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Vol. 11. Issue 5.
Pages 477-485 (September - October 2005)
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Vol. 11. Issue 5.
Pages 477-485 (September - October 2005)
Artigo de Revisão\Revision Article
Open Access
Alterações pleurais e parenquimatosas relacionadas com a exposição ao asbesto: Ensaio pictórico
Asbestos-related pleuropulmonary diseases: Pictorial essay
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G.S.P. Meirelles1,
Corresponding author
gustavo.meirelles@fleury.com.br

Instituição / Departamento: Grupo Interinstitucional para Estudo das Doenças Relacionadas ao Asbesto. UNIFESP/EPM, INCOR/ HCFMUSP e UNICAMP. Brasil. Endereço para correspondência: Dr. Dany Jasinowodolinski – Rua Doutor Diogo de Faria, 1077 / 102 – Vila Clementino – 04037-003 – São Paulo –SP, Brasil.
, J.I. Kavakama2, D. Jasinowodolinski3, L.E. Nery4, M. Terra-Filho5, R.T. Rodrigues6, J.A. Neder7, E. Bagatin8, G. D’ippolito9
1 Doutor em Radiologia pela Universidade Federal de São Paulo – Escola Paulista de Medicina (UNIFESP/EPM). São Paulo – SP, Brasil.
2 Médico assistente da Coordenação de Imagem do Instituto do Coração (INCOR) e supervisor do Grupo de Tórax do Instituto de Radiologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (INRAD HC-FMUSP). São Paulo – SP, Brasil.
3 Médico do Sector de Radiologia Torácica do Centro de Medicina Diagnóstica Fleury. São Paulo - SP, Brasil.
4 Professor adjunto da Disciplina de Pneumologia da Universidade Federal de São Paulo – Escola Paulista de Medicina (UNIFESP/EPM). São Paulo – SP, Brasil.
5 Professor associado da Disciplina de Pneumologia do INCOR do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP). São Paulo – SP, Brasil.
6 Professor do Departamento de Diagnóstico por Imagem da Universidade Federal de São Paulo – Escola Paulista de Medicina (UNIFESP/EPM). São Paulo – SP, Brasil.
7 Professor Doutor do Sector de Função Pulmonar e Fisiologia Clínica do Exercício (SEFICE) da Disciplina de Pneumologia da Universidade Federal de São Paulo – Escola Paulista de Medicina (UNIFESP/EPM). São Paulo – SP, Brasil.
8 Professor assistente da Área de Saúde Ocupacional – Departamento de Medicina Preventiva e Social da Faculdade de Ciências Médicas da Universidade Estadual de Campinas (UNICAMP). Professor adjunto da Disciplina de Pneumologia da Faculdade de Medicina de Jundiaí – SP, Brasil.
9 Professor visitante do Departamento de Diagnóstico por Imagem da Universidade Federal de São Paulo – Escola Paulista de Medicina (UNIFESP/EPM). São Paulo – SP, Brasil.
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Resumo

As alterações pleurais e pulmonares decorrentes da exposição ao asbesto podem ser benignas, como o derrame e as placas pleurais, ou malignas, como o carcinoma de pulmão e o mesotelioma pleural. O derrame pleural é a manifestação mais comum nos primeiros anos após a exposição e os aspectos de imagem são incaracterísticos. O espessamento pleural difuso compromete a pleura visceral, não sendo específico da exposição ao asbesto. As placas pleurais, espessamentos focais da pleura, são consideradas marcadores de exposição. A asbestose corresponde à fibrose do parênquima pulmonar pelo asbesto, predominando nos lobos inferiores, e a atelectasia redonda a um colapso pulmonar periférico, geralmente associado a alterações pleurais. O carcinoma pulmonar e o mesotelioma pleural são mais prevalentes em indivíduos expostos. O objectivo deste estudo é ilustrar as principais alterações de imagem das alterações relacionadas com o asbesto.

