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        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Respiratory support strategies for the preterm newborn have been the subject of intense research&#46;</p> <span class="elsevierStyleSectionTitle">Aim</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">To survey neonatal respiratory support practices in Portugal and to determine whether they reflect evidence from randomised trials&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Questionnaires were given out to 31 Portuguese neonatal units to determine the types of ventilators&#44; modes of ventilation&#44; lung function monitoring&#44; use of exogenous surfactant&#44; oxygen saturation levels used and the prevalence of chronic lung disease in the preterm newborn&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">There was a 94&#37; response rate&#46; Draeger babylog was the most frequently used ventilator in neonates&#46; Twelve &#40;41&#37;&#41; units prefer to use early nasal continuous positive airway pressure &#40;NCPAP&#41; whenever possible&#46; Triggered ventilation is the choice of invasive ventilation in 24 &#40;83&#37;&#41; units &#40;SIMV&#44; SIPPV&#44; PSV&#41;&#59; four &#40;14&#37;&#41; units have high frequency oscillation ventilation&#46; SIMV is the most frequent &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>13&#44; 45&#37;&#41; weaning mode&#46; Exogenous surfactant is used as prophylactic in 12 &#40;41&#37;&#41; units&#46; All units use lung function measurements to aid choice of ventilator settings and five &#40;17&#37;&#41; units monitor PaCO<span class="elsevierStyleInf">2</span> &#40;transcutaneous &#61; 3&#59; capnometry &#61; 2&#41;&#46; Seventeen &#40;59&#37;&#41; units allow oxygen saturation levels from 90&#37; to 95&#37; in infants with respiratory distress syndrome and 15 &#40;52&#37;&#41; levels from 85&#37; to 90&#37; in infants with chronic lung disease&#46; Prevalence of chronic lung disease of prematurity ranged from 0&#37; to 75&#37; &#40;median&#58; 10&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Many respiratory strategies for extremely low birth weight infants reflect the result of large randomised trials&#46; More effective methods may be required to encourage the use of early NCPAP preferably with binasal prongs&#44; the use of SIPPV as the main weaning mode&#44; the use of volume targeted ventilation and a more judicious use of exogenous surfactant in order to ensure evidence&#8211;based practice&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introdu&#231;&#227;o</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">As estrat&#233;gias de suporte ventilat&#243;rio utilizadas no rec&#233;m-nascido t&#234;m sido motivo de grande investiga&#231;&#227;o&#46;</p> <span class="elsevierStyleSectionTitle">Objectivos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Avaliar as pr&#225;ticas de suporte ventilat&#243;rio nas unidades de neonatologia nacionais utilizadas na assist&#234;ncia ao rec&#233;m-nascido de extremo baixo peso e avaliar se est&#227;o em conformidade com a pr&#225;tica baseada na evid&#234;ncia&#46;</p> <span class="elsevierStyleSectionTitle">M&#233;todos</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Foi enviado&#44; por via electr&#243;nica&#44; a 31 unidades de neonatologia nacionais&#44; um inqu&#233;rito sobre tipos de ventiladores&#44; modos de ventila&#231;&#227;o&#44; monitoriza&#231;&#227;o da fun&#231;&#227;o pulmonar&#44; valores de satura&#231;&#227;o de oxig&#233;nio permitidos e preval&#234;ncia de doen&#231;a pulmonar cr&#243;nica da prematuridade&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A percentagem de resposta foi de 94&#37;&#46; O modelo de ventilador Draeger Babylog &#233; o mais utilizado&#46; Doze &#40;41&#37;&#41; unidades preconizam o NCPAP precoce&#46; A ventila&#231;&#227;o sincronizada &#233; de elei&#231;&#227;o em 24 &#40;83&#37;&#41; unidades &#40;SIMV&#44; SIPPV&#44; PSV&#41; e 4 &#40;14&#37;&#41; t&#234;m possibilidade de ventila&#231;&#227;o por alta frequ&#234;ncia oscilat&#243;ria&#46; O modo ventilat&#243;rio SIMV &#233; o mais utilizado &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>13&#44; 45&#37;&#41; no &#8220;desmame&#8221; ventilat&#243;rio&#46; O surfactante ex&#243;geno &#233; usado preferencialmente de modo profil&#225;ctico em 12 &#40;41&#37;&#41; unidades&#46; Todas as unidades usam valores de fun&#231;&#227;o respirat&#243;ria no ajuste dos par&#226;metros ventilat&#243;rios e cinco &#40;17&#37;&#41; utilizam monitoriza&#231;&#227;o cont&#237;nua da PaCO<span class="elsevierStyleInf">2</span>&#58; medi&#231;&#227;o transcut&#226;nea &#61; 3&#59; capnometria &#61; 2&#46; Dezassete &#40;59&#37;&#41; unidades utilizam valores de satura&#231;&#227;o de oxig&#233;nio de 90&#37;&#8211;95&#37; na doen&#231;a das membranas hialinas e 15 &#40;52&#37;&#41; utilizam valores de 85&#37;&#8211;90&#37; na doen&#231;a pulmonar cr&#243;nica da prematuridade&#46; A preval&#234;ncia de doen&#231;a pulmonar cr&#243;nica da prematuridade variou entre os 0&#37; e os 75&#37; &#40;mediana&#58; 10&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclus&#227;o</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">As estrat&#233;gias de suporte ventilat&#243;rio usadas nas unidades portuguesas reflectem&#44; em parte&#44; a evid&#234;ncia de estudos multic&#234;ntricos aleatorizados&#46; &#201; necess&#225;rio mais investimento no uso de NCPAP precoce&#44; preferencialmente com <span class="elsevierStyleItalic">prongs</span> binasal&#44; uso do modo SIPPV no &#8220;desmame&#8221; ventilat&#243;rio&#44; uso de estrat&#233;gias ventilat&#243;rias com volumes correntes optimizados e utiliza&#231;&#227;o criteriosa de surfactante ex&#243;geno&#44; de modo a assegurar a pr&#225;tica baseada na evid&#234;ncia&#46;</p>"
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Vol. 15. Issue 6.
Pages 1043-1071 (November - December 2009)
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Vol. 15. Issue 6.
Pages 1043-1071 (November - December 2009)
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Respiratory support strategies for the preterm newborn – National survey 2008
Estratégias de suporte ventilatório no recém-nascido pré-termo – Inquérito nacional (2008)
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845
Gustavo Rocha
,1,
Corresponding author
gusrocha@oninet.pt

