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        "resumen" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">In this paper we present a study whose main aim is the measurement of the Health Related Quality of Life &#40;HRQoL&#41; of patients with asthma and the presentation of a first draft of normative values as measured by the SF-6D for asthma patients&#46; In addition&#44; we investigate how far non-disease-specific HRQoL measures can distinguish groups in terms of sociodemographic characteristics&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The Portuguese versions of the EQ-5D&#44; SF-6D&#44; AQLQ&#40;S&#41; and ACQ were administered using personal interviews to a representative sample of the Portuguese population with asthma&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Most of the individuals did not report significant problems in the dimensions used&#44; with the exception of the physical functioning&#44; where individuals reported moderate limitations&#46; The mean utility value was 0&#46;86&#46; Male gender&#44; young&#44; single&#44; individuals with high educational attainment level&#44; employed&#44; individuals with high income and those residing in urban areas reported higher utility levels&#46; As expected&#44; those who were in a severe stadium of the disease reported lower mean utility levels than those who were in a less severe stadium of the disease&#46; Normative values for the SF-6D were computed for patients with asthma by gender&#44; age&#44; marital status&#44; educational attainment level&#44; employment status&#44; area of residence and average monthly net income&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The preference-based measures used in this study distinguish patient groups with asthma in terms of socio-demographic groups&#46; The normative values can be used in economic evaluation and clinical studies as they incorporate patients&#8217; preferences and translate the value attributed to patients&#8217; health state&#46;</p>"
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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Neste artigo &#233; descrito um estudo&#44; cujo objectivo &#233; a medi&#231;&#227;o da qualidade de vida relacionada com a sa&#250;de &#40;QdVRS&#41; de doentes com asma e a apresenta&#231;&#227;o de uma primeira aproxima&#231;&#227;o aos valores normativos&#44; com base no SF-6D&#44; para aquele tipo de doentes&#46; Pretende-se ainda averiguar a capacidade de medidas gen&#233;ricas de medi&#231;&#227;o da QdVRS distinguirem grupos em termos de caracter&#237;sticas sociodemogr&#225;ficas&#46; Aplicaram-se&#44; por entrevista pessoal&#44; as vers&#245;es portuguesas do EQ-5D&#44; do SF-6D&#44; do AQLQ&#40;S&#41; e do ACQ a uma amostra representativa da popula&#231;&#227;o portuguesa com asma&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A maioria dos indiv&#237;duos n&#227;o apresentou problemas significativos nas dimens&#245;es medidas&#44; excepto na fun&#231;&#227;o f&#237;sica&#44; onde os indiv&#237;duos reportaram limita&#231;&#245;es moderadas&#46; Em m&#233;dia&#44; os inquiridos apresentam valores de utilidade de 0&#44;86&#46; Os homens&#44; os mais jovens&#44; os solteiros&#44; os indiv&#237;duos com habilita&#231;&#245;es liter&#225;rias mais elevadas&#44; os empregados&#44; os indiv&#237;duos com rendimentos mais elevados e aqueles que residiam em zonas urbanas foram os que reportaram n&#237;veis de utilidade mais elevados&#46; Por outro lado&#44; os indiv&#237;duos que se encontravam num est&#225;dio mais avan&#231;ado da doen&#231;a reportaram&#44; como era de esperar&#44; n&#237;veis m&#233;dios de utilidade inferiores aos dos que se encontravam num est&#225;dio menos grave da doen&#231;a&#46; Foram obtidos valores normativos para o SF-6D para doentes com asma por g&#233;nero&#44; grupo et&#225;rio&#44; estado civil&#44; habilita&#231;&#245;es liter&#225;rias&#44; situa&#231;&#227;o profissional&#44; local de resid&#234;ncia e rendimento m&#233;dio mensal l&#237;quido&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">As medidas de utilidade baseadas em prefer&#234;ncias utilizadas neste estudo discriminam adequadamente grupos de doentes com asma&#44; de acordo com grupos sociodemogr&#225;ficos&#46; Os valores normativos obtidos podem ser usados em estudos de avalia&#231;&#227;o econ&#243;mica e estudos cl&#237;nicos&#44; uma vez que incorporam as prefer&#234;ncias dos doentes e traduzem a utilidade atribu&#237;da ao seu estado de sa&#250;de&#46;</p>"
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                          "autores" => array:6 [
                            0 => "M&#46; Rutten-van M&#246;lken"
                            1 => "F&#46; Custers"
                            2 => "E&#46; Van Doorslaer"
                            3 => "C&#46; Jansen"
                            4 => "L&#46; Heurman"
                            5 => "F&#46; Maesen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "1995"
                        "volumen" => "8"
                        "paginaInicial" => "888"
                        "paginaFinal" => "898"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7589374"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Association of asthma control with health care utilization and quality of life"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "W&#46; Vollmer"
                            1 => "L&#46; Markson"
                            2 => "E&#46; O&#8217;Connor"
                            3 => "L&#46; Sanocki"
                            4 => "L&#46; Fitterman"
                            5 => "M&#46; Berger"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.160.5.9902098"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "1999"
                        "volumen" => "160"
                        "paginaInicial" => "1647"
                        "paginaFinal" => "1652"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10556135"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A medi&#231;&#227;o de prefer&#234;ncias em sa&#250;de na popula&#231;&#227;o portuguesa"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46; Ferreira"
                            1 => "L&#46; Ferreira"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Port Sa&#250;de P&#250;blica"
                        "fecha" => "2006"
                        "volumen" => "24"
                        "paginaInicial" => "5"
                        "paginaFinal" => "14"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A single European currency for EQ-5D health states&#58; Results from a six-country study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "W&#46; Greiner"
                            1 => "T&#46; Weijnen"
                            2 => "M&#46; Nieuwenhuizen"
                            3 => "S&#46; Oppe"
                            4 => "X&#46; Badia"
                            5 => "J&#46; Busschbach"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s10198-003-0182-5"
