Journal Information
Vol. 12. Issue 5.
Pages 563-579 (September - October 2006)
Share
Share
Download PDF
More article options
Vol. 12. Issue 5.
Pages 563-579 (September - October 2006)
Artigo de Revisão / Revision Article
Open Access
Doenças inflamatórias alérgicas das vias aéreas superiores e suas implicações na asma brônquica – A propósito de um caso clínico
Allergic inflammatory diseases of the upper airways and their impact on asthma – Following on from a case report
Visits
5601
Ana L. Fonseca1, Ana M. Arrobas2
1 Interna do Complementar de Pneumologia, Serviço de Pneumologia
2 Assistente Hospitalar Graduada de Pneumologia, Hospital Geral do Centro Hospitalar de Coimbra, Quinta dos Vales, Coimbra
This item has received

Under a Creative Commons license
Article information
Resumo

Os autores apresentam o caso clínico de uma doente referenciada à consulta de alergologia respiratória por “asma de difícil controlo”. A investigação clínica conduziu à identificação de patologia inflamatória crónica das vias aéreas superiores de carácter grave, como factor de agravamento da asma brônquica. Após terapêutica, que no referido caso implicou abordagem cirúrgica dos seios perinasais, houve melhoria franca do controlo da asma. A propósito do caso, é efectuada uma revisão das principais patologias inflamatórias alérgicas das vias aéreas superiores (rinite, sinusite e polipose nasal) e abordadas as suas principais implicações no controlo da asma brônquica.

Rev Port Pneumol 2006; XII (5): 563-580

Palavras-chave:
Asma brônquica
rinite alérgica
sinusite crónica
polipose nasal
Abstract

The authors present a case report of a patient refered to physician for “difficult-to-treat asthma”. Clinical evaluation concluded that severe chronic inflammatory upper airway disease was an asthma worsening factor. Patient demonstrated improvement in asthma control, after surgery.

In the context of the clinical study, the authors present a review of the most common allergic inflammatory diseases of the upper airways (allergic rhinitis, chronic sinusitis and nasal polyposis) and reflect on their impact on asthma.