Correspondence to/Correspondência: Serviço de Neonatologia, Departamento de Pediatria, Hospital de São João, Piso 2, Alameda Professor Hernâni Monteiro, 4202-451 Porto, Telefone: 225512100, extensão/extension 1949, Fax: +225512273.
, Joana Saldanha
,2
, Israel Macedo
,3
, Augusta Areias
,4
¿ Comissão de Investigação Científica da Secção de Neonatologia da Sociedade Portuguesa de Pediatria/Portuguese Society of Paediatrics Neonatology Section Scientific Research Committee
1. Serviço de Neonatologia, Hospital de São João, Porto/Neonatal Unit, Hospital de São João, Porto
2. Unidade de Neonatologia, Hospital de Santa Maria, Lisboa/Neonatal Unit, Hospital de Santa Maria, Lisboa
3. Unidade de Neonatologia, Maternidade Dr. Alfredo da Costa, Lisboa/Neonatal Unit, Maternidade Dr. Alfredo da Costa, Lisboa
4. Unidade de Neonatologia, Maternidade Júlio Dinis, Centro Hospitalar do Porto, Porto/Neonatal Unit, Maternidade Júlio Dinis, Centro Hospitalar do Porto, Porto
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Abstract
Background

Respiratory support strategies for the preterm newborn have been the subject of intense research.

Aim

To survey neonatal respiratory support practices in Portugal and to determine whether they reflect evidence from randomised trials.