                      "Revista" => array:6 [
                        "tituloSerie" => "European Journal of Health Economics"
                        "fecha" => "2003"
                        "volumen" => "4"
                        "paginaInicial" => "222"
                        "paginaFinal" => "231"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15609189"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "EuroQol&#58; the current state of play"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46; Brooks"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Health Policy"
                        "fecha" => "1996"
                        "volumen" => "37"
                        "paginaInicial" => "53"
                        "paginaFinal" => "72"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10158943"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "UK Population Norms for EQ-5D&#46; Discussion Paper 172&#46; York United Kingdom&#58; Centre for Health Economics"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46; Kind"
                            1 => "G&#46; Hardman"
                            2 => "S&#46; Macran"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:2 [
                        "fecha" => "1999"
                        "editorial" => "University of York"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Modelling valuations for EuroQol health states"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46; Dolan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Medical Care"
                        "fecha" => "1997"
                        "volumen" => "35"
                        "paginaInicial" => "1095"
                        "paginaFinal" => "1108"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9366889"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The estimation of a preference-based measure of health from the SF-36"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Brazier"
                            1 => "J&#46; Roberts"
                            2 => "M&#46; Deverill"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Journal of Health Economics"
                        "fecha" => "2002"
                        "volumen" => "21"
                        "paginaInicial" => "271"
                        "paginaFinal" => "292"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11939242"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "O sistema portugu&#234;s de valores do SF-6D"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46; Ferreira"
                            1 => "L&#46; Ferreira"
                            2 => "L&#46; Pereira"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Port Sa&#250;de P&#250;blica"
                        "fecha" => "2009"
                        "volumen" => "8"
                        "paginaInicial" => "7"
                        "paginaFinal" => "23"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation of impairment of health related quality of life in asthma&#58; development of a questionnaire for use in clinical trials"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "E&#46; Juniper"
                            1 => "G&#46; Guyatt"
                            2 => "R&#46; Epstein"
                            3 => "P&#46; Ferrie"
                            4 => "R&#46; Jaeschke"
                            5 => "T&#46; Hiller"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "1992"
                        "volumen" => "47"
                        "numero" => "2"
                        "paginaInicial" => "76"
                        "paginaFinal" => "83"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1549827"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Measuring quality of life in asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "E&#46; Juniper"
                            1 => "G&#46; Guyatt"
                            2 => "P&#46; Ferrie"
                            3 => "L&#46; Griffith"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm/147.4.832"
                      "Revista" => array:7 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1993"
                        "volumen" => "147"
                        "paginaInicial" => "832"
                        "paginaFinal" => "838"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8466117"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0002937807022673"
                          "estado" => "S300"
                          "issn" => "00029378"
                        ]
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                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Asthma Quality of Life Questionnaires &#40;AQLQ&#44; AQLQ&#40;S&#41; MiniAQLQ and Acute AQLQ&#41; &#8211; Background&#44; Administration and Analysis"
                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:1 [
                            0 => "E&#46; Juniper"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:2 [
                        "fecha" => "2005"
                        "editorial" => "QOL Technologies"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Validation of a standardized version of the Asthma Quality of Life Questionnaire"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "E&#46; Juniper"
                            1 => "A&#46; Buist"
                            2 => "F&#46; Cox"
                            3 => "P&#46; Ferrie"
                            4 => "D&#46; King"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1999"
                        "volumen" => "115"
                        "paginaInicial" => "1265"
                        "paginaFinal" => "1270"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10334138"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Brief questionnaires for patient-reported out-comes in asthma&#58; Validation and usefulness in a primary care setting"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "P&#46;-O&#46; Ehrs"
                            1 => "M&#46; Nokela"
                            2 => "B&#46; St&#228;llberg"
                            3 => "P&#46; Hjemdahl"
                            4 => "E&#46;W&#46; Jonsson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.129.4.925"
                      "Revista" => array:7 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2006"
                        "volumen" => "129"
                        "numero" => "4"
                        "paginaInicial" => "925"
                        "paginaFinal" => "932"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16608940"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Determining a minimal important change in a disease-specific quality of life questionnaire"
                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:4 [
                            0 => "E&#46; Juniper"
                            1 => "G&#46; Guyatt"
