulmonar cirúrgica
Abstract

The authors report a case of pulmonary MALT lymphoma in an asymptomatic patient with a chest radiograph showing bilateral infiltrates. The diagnosis was made by surgical lung biopsy performed by videoassisted thoracoscopy. The transbronchial lung and the transthoracic core-needle biopsies were non- -diagnostic. The clinical and radiological features of the pulmonary MALT lymphoma are described and relevant diagnostic, prognostic and treatment factors are discussed.

Key-words:
MALT lymphoma
Pulmonary MALT lymphoma
Surgical lung biopsy
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Bibliografia
[1.]
P. Isaacson, D.H. Wright.
Malignant lymphoma of mucosa- associated lymphoid tissue. A distinctive type of B-cell lymphoma.
Cancer, 52 (1983), pp. 1410-1416
[2.]
E. Zucca, A. Conconi, E. Pedrinis, et al.
Nongastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue.
Blood, 101 (2003), pp. 2489-2495
[3.]
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Primary Pulmonary Lymphoma.
Eur Respir J, 20 (2002), pp. 750-762
[4.]
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Boudreaux. Pulmonary lymphoma of the mucosa-associated lymphoid tissue type: report of a case with cytological, histological, immunophenotypical correlation, and review of the literature.
Annals of Diagnostic Pathology, 9 (2005), pp. 148-152
[5.]
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[6.]
B. Streubel, A. Lamprecht, J. Dierlamm, et al.
T(14;18)(q32;q21) involving IGH and MALT1 is a frequent chromosomal aberration in MALT lymphoma.
Blood, (2003), pp. 2335-2339
[7.]
P.G. Isaacson.
Update on MALT lymphomas.
Bes Pract R Clin Haematol, 18 (2005), pp. 57-68
[8.]
Jung Han Kim, Se-Hoon Lee, Jinny Park, et al.
Primary Pulmonary Non-Hodgkin‘s Lymphoma.
Jpn J Clin Oncol, 34 (2004), pp. 510-514
Copyright © 2007. Sociedade Portuguesa de Pneumologia
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