Diferenciais celulares e subpopulações linfocitárias no LBA da pneumonia de hipersensibilidade

Costabel, Ulrich

doi:10.1016/S0873-2159(15)30885-0

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RESUMO

Fazse uma profunda revisão das características do Lavado Broncoalveolar nas Pneumonias de Hipersensibilidade (PH). Discute-se o perfil do LBA nas diferentes fases de PH, da relação T4/T8 e dos marcadores de actividades dos linfocitos. Seguidamente são apresentados os resultados do LBA em indivíduos expostos assintomáticos e os padrões de alveolite que aparecem no follow-up destes doentes. Finalmente defendese a relevância diagnóstica de LBA na Pneumonia de Hipersensibilidade.

REV PORT PNEUMOL 2000; VI (3): 187-193

Palavras-chave:

LBA

subpopulações linfocitárias

pneumonia de hipersensiblidade

ABSTRACT

A thorough review on BAL data in hipersensitivity pneumonitis (HP) is made. The HAL cell profile on the different phases of HP is discussed, the CD4/CD8 ratio, the lung Tcell murkers of activation. Then the BAL findings in asymptomatic exposed Individual are addressed as the pattern of alveolitis during follow-up. Finally the diugnostic relevance of the BAL findings in HP is defended.

REV PORT PNEUMOL 2000; VI (3): 187-193

Key-words:

BAL

Limphocyte subsets

Hypersensitivity pneumonitis

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