                            2 => "A&#46; Willan"
                            3 => "L&#46; Griffith"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "J Clin Epidemiol"
                        "fecha" => "1994"
                        "volumen" => "47"
                        "numero" => "1"
                        "paginaInicial" => "81"
                        "paginaFinal" => "87"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8283197"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
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              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Development and validation of a questionnaire to measure asthma control"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "E&#46; Juniper"
                            1 => "P&#46; O&#8217;Byrne"
                            2 => "G&#46; Guyatt"
                            3 => "P&#46; Ferrie"
                            4 => "D&#46; King"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "1999"
                        "volumen" => "14"
                        "paginaInicial" => "902"
                        "paginaFinal" => "907"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10573240"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
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                0 => array:1 [
                  "referenciaCompleta" => "I NSA&#44; INE&#46; 4&#46;&#176; Inqu&#233;rito Nacional de Sa&#250;de 2005&#47;2006&#46; Lisboa&#58; Instituto Nacional de Sa&#250;de Dr&#46; Ricardo Jorge e Instituto Nacional de Estat&#237;stica&#44; 2006&#46;"
                ]
              ]
            ]
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              "identificador" => "bib23"
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Measuring self-reported population health&#58; an international perspective based on EQ-5D"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46; Szende"
                            1 => "A&#46; Williams"
                          ]
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                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "2004"
                        "editorial" => "SpringMed Publishing"
                        "editorialLocalizacion" => "Hungary"
                      ]
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                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Qualidade de vida em doentes com artrite reumat&#243;ide"
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                          "etal" => false
                          "autores" => array:3 [
                            0 => "L&#46; Ferreira"
                            1 => "P&#46; Ferreira"
                            2 => "R&#46; Baleiro"
                          ]
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                        "tituloSerie" => "Acta Reumatol&#243;gica Portuguesa"
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                        "numero" => "3"
                        "paginaInicial" => "341"
                        "paginaFinal" => "342"
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              ]
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Qualidade de vida em doentes com cataratas"
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                          "etal" => false
                          "autores" => array:2 [
                            0 => "L&#46; Ferreira"
                            1 => "P&#46; Ferreira"
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                    ]
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Oftalmologia"
                        "fecha" => "2008"
                        "volumen" => "32"
                        "paginaInicial" => "159"
                        "paginaFinal" => "175"
                      ]
                    ]
                  ]
                ]
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            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26&#46;"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Is the asthma quality of life questionnaire a useful measure for low-income asthmatics&#63;"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "N&#46; Leidy"
                            1 => "K&#46; Chan"
                            2 => "C&#46; Coughlin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Respir Crit Care Med"
                        "fecha" => "1998"
                        "volumen" => "158"
                        "paginaInicial" => "1082"
                        "paginaFinal" => "1090"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Quality of life in allergic rhinitis and asthma &#8211; A population-based study of young adults"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
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                            1 => "C&#46; Neukirch"
                            2 => "R&#46; Liard"
                            3 => "F&#46; Neukirch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2000"
                        "volumen" => "162"
                        "paginaInicial" => "1291"
                        "paginaFinal" => "1396"
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib28"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical predictors of health-related quality of life depend on asthma severity"
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                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Moy"
                            1 => "E&#46; Israel"
                            2 => "S&#46; Weiss"
                            3 => "E&#46; Juniper"
                            4 => "L&#46; Dub&#233;"
                            5 => "J&#46; Drazen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.163.4.2008014"
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                        "paginaFinal" => "929"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11282767"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib29"
              "etiqueta" => "29&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characteristics of patients with asthma within a large HMO &#8211; A comparison by age and gender"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
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                            2 => "K&#46; Linton"
                            3 => "A&#46; Buist"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.157.1.9612063"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "1998"
                        "volumen" => "157"
                        "paginaInicial" => "123"
                        "paginaFinal" => "128"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9445289"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib30"
