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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">In recent years non-invasive ventilation &#40;NIV&#41; as become a valuable therapeutic option in exacerbations of patients with chronic pulmonary obstructive disease&#46; Although widely used there is a paucity of information on weaning from NIV&#46;</p> <span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">We aimed to describe the performance of a weaning protocol based on progressive periods of NIV withdraw&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">During a one year period we performed NIV in 78 patients with acute exacerbation of chronic respiratory failure&#46; Weaning was considered in patients with 24 hours without acidosis and respiratory rate less than 25 cycles per minute&#46; Weaning was performed as following&#58; during the first 24 hours in each 3 hours&#44; one hour without NIV &#40;except during night period&#41;&#44; in the second day in each 3 hours&#44; two hours without NIV &#40;except during night period&#41; and in the third day NIV was used during the night period&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Sixty five patients began the weaning protocol&#46; Mean NIV time was 120&#44;9 hours &#40;17 to 192 hours&#41;&#46; No adverse effects were recorded in patients who began the weaning protocol&#46; All patients completed the weaning protocol with no re-institution of NIV or invasive ventilation during hospitalization&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">We report an excellent weaning success rate of NIV in patients with acute severe exacerbation of CRF&#46; Although our weaning protocol required 72 hours&#44; our results suggest that strategies based on periods with and with-out NIV are effective&#46; Weather similar less time consuming weaning strategies are effective&#44; merits investigation&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introdu&#231;&#227;o</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Nos &#250;ltimos anos&#44; a ventila&#231;&#227;o n&#227;o invasiva &#40;VNI&#41; tornou-se numa op&#231;&#227;o terap&#234;utica v&#225;lida nas exacerba&#231;&#245;es agudas de doentes com doen&#231;a pulmonar cr&#243;nica obstrutiva&#46; No entanto&#44; apesar de muito utilizada&#44; existe muito pouca informa&#231;&#227;o sobre o desmame deste modo ventilat&#243;rio&#46;</p> <span class="elsevierStyleSectionTitle">Objectivos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Descrever um protocolo de desmame baseado em per&#237;odos progressivos de descontinua&#231;&#227;o de VNI&#46;</p> <span class="elsevierStyleSectionTitle">M&#233;todos</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Durante um ano foram admitidos 78 doentes na nossa unidade para in&#237;cio de VNI devido a exacerba&#231;&#245;es agudas de doentes com doen&#231;a pulmonar cr&#243;nica obstrutiva&#46; O desmame de VNI era considerado em doentes que se apresentavam sem acidose e com frequ&#234;ncia respirat&#243;ria inferior a 25 ciclos por minuto&#46; O desmane era realizado da seguinte forma&#58; Durante as primeiras 24 horas&#44; em cada 3 horas de per&#237;odo diurno o doente estava sem VNI durante uma hora &#40;excepto &#224; noite&#41;&#59; no segundo dia&#44; em cada 3 horas o doente estava sem VNI durante 2 horas &#40;excepto &#224; noite&#41;&#44; e no terceiro dia a VNI era utilizada apenas em per&#237;odo nocturno&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Sessenta doentes iniciaram o protocolo de desmame&#46; O tempo m&#233;dio de VNI foi de 120&#46;9 horas &#40;17 a 192 horas&#41;&#46; N&#227;o houve registo de complica&#231;&#245;es nos doentes que iniciaram este protocolo&#46; Todos completaram o protocolo sem necessidade de reinstituir VNI ou ventila&#231;&#227;o invasiva durante o internamento&#46;</p> <span class="elsevierStyleSectionTitle">Conclus&#245;es</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Descrevemos uma taxa excelente de sucesso de desmame de VNI em doentes com exacerba&#231;&#245;es agudas de doentes com insufici&#234;ncia respirat&#243;ria cr&#243;nica&#46; Apesar de este protocolo implicar uma dura&#231;&#227;o de 72 horas&#44; os resultados sugerem que estrat&#233;gias baseadas em per&#237;odos com e sem VNI s&#227;o eficazes&#46; No entanto&#44; estrat&#233;gias menos demoradas merecem investiga&#231;&#227;o&#46;</p>"
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Vol. 14. Issue 1.
Pages 49-53 (January - February 2008)
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Vol. 14. Issue 1.
Pages 49-53 (January - February 2008)
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Weaning from non-invasive positive pressure ventilation: Experience with progressive periods of withdraw
Desmame de ventilação não invasiva: Experiência com períodos de descontinuação
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C. Damas2, C. Andrade1, J.P. Araújo1, J. Almeida1, P. Bettencourt1
1 Serviço de Medicina Interna do Hospital de São João, Porto
2 Serviço de Pneumologia do Hospital de São João, Porto Unidade I&D Cardiovascular do Porto Faculdade de Medicina da Universidade do Porto
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Abstract
Background

