Article information
RESUMO
A Criptococose é uma infecção relativamente rara causada por um fungo, o Cripwcoccus neofornrans, que se encontra largamente distribuido por todo o mundo. Após a sua inalação as manifestações clínicas variam desde uma simples colonização pulmonar até uma infecção disseminada e invasiva. A maioria dos casos ocorre em doentes imunodeprimidos sendo a meningoencefalite a principal mani-festação da criptococose.
Os autores apresentam um caso de criptococose pulmonar num doente jovem e imunocompetente.
REV PORT PNEUMOL 1999; V (4): 419-426
Palavras-chave:
Criptococose
micose pulmonar
punção aspirativa transtorácica
ABSTRACT
Cryptococcosis is a relatively rare infection, caused by the yeast-like fungus Cryptococcus neoformans, an organism with a worldwide distribution. After the inhalation of Cryptococcus neoformans the clinical manifestations range from Pulmonary colonization to disseminated invasive fungal infection. Most cases occur in immunocompromised patients and meningoencephalitis is the most common manifestation of cryptococcosis.
We describe one case of pulmonary cryptococcosis in an immunocompetent young male patient.
REV PORT PNEUMOL 1999; V (4): 419-426
Key-words:
Criptococosis
pulmonary mycosis
percutaneous fine needle aspiration
Full text is only aviable in PDF
REFERENCES
[1.]
Larone DH. Medically Important Fungi A Guide to Identification. 3rd ed. American Society of Microbiology. Washington DC.
[2.]
M.L. Cameron, J.R. Perfect.
Pulmonary cryptococcosis pathophysiological and clinical characteristics.
Pulmonary infectious and Immunity, pp. 249
[3.]
Koneman et at. Color Atlas and Textbook of Diagnostic Microbiology. 4th Edition. JB Lippincott Company, Philadelphia.
[4.]
M.C. Boyars, J.B. Zwischenberger, C.S. Cox.
Clinical manifestations of pulmonary fungal infection.
J Thoracic Imaging, 7 (1992), pp. 12-22
[5.]
G.S. Deepe, W.E. Bullock.
Immunological aspects of fungal pathogenesis.
European Journal of Clinical Microbiology and Infectious Disease, 9 (1990), pp. 377-380
[6.]
R. Duperval, P.E. Hermans, N.S. Brewer, et al.
Cryptococcosis, with emphasis on the significance of isolation of Cryptococcuse neoformans from respiratory tract.
Chest, 72 (1977), pp. 13-19
[7.]
T.M. Kerkering, R.J. Durma, S. Shadomy.
The evolution of pulmonary cryptococcosis.
Ann Intern Med, 94 (1981), pp. 611-616
[8.]
Dail D, Hammar S Pulmonary Pathology 2nd Edition Springer – Verlag, New York.
[9.]
K.J. Kwon-Chung.
Cryptococcosis.
Medical mycology, pp. 397-446
[10.]
Murray et al. Manual of Clinical Microbiology. 6th edition. American Society of Microbiology Press. Washington-DC.
[11.]
W.E. Dismukes.
Cryptococcal meningitis in patients with AIDS.
J Infec Dis, 157 (1988), pp. 624-628
[12.]
L.M. Mundy, W.G. Powderly.
Invasive fungal infections.
Cryptococcosis Semin Resp Care Med, 18 (1997), pp. 249-257
[13.]
M. Goldman, L.J. Wheat.
Cryptococcal infections.
Fishman’s Pulmonary Diseases and Disorders, 3, McGraw-Hill Companies, inc, (1998), pp. 2305-2312
[14.]
K.J. Kwon-Chung.
Cryptococcosis.
pp. 397-446
[15.]
T.G. Mitchell, J.R. Perfect.
Cryptococcosis in the era of AIDS – 100 years after the discover of C. neoformans.
Cli Microbiol Rev, 8 (1995), pp. 515-548
[16.]
G.B. Huffnagle, J.L. Yates, M.F. Lipscomb.
Immunity to a pulmonary Cryptococcus neoformans infection requires both CD4+ and CD8+ T cells.
J Exp Med, 173 (1991), pp. 793-800
[17.]
R.D. Diamond.
Principles and Practice of Infectious Diseases.
4, pp. 2232-2340
[18.]
F. Dromer, S. Mathoulin, B. Dupont, A. Laporte, French Ryptococcosis Study Group.
Epidemiology of cryptococcosis in France A 9-year survey (1985-1993).
Clin Infect Dis, 23 (1996), pp. 82-90
[19.]
S.M. Levitz.
The ecology of C. neoformans and the epidemiology of cryptococcosts.
Rev Infect Dis, 13 (1991), pp. 1163-1169
[20.]
D.H. Ellis, T.J. Pfeiffer.
Ecology, life cycle. and infectious propagate of Cryptococcus neoformans.