              "etiqueta" => "30&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Work life of persons with asthma&#44; rhinitis&#44; and COPD&#58; A study using a national&#44; population-based sample"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Yelin"
                            1 => "P&#46; Katz"
                            2 => "J&#46; Balmes"
                            3 => "L&#46; Trupin"
                            4 => "G&#46; Earnest"
                            5 => "M&#46; Eisner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/1745-6673-1-2"
                      "Revista" => array:5 [
                        "tituloSerie" => "Journal of Occupational Medicine and Toxicology"
                        "fecha" => "2006"
                        "volumen" => "1"
                        "paginaInicial" => "2"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16722563"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib31"
              "etiqueta" => "31&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Measuring the impact of asthma on quality of life in the Australian population AIHW Cat&#46; no&#46; ACM 3&#46;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Australian Institute of Health and Welfare"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
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                        "editorialLocalizacion" => "Canberra&#44; Australia"
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                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib32"
              "etiqueta" => "32&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Preference assessment in patients with asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "T&#46; Lee"
                            1 => "K&#46; Weiss"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1586/14737167.2015.1021689"
                      "Revista" => array:7 [
                        "tituloSerie" => "Expert Review of Pharmacoeconomics &#38; Outcomes Research"
                        "fecha" => "2002"
                        "volumen" => "2"
                        "numero" => "6"
                        "paginaInicial" => "607"
                        "paginaFinal" => "618"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25737028"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib33"
              "etiqueta" => "33&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Population norms for the MMSE in the very old Estimates based on longitudinal data"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:5 [
                            0 => "C&#46;D&#46;C&#46; Dufouil"
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                            2 => "L&#46; Chi"
                            3 => "T&#46; Dening"
                            4 => "E&#46; Paykel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Neurology"
                        "fecha" => "2000"
                        "volumen" => "55"
                        "numero" => "11"
                        "paginaInicial" => "1601"
                        "paginaFinal" => "1602"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11113211"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib34"
              "etiqueta" => "34&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Population norms and meaningful differences for the assessment of quality of life &#40;AQoL&#41; measure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46; Hawthorne"
                            1 => "R&#46; Osborne"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Australian New Zealand Journal of Public Health"
                        "fecha" => "2005"
                        "volumen" => "29"
                        "numero" => "2"
                        "paginaInicial" => "136"
                        "paginaFinal" => "142"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib35"
              "etiqueta" => "35&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Interpreting the WHOQOL-Bref&#58; Preliminary population norms and effect sizes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46; Hawthorne"
                            1 => "H&#46; Herrman"
                            2 => "B&#46; Murphy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Social Indicators Research"
                        "fecha" => "2006"
                        "volumen" => "77"
                        "numero" => "1"
                        "paginaInicial" => "37"
                        "paginaFinal" => "59"
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib36"
              "etiqueta" => "36&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The SF36 version 2&#58; critical analyses of population weights&#44; scoring algorithms and population norms"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "G&#46; Hawthorne"
                            1 => "R&#46; Osborne"
                            2 => "A&#46; Taylor"
                            3 => "J&#46; Sansoni"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s11136-006-9154-4"
                      "Revista" => array:6 [
                        "tituloSerie" => "Quality of Life Research"
                        "fecha" => "2007"
                        "volumen" => "16"
                        "paginaInicial" => "661"
                        "paginaFinal" => "673"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17268926"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bib37"
              "etiqueta" => "37&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Quality of life in the Danish general population-normative data and validity of WHOQOL-BREF using rasch and item response theory models"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "V&#46; Noerholm"
                            1 => "M&#46; Groenvold"
                            2 => "T&#46; Watt"
                            3 => "J&#46; Bjorner"
                            4 => "N&#46;-A&#46; Rasmussen"
                            5 => "P&#46; Bech"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1023/B:QURE.0000018485.05372.d6"
                      "Revista" => array:6 [
                        "tituloSerie" => "Quality of Life Research"
                        "fecha" => "2004"
                        "volumen" => "13"
                        "paginaInicial" => "531"
                        "paginaFinal" => "540"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15085925"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            37 => array:3 [
              "identificador" => "bib38"
              "etiqueta" => "38&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Developing and testing symptom-based outcome measures"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "N&#46; Steen"
                            1 => "E&#46; McColl"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:5 [
                        "titulo" => "Health outcome measures in primary and out-patient care"
                        "paginaInicial" => "23"
                        "paginaFinal" => "44"