In recent years non-invasive ventilation (NIV) as become a valuable therapeutic option in exacerbations of patients with chronic pulmonary obstructive disease. Although widely used there is a paucity of information on weaning from NIV.

Objectives

We aimed to describe the performance of a weaning protocol based on progressive periods of NIV withdraw.

Methods

During a one year period we performed NIV in 78 patients with acute exacerbation of chronic respiratory failure. Weaning was considered in patients with 24 hours without acidosis and respiratory rate less than 25 cycles per minute. Weaning was performed as following: during the first 24 hours in each 3 hours, one hour without NIV (except during night period), in the second day in each 3 hours, two hours without NIV (except during night period) and in the third day NIV was used during the night period.

Results

Sixty five patients began the weaning protocol. Mean NIV time was 120,9 hours (17 to 192 hours). No adverse effects were recorded in patients who began the weaning protocol. All patients completed the weaning protocol with no re-institution of NIV or invasive ventilation during hospitalization.

Conclusions

We report an excellent weaning success rate of NIV in patients with acute severe exacerbation of CRF. Although our weaning protocol required 72 hours, our results suggest that strategies based on periods with and with-out NIV are effective. Weather similar less time consuming weaning strategies are effective, merits investigation.

Key-words:
Non-invasive ventilation
chronic respiratory failure
weaning
Resumo
Introdução

Nos últimos anos, a ventilação não invasiva (VNI) tornou-se numa opção terapêutica válida nas exacerbações agudas de doentes com doença pulmonar crónica obstrutiva. No entanto, apesar de muito utilizada, existe muito pouca informação sobre o desmame deste modo ventilatório.

Objectivos

Descrever um protocolo de desmame baseado em períodos progressivos de descontinuação de VNI.

Métodos

Durante um ano foram admitidos 78 doentes na nossa unidade para início de VNI devido a exacerbações agudas de doentes com doença pulmonar crónica obstrutiva. O desmame de VNI era considerado em doentes que se apresentavam sem acidose e com frequência respiratória inferior a 25 ciclos por minuto. O desmane era realizado da seguinte forma: Durante as primeiras 24 horas, em cada 3 horas de período diurno o doente estava sem VNI durante uma hora (excepto à noite); no segundo dia, em cada 3 horas o doente estava sem VNI durante 2 horas (excepto à noite), e no terceiro dia a VNI era utilizada apenas em período nocturno.

Resultados

Sessenta doentes iniciaram o protocolo de desmame. O tempo médio de VNI foi de 120.9 horas (17 a 192 horas). Não houve registo de complicações nos doentes que iniciaram este protocolo. Todos completaram o protocolo sem necessidade de reinstituir VNI ou ventilação invasiva durante o internamento.

Conclusões

Descrevemos uma taxa excelente de sucesso de desmame de VNI em doentes com exacerbações agudas de doentes com insuficiência respiratória crónica. Apesar de este protocolo implicar uma duração de 72 horas, os resultados sugerem que estratégias baseadas em períodos com e sem VNI são eficazes. No entanto, estratégias menos demoradas merecem investigação.

Palavras-chave:
Ventilação não invasiva
insuficiência respiratória crónica
desmame
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