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Letter to the Editor
DOI: 10.1016/j.pulmoe.2019.10.005
Open Access
Available online 18 November 2019
Pneumocystosis pneumonia in immunocompromised patients
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Beuy Jooba,
Corresponding author
beuyjoob@hotmail.com

Corresponding author.
a Sanitation 1 Medical Academic Center, Bangkok, Thailand
Viroj Wiwanitkitb
b Honorary professor, dr DY Patil University, Pune, India
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Received 21 October 2019
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Dear Editor,

We read the publication on “Pneumocystosis pneumonia: A comparison study between HIV and non-HIV immunocompromised patients” with a great interest.1 Rego de Figueiredo et al. reported that “non-HIV patients had worse outcomes with higher incidence of invasive mechanical ventilation.”1 Pneumocystosis pneumonia is an important infection that can be seen in an immunocompromised host, regardless of HIV serological status. General practitioners usually recognize pneumocystosis pneumonia as an important complication in HIV - infected patients. The worse clinical outcome in non-HIV patientsmight be due to delayed or under diagnosis. According to a recent report by Li et al.,2 a delay between admission and starting antimicrobial therapy was common and a longer delay time period was observed in non-HIV infected cases.3 In addition, specific guidelines for management and prophylaxis of pneumocystosis pneumonia in non-HIV immunocompromised patient are seldom mentioned.3,4 Practitioners should recognize and include of pneumocystosis pneumonia in the differential diagnosis of pneumonia in any immunocompromised host regardless of HIV serostatus.

Ethical disclosure

No conflict of interest.

No funding.

The work is a letter to editor and requires no ethical committee approval or written informed consent.

Both authors equally contribute and approve for the final manuscript.

Conflict of interest

The authors have no conflicts of interest to declare.

References
[1]
I. Rego de Figueiredo, R. Vieira Alves, D. Drummond Borges, M. Torres, F. Lourenço, A.M. Antunes, et al.
Pneumocystosis pneumonia: a comparison study between HIV and non-HIV immunocompromised patients.
Pulmonology, 25 (2019), pp. 271-274
[2]
M.C. Li, N.Y. Lee, C.C. Lee, H.C. Lee, C.M. Chang, W.C. Ko.
Pneumocystis jiroveci pneumonia in immunocompromised patients: delayed diagnosis and poor outcomes in non-HIV-infected individuals.
J Microbiol Immunol Infect, 47 (2014), pp. 42-47
[3]
H.J.F. Salzer, G. Schäfer, M. Hoenigl, G. Günther, C. Hoffmann, B. Kalsdorf, et al.
Clinical, diagnostic, and treatment disparities between HIV-infected and non-HIV-infected immunocompromised patients with pneumocystis jirovecii pneumonia.
Respiration, 96 (2018), pp. 52-65
[4]
L.J. Avino, S.M. Naylor, A.M. Roecker.
Pneumocystis jirovecii Pneumonia in the Non-HIV-Infected Population.
Ann Pharmacother, 50 (2016), pp. 673-679
Copyright © 2019. Sociedade Portuguesa de Pneumologia
Pulmonology

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