                        "edicion" => "1st ed"
                        "serieFecha" => "1996"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            38 => array:3 [
              "identificador" => "bib39"
              "etiqueta" => "39&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Discriminative aspects of two generic and two asthma-specific instruments&#58; relation with symptoms&#44; bronchodilator use and lung function in patients with mild asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "T&#46; Van der Molen"
                            1 => "D&#46; Postma"
                            2 => "A&#46; Schreurs"
                            3 => "H&#46; Bosveld"
                            4 => "M&#46; Sears"
                            5 => "R&#46; Meyboom"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Quality of Life Research"
                        "fecha" => "1997"
                        "volumen" => "6"
                        "paginaInicial" => "353"
                        "paginaFinal" => "361"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9248317"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            39 => array:3 [
              "identificador" => "bib40"
              "etiqueta" => "40&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Measuring and valuing health benefits for economic evaluation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46; Brazier"
                            1 => "J&#46; Ratcliffe"
                            2 => "J&#46; Salomon"
                            3 => "A&#46; Tsuchiya"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "2007"
                        "editorial" => "Oxford University Press"
                        "editorialLocalizacion" => "Oxford"
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                    ]
                  ]
                ]
              ]
            ]
            40 => array:3 [
              "identificador" => "bib41"
              "etiqueta" => "41&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Furlong W&#44; Feeny D&#44; Torrance G&#44; Barr R&#44; Horsman J&#46; Guide to design and development health-state utility instrumentation&#44; Working Paper Series&#46; Ontario&#44; Canad&#225;&#58; McMaster University Press&#44; 1990&#46;"
                ]
              ]
            ]
            41 => array:3 [
              "identificador" => "bib42"
              "etiqueta" => "42&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Measurement of health state utilities for economic appraisal"
                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:1 [
                            0 => "G&#46; Torrance"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Journal of Health Economics"
                        "fecha" => "1986"
                        "volumen" => "5"
                        "paginaInicial" => "1"
                        "paginaFinal" => "30"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10311607"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0002937808020541"
                          "estado" => "S300"
                          "issn" => "00029378"
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                      ]
                    ]
                  ]
                ]
              ]
            ]
            42 => array:3 [
              "identificador" => "bib43"
              "etiqueta" => "43&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The measurement of health related quality of life for use in resource allocation decisions in health care"
                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46; Dolan"
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                        ]
                      ]
                    ]
                  ]
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                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Handbook of health economics&#46;"
                        "paginaInicial" => "1723"
                        "paginaFinal" => "1760"
                        "serieFecha" => "2000"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            43 => array:3 [
              "identificador" => "bib44"
              "etiqueta" => "44&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outputs measures and valuation in health"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46; Dolan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Economic evaluation in health care &#8211; Merging theory with practice"
                        "paginaInicial" => "46"
                        "paginaFinal" => "67"
                        "serieFecha" => "2001"
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib45"
              "etiqueta" => "45&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Using the EuroQol 5-D in the Catalan general population&#58; Feasibility and construct validity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "X&#46; Badia"
                            1 => "A&#46; Schiaffino"
                            2 => "J&#46;M&#46;H&#46; Alonso"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Quality of Life Research"
                        "fecha" => "1998"
                        "volumen" => "7"
                        "paginaInicial" => "311"
                        "paginaFinal" => "322"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9610215"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
            ]
            45 => array:3 [
              "identificador" => "bib46"
              "etiqueta" => "46&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Swedish population health-related quality of life results using the EQ-5D"
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                          "etal" => false
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                            0 => "K&#46; Burstr&#246;m"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
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                      "titulo" => "EuroQol&#58; health-related quality of life measurement Valuation of health sates by the general public in Norway3"
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                        "paginaFinal" => "36"
                        "link" => array:1 [
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Vol. 16. Issue 1.
Pages 23-55 (January - February 2010)
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Vol. 16. Issue 1.
Pages 23-55 (January - February 2010)
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Quality of life in asthma patients
Qualidade de vida em doentes com asma
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949
Lara Noronha Ferreira1,2,
Corresponding author
Lnferrei@ualg.pt

Correspondence to/Correspondência para: Escola Superior de Gestão, Hotelaria e Turismo Universidade do Algarve Campus da Penha 8005-139 Faro Portugal Telefone: +351 289800114 Fax: +351 289888404.