Methods

Questionnaires were given out to 31 Portuguese neonatal units to determine the types of ventilators, modes of ventilation, lung function monitoring, use of exogenous surfactant, oxygen saturation levels used and the prevalence of chronic lung disease in the preterm newborn.

Results

There was a 94% response rate. Draeger babylog was the most frequently used ventilator in neonates. Twelve (41%) units prefer to use early nasal continuous positive airway pressure (NCPAP) whenever possible. Triggered ventilation is the choice of invasive ventilation in 24 (83%) units (SIMV, SIPPV, PSV); four (14%) units have high frequency oscillation ventilation. SIMV is the most frequent (n=13, 45%) weaning mode. Exogenous surfactant is used as prophylactic in 12 (41%) units. All units use lung function measurements to aid choice of ventilator settings and five (17%) units monitor PaCO2 (transcutaneous = 3; capnometry = 2). Seventeen (59%) units allow oxygen saturation levels from 90% to 95% in infants with respiratory distress syndrome and 15 (52%) levels from 85% to 90% in infants with chronic lung disease. Prevalence of chronic lung disease of prematurity ranged from 0% to 75% (median: 10).

Conclusions

Many respiratory strategies for extremely low birth weight infants reflect the result of large randomised trials. More effective methods may be required to encourage the use of early NCPAP preferably with binasal prongs, the use of SIPPV as the main weaning mode, the use of volume targeted ventilation and a more judicious use of exogenous surfactant in order to ensure evidence–based practice.

Key-words:
Newborn
ventilation
chronic lung disease of prematurity
respiratory distress syndrome
oxygen saturation
Resumo
Introdução

As estratégias de suporte ventilatório utilizadas no recém-nascido têm sido motivo de grande investigação.

Objectivos

Avaliar as práticas de suporte ventilatório nas unidades de neonatologia nacionais utilizadas na assistência ao recém-nascido de extremo baixo peso e avaliar se estão em conformidade com a prática baseada na evidência.

Métodos

Foi enviado, por via electrónica, a 31 unidades de neonatologia nacionais, um inquérito sobre tipos de ventiladores, modos de ventilação, monitorização da função pulmonar, valores de saturação de oxigénio permitidos e prevalência de doença pulmonar crónica da prematuridade.

Resultados

A percentagem de resposta foi de 94%. O modelo de ventilador Draeger Babylog é o mais utilizado. Doze (41%) unidades preconizam o NCPAP precoce. A ventilação sincronizada é de eleição em 24 (83%) unidades (SIMV, SIPPV, PSV) e 4 (14%) têm possibilidade de ventilação por alta frequência oscilatória. O modo ventilatório SIMV é o mais utilizado (n=13, 45%) no “desmame” ventilatório. O surfactante exógeno é usado preferencialmente de modo profiláctico em 12 (41%) unidades. Todas as unidades usam valores de função respiratória no ajuste dos parâmetros ventilatórios e cinco (17%) utilizam monitorização contínua da PaCO2: medição transcutânea = 3; capnometria = 2. Dezassete (59%) unidades utilizam valores de saturação de oxigénio de 90%–95% na doença das membranas hialinas e 15 (52%) utilizam valores de 85%–90% na doença pulmonar crónica da prematuridade. A prevalência de doença pulmonar crónica da prematuridade variou entre os 0% e os 75% (mediana: 10).

Conclusão

As estratégias de suporte ventilatório usadas nas unidades portuguesas reflectem, em parte, a evidência de estudos multicêntricos aleatorizados. É necessário mais investimento no uso de NCPAP precoce, preferencialmente com prongs binasal, uso do modo SIPPV no “desmame” ventilatório, uso de estratégias ventilatórias com volumes correntes optimizados e utilização criteriosa de surfactante exógeno, de modo a assegurar a prática baseada na evidência.

Palavras-chave:
Recém-nascido
ventilação
doença pulmonar crónica da prematuridade
doença das membranas hialinas
saturação de oxigénio
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