Rev Port Pneumol 2005; XI (5): 477-485

Palavras-chave:
Asbesto
pneumoconioses
doenças ocupacionais
Abstract

Pleural and pulmonary asbestos-related diseases range from benign conditions, like pleural effusion and pleural plaques, to some neoplasias, such as lung cancer and malignant mesothelioma. Pleural effusion is the earliest finding after asbestos exposure, but the imaging findings are not specific. Diffuse pleural thickening involves the visceral pleura and pleural plaques are considered to be hallmarks of exposure. Asbestosis is the pulmonary fibrosis due to asbestos. Rounded atelectasis is a peripheral lung collapse in these individuals, generally related to pleural disease. Some neoplasias, like lung carcinoma and pleural mesothelioma, are more prevalent in asbestos-exposed subjects. The aim of this essay is to illustrate the main imaging findings of asbestos-related diseases.

Rev Port Pneumol 2005; XI (5): 477-485

Key-words:
Asbestos
pneumoconioses
occupational diseases
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Bibliografia
[1.]
D.R. Aberle, J.R. Balmes.
Computed tomography of asbestos-related pulmonary parenchymal and pleural diseases.
Clin Chest Med, 12 (1991), pp. 115-131
[2.]
W.R. Webb, N.L. Müller, D.P. Naidich.
Asbestosis and asbestos-related disease.
High-resolution CT of the lung, 3rd ed, pp. 236-257
[3.]
K.I. Kim, C.W. Kim, M.K. Lee, K.S. Lee, C.K. Park, S.J. Choi, et al.
Imaging of occupational lung disease.
Radiographics, 21 (2001), pp. 1371-1391
[4.]
C.A. Staples.
Computed tomography in the evaluation of benign asbestos-related disorders.
Radiol Clin North Am, 30 (1992), pp. 1191-1207
[5.]
G.R. Epler, T.C. McLoud, E.A. Gaensler.
Prevalence and incidence of benign asbestos pleural effusion in a working population.
JAMA, 247 (1982), pp. 617-622
[6.]
G. Hillerdal, M. Ozesmi.
Benign asbestos pleural effusion: 73 exudates in 60 patients.
Eur J Respir Dis, 71 (1987), pp. 113-121
[7.]
K. Wernecke.
Ultrasound study of the pleura.
Eur Radiol, 10 (2000), pp. 1515-1523
[8.]
P.A. Gevenois, S. Trogrlic.
Imaging of the pleura.
Rev Prat, 47 (1997), pp. 1304-1307
[9.]
A. Solomon.
Radiological features of asbestos-related visceral pleural changes.
Am J Ind Med, 19 (1991), pp. 339-355
[10.]
D.A. Lynch, G. Gamsu, D.R. Aberle.
Conventional and high resolution computed tomography in the diagnosis of asbestos-related diseases.
Radiographics, 9 (1989), pp. 523-551
[11.]
R.N. Jones.
Pleural plaques: diagnostic problems and significance.
Indoor Built Environ, 6 (1997), pp. 106-113
[12.]
G. Hillerdal.
Nonmalignant pleural disease related to asbestos exposure.
Clin Chest Med, 6 (1985), pp. 141-152
[13.]
B. Christen, W. Wegmann, P. Vogt.
Clinical pathology and histology of pleural plaques.
Indoor Built Environ, 6 (1997), pp. 79-85
[14.]
C. Peacock, S.J. Copley, D.M. Hansell.
Asbestos-related benign pleural disease.
Clin Radiol, 55 (2000), pp. 422-432
[15.]
H.D. Roach, G.J. Davies, R. Attanoos, M. Crane, H. Adams, S. Phillips.
Asbestos: when the dust settles an imaging review of asbestos-related disease.
[16.]
M.R. Becklake.
Asbestos-related diseases of the lung and other organs: their epidemiology and implications for clinical practice.
Am Rev Respir Dis, 114 (1976), pp. 187-227
[17.]
G. Gamsu, C.J. Salmon, M.L. Warnock, P.D. Blanc.
CT quantification of interstitial fibrosis in patients with asbestosis: a comparison of two methods.