, Ulisses Brito3, Pedro Lopes Ferreira2,4
1 Professora Adjunta – Escola Superior de Gestão, Hotelaria e Turismo da Universidade do Algarve (ESGHT-UAlg)/Adjunct Professor – School of Management, Hospitality and Tourism, University of the Algarve
2 Centro de Estudos e Investigação em Saúde da Universidade de Coimbra (CEISUC)/Centre for Health Studies & Research, University of Coimbra
3 Director do Serviço de Pneumologia do Hospital de Faro, EPE /Director, Pulmonology Unit, Central Hospital of Faro
4 Professor Associado com Agregação – Faculdade de Economia da Universidade de Coimbra (FE-UC)/Associate Professor – Faculty of Economics, University of Coimbra
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Abstract

In this paper we present a study whose main aim is the measurement of the Health Related Quality of Life (HRQoL) of patients with asthma and the presentation of a first draft of normative values as measured by the SF-6D for asthma patients. In addition, we investigate how far non-disease-specific HRQoL measures can distinguish groups in terms of sociodemographic characteristics.

The Portuguese versions of the EQ-5D, SF-6D, AQLQ(S) and ACQ were administered using personal interviews to a representative sample of the Portuguese population with asthma.

Most of the individuals did not report significant problems in the dimensions used, with the exception of the physical functioning, where individuals reported moderate limitations. The mean utility value was 0.86. Male gender, young, single, individuals with high educational attainment level, employed, individuals with high income and those residing in urban areas reported higher utility levels. As expected, those who were in a severe stadium of the disease reported lower mean utility levels than those who were in a less severe stadium of the disease. Normative values for the SF-6D were computed for patients with asthma by gender, age, marital status, educational attainment level, employment status, area of residence and average monthly net income.

The preference-based measures used in this study distinguish patient groups with asthma in terms of socio-demographic groups. The normative values can be used in economic evaluation and clinical studies as they incorporate patients’ preferences and translate the value attributed to patients’ health state.

Key-words:
Asthma
health related quality of life
normative data
preference-based measures of health related quality of life
SF-6D
Resumo

Neste artigo é descrito um estudo, cujo objectivo é a medição da qualidade de vida relacionada com a saúde (QdVRS) de doentes com asma e a apresentação de uma primeira aproximação aos valores normativos, com base no SF-6D, para aquele tipo de doentes. Pretende-se ainda averiguar a capacidade de medidas genéricas de medição da QdVRS distinguirem grupos em termos de características sociodemográficas. Aplicaram-se, por entrevista pessoal, as versões portuguesas do EQ-5D, do SF-6D, do AQLQ(S) e do ACQ a uma amostra representativa da população portuguesa com asma.

A maioria dos indivíduos não apresentou problemas significativos nas dimensões medidas, excepto na função física, onde os indivíduos reportaram limitações moderadas. Em média, os inquiridos apresentam valores de utilidade de 0,86. Os homens, os mais jovens, os solteiros, os indivíduos com habilitações literárias mais elevadas, os empregados, os indivíduos com rendimentos mais elevados e aqueles que residiam em zonas urbanas foram os que reportaram níveis de utilidade mais elevados. Por outro lado, os indivíduos que se encontravam num estádio mais avançado da doença reportaram, como era de esperar, níveis médios de utilidade inferiores aos dos que se encontravam num estádio menos grave da doença. Foram obtidos valores normativos para o SF-6D para doentes com asma por género, grupo etário, estado civil, habilitações literárias, situação profissional, local de residência e rendimento médio mensal líquido.

As medidas de utilidade baseadas em preferências utilizadas neste estudo discriminam adequadamente grupos de doentes com asma, de acordo com grupos sociodemográficos. Os valores normativos obtidos podem ser usados em estudos de avaliação económica e estudos clínicos, uma vez que incorporam as preferências dos doentes e traduzem a utilidade atribuída ao seu estado de saúde.

Palavras-chave:
Asma
instrumentos de medição da qualidade de vida relacionada com a saúde baseados em preferências
qualidade de vida relacionada com a saúde
SF-6D
valores normativos
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Bibliography/Bibliografia
[1.]
J.L. Plácido.
A asma a nível nacional e mundial: Perspectivas actuais e tendências de evolução.
Rev Por Clín Geral, 20 (2004), pp. 583-587
[2.]
T. Schermer, B. Thoonem, G. Van den Boom, R. Akkermans, R. Grol, H. Folgering, et al.
Randomized controlled economic evaluation of asthma self-management in primary health care.
Am J Respir Crit Care Med, 166 (2002), pp. 1062-1072
[3.]
A. Szende, K. Svensson, E. Ståhl, A. Mészáros, G. Berta.
Psychometric and utility-based measures of health status of asthmatic patients with different disease control level.
Pharmacoeconomics, 22 (2004), pp. 537-547
[4.]
E. Juniper, G. Norman, F. Cox, J. Roberts.
Comparison of the standard gamble, rating scale, AQLQ and SF-36 for measuring quality of life in asthma.