Lancet, 336 (1990), pp. 923-925
[21.]
G.O. Campbell.
Primary pulmonary cryptococcosis.
Am Rev Respir Dis, 94 (1966), pp. 236-243
[22.]
R. Rozenbaum, A.J.R. Gonçalves.
Clinical epidemiology study of 171 cases of cryptococcosis.
Clin Infect Dis, 18 (1994), pp. 369-380
[23.]
M.C. Meyohas, P. Roux, D. Bollens, et al.
Pulmonary cryptococcosis Localized and disseminated infectjons in 27 pauents with AIDS.
Clin Infect Dis, 21 (1995), pp. 628-633
[24.]
E.P. Friedman, R.F. Miller, A. Severn, et al.
Cryptococcal pneumonia in patients with acquired immunodeficiency syndrome.
Clin Radiol, 50 (1995), pp. 756-760
[25.]
E.N. Perla, S. Maayan, S.N. Miller, et al.
Disseminated cryptococcosis presenting as the adult respiratory distress syndrome.
Y State J Med, 85 (1985), pp. 704-706
[26.]
V.E. Mulanovich, W.E. Dismukes, N. Markowitz.
Cryptococcal empyema case report and review.
Clin Infect Dis, 20 (1995), pp. 1396-1398
[27.]
D.J. Signs, D.S. Wagner.
Pulmonary Cryptococcus presenting as Pneumothorax in a pattent with AIDS.
Clin Infect Dis, 21 (1995), pp. 1524-1525
[28.]
D.H. Mitchell, T.C. Sorrell.
Pancoast’s syndrome due to pulmonary Infection with Cryptococcus neoformans variety gattii.
Clin Infect Dis, 14 (1992), pp. 1142-1144
[29.]
Douketjs JD, Keste S Miliary pulmonary cryptococcosis tn a patient with the acquired immunodeficiency syndrome. Thorax, 48: 402–3.
[30.]
M. Goldman, L.J. Wheat.
Cryptococcal infections.
Fishman’s Pulmonary Diseases and Disorders, 3, McGraw-Hill Companies, Inc, (1998), pp. 2305-2312
[31.]
A.E. Watis.
Localized pulmonary cryptococcosis: diagnosis by fine needle aspiration.
Acta Cyto, 27 (1983), pp. 457-459
[32.]
J.F. Silyerman, I.S. Johnrude.
Fine needle aspirauon cytology of granulomatous cryptococcosis of the lung.
Acta Cyto, 29 (1985), pp. 157-161
[33.]
K.J. Kwon-Chung, J.E. Bennet.
Medical Mycology, Lea & Febiger, (1992),
[34.]
Y.S. Liaw, P.C. Yang, C.J. Yu, D.B. Chang, H.J. Wang, L.N. Lee, S.H. Kuo, K.T. Luh.
Direct determinauon of cryptococcal antigen in transthoractc needle aspirate for diagnosis of pulmonary cryptococcosis.
J Clin Microbicl, 33 (1995), pp. 1588-1591
[35.]
R.P. Baughman, J.C. Rhodes, M.N. Dohn, H. Henderson, P.T. Frame.
Detection of cryptococcal antigen in bronchoalveolar lavage fluid: a prospective study diagnostic utility.
Am Rev Respir Dis, 145 (1992), pp. 1226-1229
[36.]
E.J. Young, D.D. Hirsh, V. Fajnstein, T.W. Williams.
Pleural effusions due to Cryptococcus neoformans a review of the literature and report of two cases with cryptococcal antigen determinations.
Am Rev Respir Dis, 121 (1980), pp. 743-747
[37.]
W.A. Jensen, R.M. Rose, S.M. Hammer, A.W. Karchmer.
Serologic diagnosis of focal pneumonia caused by Cryprotococcus neoformans.
Am Rev Respir Dis, 132 (1985), pp. 189-191
[38.]
J.A. Aberg, L.M. Mundy, W.G. Powderly.
Pulmonary cryptococcosis in Patients without HIV Infection.
Chest, 115 (1999), pp. 734-740
[39.]
E.F. Patz, P.C. Goodman.
Pulmonary cryptococcosis.
J Thoracic Imaging, 7 (1992), pp. 51-55
[40.]
T.M. Kerkering, R.J. Duma, S. Shadomy.
The evolution of pulmonary cryptococcosis clinical implications from a study of 41 patients with and without compromising host factors.
Annals of Internal Medicine, 94 (1981), pp. 611-616
Copyright © 1999. Sociedade Portuguesa de Pneumologia/SPP
Open access
This work is licensed under a Creative Commons Attribution 4.0 International License.
Publish in
Pulmonology
Pulmonology
- Home
- All contents
- Publish your article
- About the journal
- Metrics
- Open access
Article options