AJR Am J Roentgenol, 164 (1995), pp. 63-68
[18.]
T.C. McLoud.
Conventional radiography in the diagnosis of asbestos-related disease.
Radiol Clin North Am, 30 (1992), pp. 1177-1189
[19.]
D.R. Aberle, G. Gamsu, C.S. Ray, I.M. Feuerstein.
Asbestos-related pleural and parenchymal fibrosis: detection with high- resolution CT.
Radiology, 166 (1988), pp. 729-734
[20.]
A.C. Friedman, S.B. Fiel, M.S. Fisher, P.D. Radecki, A.S. Lev-Toaff, D.F. Caroline.
Asbestos-related pleural disease and asbestosis: a comparison of CT and chest radiography.
AJR Am J Roentgenol, 150 (1988), pp. 269-275
[21.]
G. Hillerdal.
Rounded atelectasis. Clinical experience with 74 patients.
Chest, 95 (1989), pp. 836-841
[22.]
K. McHugh, R.M. Blaquiere.
CT features of rounded atelectasis.
AJR Am J Roentgenol, 153 (1989), pp. 257-260
[23.]
G. Hillerdal.
The pathogenesis of pleural plaques and pulmonary asbestosis: possibilities and impossibilities.
Eur J Respir Dis, 61 (1980), pp. 129-138
[24.]
R. Bégin, J.M. Samet, R.A. Shaikh.
Asbestos.
Occupational and environmental respiratory disease, pp. 293-321
[25.]
M. Akira, K. Yokoyama, S. Yamamoto, T. Higashihara, K. Morinaga, N. Kita, et al.
Early asbestosis: evaluation with high-resolution CT.
Radiology, 178 (1991), pp. 409-416
[26.]
American Thoracic Society.
Medical Section of the American Lung Association: The diagnosis of nonmalignant diseases related to asbestos.
Am Rev Respir Dis, 134 (1986), pp. 363-368
[27.]
M. Akira, S. Yamamoto, Y. Inoue, M. Sakatani.
High-resolution CT of asbestosis and idiopathic pulmonary fibrosis.
AJR Am J Roentgenol, 181 (2003), pp. 163-169
[28.]
R.A. Lemen, J.M. Dement, J.K. Wagoner.
Epidemiology of asbestos-related diseases.
Environ Health Perspect, 34 (1980), pp. 1-11
[29.]
K. Garg, D.A. Lynch.
Imaging of thoracic occupational and environmental malignancies.
J Thorac Imaging, 17 (2002), pp. 198-210
[30.]
V.I. Adams, K.K. Unni, J.R. Muhm, J.R. Jett, D.M. Ilstrup, P.E. Bernatz.
Diffuse malignant mesothelioma of pleura. Diagnosis and survival in 92 cases.
Cancer, 58 (1986), pp. 1540-1551
[31.]
E.B. Gottschall.
Occupational and environmental thoracic malignancies.
J Thorac Imaging, 17 (2002), pp. 189-197
[32.]
N.L. Muller.
Imaging of the pleura.
Radiology, 186 (1993), pp. 297-309
[33.]
S.L. Nishimura, V.C. Broaddus.
Asbestos-induced pleural disease.
Clin Chest Med, 19 (1998), pp. 311-329
[34.]
T.C. McLoud.
CT and MR in pleural disease.
Clin Chest Med, 19 (1998), pp. 261-276
[35.]
E.M. Marom, J.J. Erasmus, H.I. Pass, E.F. Patz Jr..
The role of imaging in malignant pleural mesothelioma.
Semin Oncol, 29 (2002), pp. 26-35
[36.]
R.T. Heelan, V.W. Rusch, C.B. Begg, D.M. Panicek, J.F. Caravelli, C. Eisen.
Staging of malignant pleural mesothelioma: comparison of CT and MR imaging.
AJR Am J Roentgenol, 172 (1999), pp. 1039-1047
[37.]
F. Benard, D. Sterman, R.J. Smith, L.R. Kaiser, S.M. Albelda, A. Alavi.
Prognostic value of FDG PET imaging in malignant pleural mesothelioma.
J Nucl Med, 40 (1999), pp. 1241-1245
[38.]
J. Zubeldia, M. Abou-Zied, H. Nabi.
Evaluation of Patients with Known Mesothelioma with 18F-Fluorodeoxyglucose and PET. Comparison with Computed Tomography.
Clin Positron Imaging, 3 (2000), pp. 165
Copyright © 2005. Sociedade Portuguesa de Pneumologia/SPP
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