Eur Respir J, 18 (2001), pp. 38-44
[5.]
H. McTaggart-Cowan, C. Marra, Y. Yang, J. Brazier, J. Kopec, J. FitzGerald, et al.
The validity of generic and condition-specific preference-based instruments: the ability to discriminate asthma control status.
Quality of Life Research, 17 (2008), pp. 453-462
[6.]
M. Rutten-van Mölken, F. Custers, E. Van Doorslaer, C. Jansen, L. Heurman, F. Maesen, et al.
Comparison of performance of four instruments in evaluating the effects of salmeterol on asthma quality of life.
Eur Respir J, 8 (1995), pp. 888-898
[7.]
W. Vollmer, L. Markson, E. O’Connor, L. Sanocki, L. Fitterman, M. Berger, et al.
Association of asthma control with health care utilization and quality of life.
Am J Respir Crit Care Med, 160 (1999), pp. 1647-1652
[8.]
P. Ferreira, L. Ferreira.
A medição de preferências em saúde na população portuguesa.
Rev Port Saúde Pública, 24 (2006), pp. 5-14
[9.]
W. Greiner, T. Weijnen, M. Nieuwenhuizen, S. Oppe, X. Badia, J. Busschbach, et al.
A single European currency for EQ-5D health states: Results from a six-country study.
European Journal of Health Economics, 4 (2003), pp. 222-231
[10.]
R. Brooks.
EuroQol: the current state of play.
Health Policy, 37 (1996), pp. 53-72
[11.]
P. Kind, G. Hardman, S. Macran.
UK Population Norms for EQ-5D. Discussion Paper 172. York United Kingdom: Centre for Health Economics.
University of York, (1999),
[12.]
P. Dolan.
Modelling valuations for EuroQol health states.
Medical Care, 35 (1997), pp. 1095-1108
[13.]
J. Brazier, J. Roberts, M. Deverill.
The estimation of a preference-based measure of health from the SF-36.
Journal of Health Economics, 21 (2002), pp. 271-292
[14.]
P. Ferreira, L. Ferreira, L. Pereira.
O sistema português de valores do SF-6D.
Rev Port Saúde Pública, 8 (2009), pp. 7-23
[15.]
E. Juniper, G. Guyatt, R. Epstein, P. Ferrie, R. Jaeschke, T. Hiller.
Evaluation of impairment of health related quality of life in asthma: development of a questionnaire for use in clinical trials.
Thorax, 47 (1992), pp. 76-83
[16.]
E. Juniper, G. Guyatt, P. Ferrie, L. Griffith.
Measuring quality of life in asthma.
Am Rev Respir Dis, 147 (1993), pp. 832-838
[17.]
E. Juniper.
Asthma Quality of Life Questionnaires (AQLQ, AQLQ(S) MiniAQLQ and Acute AQLQ) – Background, Administration and Analysis.
QOL Technologies, (2005),
[18.]
E. Juniper, A. Buist, F. Cox, P. Ferrie, D. King.
Validation of a standardized version of the Asthma Quality of Life Questionnaire.
Chest, 115 (1999), pp. 1265-1270
[19.]
P.-O. Ehrs, M. Nokela, B. Ställberg, P. Hjemdahl, E.W. Jonsson.
Brief questionnaires for patient-reported out-comes in asthma: Validation and usefulness in a primary care setting.
Chest, 129 (2006), pp. 925-932
[20.]
E. Juniper, G. Guyatt, A. Willan, L. Griffith.
Determining a minimal important change in a disease-specific quality of life questionnaire.
J Clin Epidemiol, 47 (1994), pp. 81-87
[21.]
E. Juniper, P. O’Byrne, G. Guyatt, P. Ferrie, D. King.
Development and validation of a questionnaire to measure asthma control.
Eur Respir J, 14 (1999), pp. 902-907
[22.]
I NSA, INE. 4.° Inquérito Nacional de Saúde 2005/2006. Lisboa: Instituto Nacional de Saúde Dr. Ricardo Jorge e Instituto Nacional de Estatística, 2006.
[23.]
A. Szende, A. Williams.
Measuring self-reported population health: an international perspective based on EQ-5D.
SpringMed Publishing, (2004),
[24.]
L. Ferreira, P. Ferreira, R. Baleiro.
Qualidade de vida em doentes com artrite reumatóide.
Acta Reumatológica Portuguesa, 33 (2008), pp. 341-342
[25.]
L. Ferreira, P. Ferreira.
Qualidade de vida em doentes com cataratas.
Oftalmologia, 32 (2008), pp. 159-175
[26.]
N. Leidy, K. Chan, C. Coughlin.
Is the asthma quality of life questionnaire a useful measure for low-income asthmatics?.
J Respir Crit Care Med, 158 (1998), pp. 1082-1090
[27.]
B. Leynaert, C. Neukirch, R. Liard, F. Neukirch.
Quality of life in allergic rhinitis and asthma – A population-based study of young adults.
Am J Respir Crit Care Med, 162 (2000), pp. 1291-1396
[28.]
M. Moy, E. Israel, S. Weiss, E. Juniper, L. Dubé, J. Drazen, et al.
Clinical predictors of health-related quality of life depend on asthma severity.
Am J Respir Crit Care Med, 163 (2001), pp. 924-929
[29.]
M. Osborne, W. Vollmer, K. Linton, A. Buist.
Characteristics of patients with asthma within a large HMO – A comparison by age and gender.
Am J Respir Crit Care Med, 157 (1998), pp. 123-128
[30.]
E. Yelin, P. Katz, J. Balmes, L. Trupin, G. Earnest, M. Eisner, et al.
Work life of persons with asthma, rhinitis, and COPD: A study using a national, population-based sample.
Journal of Occupational Medicine and Toxicology, 1 (2006), pp. 2
[31.]
Australian Institute of Health and Welfare.
Measuring the impact of asthma on quality of life in the Australian population AIHW Cat. no. ACM 3..
Australian Institute of Health and Welfare, (2004),
[32.]
T. Lee, K. Weiss.
Preference assessment in patients with asthma.
Expert Review of Pharmacoeconomics & Outcomes Research, 2 (2002), pp. 607-618
[33.]
C.D.C. Dufouil, C. Brayne, L. Chi, T. Dening, E. Paykel, et al.
Population norms for the MMSE in the very old Estimates based on longitudinal data.
Neurology, 55 (2000), pp. 1601-1602
[34.]
G. Hawthorne, R. Osborne.
Population norms and meaningful differences for the assessment of quality of life (AQoL) measure.
Australian New Zealand Journal of Public Health, 29 (2005), pp. 136-142
[35.]
G. Hawthorne, H. Herrman, B. Murphy.
Interpreting the WHOQOL-Bref: Preliminary population norms and effect sizes.
Social Indicators Research, 77 (2006), pp. 37-59
[36.]
G. Hawthorne, R. Osborne, A. Taylor, J. Sansoni.
The SF36 version 2: critical analyses of population weights, scoring algorithms and population norms.
Quality of Life Research, 16 (2007), pp. 661-673
[37.]
V. Noerholm, M. Groenvold, T. Watt, J. Bjorner, N.-A. Rasmussen, P. Bech.
Quality of life in the Danish general population-normative data and validity of WHOQOL-BREF using rasch and item response theory models.
Quality of Life Research, 13 (2004), pp. 531-540
[38.]
N. Steen, E. McColl.
Developing and testing symptom-based outcome measures.
Health outcome measures in primary and out-patient care, 1st ed, pp. 23-44
[39.]
T. Van der Molen, D. Postma, A. Schreurs, H. Bosveld, M. Sears, R. Meyboom, et al.
Discriminative aspects of two generic and two asthma-specific instruments: relation with symptoms, bronchodilator use and lung function in patients with mild asthma.
Quality of Life Research, 6 (1997), pp. 353-361
[40.]
J. Brazier, J. Ratcliffe, J. Salomon, A. Tsuchiya.
Measuring and valuing health benefits for economic evaluation.
Oxford University Press, (2007),
[41.]
Furlong W, Feeny D, Torrance G, Barr R, Horsman J. Guide to design and development health-state utility instrumentation, Working Paper Series. Ontario, Canadá: McMaster University Press, 1990.
[42.]
G. Torrance.
Measurement of health state utilities for economic appraisal.
Journal of Health Economics, 5 (1986), pp. 1-30
[43.]
P. Dolan.
The measurement of health related quality of life for use in resource allocation decisions in health care.
Handbook of health economics., pp. 1723-1760
[44.]
P. Dolan.
Outputs measures and valuation in health.
Economic evaluation in health care – Merging theory with practice, pp. 46-67
[45.]
X. Badia, A. Schiaffino, J.M.H. Alonso.
Using the EuroQol 5-D in the Catalan general population: Feasibility and construct validity.
Quality of Life Research, 7 (1998), pp. 311-322
[46.]
K. Burström, M. Johannesson, F. Diderichsen.
Swedish population health-related quality of life results using the EQ-5D.
Quality of Life Research, 10 (2001), pp. 621-635
[47.]
E. Nord.
EuroQol: health-related quality of life measurement Valuation of health sates by the general public in Norway3.
Health Policy, 18 (1991), pp. 25-36
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