Rev Port Pneumol 2006; XII (5): 563-580

Key-words:
Asthma
allergic rhinitis
chronic sinusitis
nasal polyposis
Full text is only aviable in PDF
Bibliografia
[1.]
E. Nutku, M. Toda, Q.A. Hamid.
Rhinitis, nasal polyposis and asthma: pathological aspects.
The Nose and Lung Diseases. European Respiratory Monograph. Vol. 6. Monograph 18, 9 (2001), pp. 115-132
[2.]
Global Strategy for Asthma Management and Prevention, National Institutes of Health. National Heart, Lung and Blood Institute, (2005),
[3.]
J. Bousquet, P. Van Cauwenberge, N. Khaltaev.
Allergic Rhinitis and its Impact on Asthma (ARIA).
J Allergy Clin Immunol, 108 (2001), pp. 5174-5334
[4.]
C. Serrano, A. Valero, C. Picado.
Rhinitis and Asthma: One Airway.
One Disease. Arch Bronconeumol, 41 (2005), pp. 569-578
[5.]
Bénédicte Leynaert, Jean Bousquet, Catherine Neukirch, Renata Liard, Françoise Neukirch.
Perennial Rhinitis: An independent risk factor for asthma in nonatopic subjects.
J Allergy Clin Immunol, 104 (1999), pp. 301-304
[6.]
J. Corren, A. Adinoff, C. Irvin.
Changes in bronchial responsiveness following nasal provocation allergen.
J Allergy Clin Immunol, 89 (1992), pp. 611-618
[7.]
M. Schumaker, K. Cora, L. Taussig.
Pulmonary response to nasal-challenge testing of athopic subject with stable asthma.
J Allergy Clin Immunol, 78 (1986), pp. 30-35
[8.]
N. Littell, C. Carlisle, R. Millman, S. Braman.
Changes in airway resistance following nasal provocation.
Am Rev Resp Dis, 141 (1990), pp. 580-583
[9.]
A. Togias.
Systemic immunologic and inflammatory aspects of allergic rhinitis.
J Allergy Clin Immunol, 106 (2000), pp. S247-S250
[10.]
C. McCusker, M. Chicoine, D. Hamid, B. Mazer.
Site-specific sensitisation in a murine model of allergic rhinitis: role of the upper airway in lower airway disease.
J. Allergy Clin Immunol, 110 (2002), pp. 891-898
[11.]
G.J. Braunstahl, S.E. Overbeek, A. KleinJan, J.B. Prins, H.C. Hoogsteden, W.J. Fokkens.
Nasal allergen provocation induces adhesion molecule expression and tissue eo-sinophilia in upper and lower airways.
J Allergy Clin Immunol, 107 (2001), pp. 469-476
[12.]
K.M. Beeh, J. Beier, O. Kornmann, C. Meier, T. Taeumer, R. Buhl.
A single nasal allergen challenge increases induced sputum inflammatory markers in non-asthmatic subjects with seasonal allergic rhinitis: correlation with plasma interleukin-5.
Clin Exp Allergy, 33 (2003), pp. 475-482
[13.]
G.J. Braunstahl, A. KleinJan, S.E. Overbeek, J.B. Prins, H.C. Hoogsteden, W.J. Fokkens.
Segmental bron- chial provocation induces nasal inflammation in allergic rhinitis patients.
Am J Resp Crit Care Med, 161 (2000), pp. 2051-2057
[14.]
G.J. Braunstahl, S.E. Overbeek, W.J. Fokkens, A. KleinJan, A.R. McEuen, A.F. Walls, et al.
Segmental bronchopro-vocation in allergic rhinitis affects mast cell and basophil numbers in nasal and bronchial mucosa.
Am J Resp Crit Care Med, 161 (2001), pp. 858-865
[15.]
Giovanni Passalacqua, Giorgio Ciprandi, Mercedes Pasquali, Laura Guerra, Giogio Canonica.
An update on the asthma – rhinitis link.
Curr Opin Allergy Clin Immunol, 4 (2004), pp. 177-183
[16.]
Durham SR, Mackay S. Diseases of the nose. In Respiratory Medicine. Volume 2. Third Edition. 43:1035-47. Gibson GJ, Geddes DM, Costabel U, Sterk PJ, Corrin B, editors. Saunders.
[17.]
John Weiner, Michael Abramson, Robert Puy.
Intra-nasal corticosteroids versus oral H1 receptor antagonists in allergic rhinitis: systematic review of randomised con-trolled trials.
BMJ, 317 (1998), pp. 1624-1629
[18.]
George Philip, Anjuli S. Nayak, William Berger, Francisque Leynadier, France Vrijens, S. Balachandra Dass, Theodore Reiss.
The effect of montelukast on rhinitis symptoms in patients with asthma and seasonal allergic rhinitis.
Curr Med Res, 20 (2004), pp. 1549-1558
[19.]
Stephan Durham, Stephan J. Till.
Immunologic changes associated with allergen imunotherapy.
J Allergy Clin Immunol, 102 (1998), pp. 157-164
[20.]
Samantha M. Mucha, Fuad M. Baroody. Sinusitis Update. Curr Opin Allergy Clin Immunol 3:33-38.
[21.]
Donald C. Lanza, David W. Kennedy.
Adult rhinosi-nusitis defined.
Otoryngol Head Neck Surg, 117 (1997), pp. S1-S7
[22.]
Carlos Lucas. Asma de difícil controlo. In Tratado de Pneumologia. Vol. I. 66.5: 909-920. Gomes MJ, Sotto-Mayor R (eds.). Sociedade Portuguesa de Pneumologia.
[23.]
M. Bresiani, L. Paradis, A. Des Roches, et al.
Rhinosi-nusitis in severe asthma.
J Allergy Clin Immunol, 107 (2001), pp. 73-80
[24.]
A. Tosca, A.M. Riccio, G.L. Marseglia, et al.
Nasal en-doscopy in asthmatic children: assessment of rhinosinusitis and adenoiditis incidence, correlations with cytology and microbiology.
Clin Exp Allergy, 31 (2001), pp. 609-615
[25.]
A.T. Brinke, D.C. Grootendorst, J.T. Schmidt, et al.
Chronic sinusitis in severe asthma is related to sputum eosi-nophilia.
J Allergy Clin Immunol, 109 (2002), pp. 621-626
[26.]
J. Mensa, J.M. Gatell, J.R. Azanza, A. Dominguez-Gil, J.E. Garcia, Jiminez de Anta MT, G. Prats.
Guía de Terapêutica Antimicrobiana.
Masson, 3 (2005), pp. 407-410
[27.]
Cori Copilevitz, Raymond Slavin.
Sinusitis and asthma.
pp. 61-65
[28.]
F. Lavigne, L. Cameron, P.M. Renzi, et al.
Intrasinus administration of topical budesonide to allergic patients with chronic sinusitis following surgery.
Laryngoscope, 112 (2002), pp. 858-864
[29.]
J.M. Rowe-Jones.
The link between the nose and lung, perennial rhinitis and asthma-is it the same disease?.
Allergy, 52 (1997), pp. 20-28
[30.]
H.-J. Dhong, Y.S. Jung, S.K. Chung, D.C. Choi.
Effect of endoscopic sinus surgery on asthmatic patients with chronic rhinosinusitis.
Otolaryngol Head Neck Surg, 124 (2001), pp. 99-104
[31.]
J.N. Palmer, D.B. Conley, R.G. Dong, A.M. Ditto, P.R. Ya-mold, R.C. Kern.
Efficacy of endoscopic surgery in the management of patients with asthma and chronic sinusitis.
Am J Rhinol, 15 (2001), pp. 49-53
[32.]
G. Dunlop, G.K. Scadding, V.J. Lund.
The effect of endoscopic sinus surgery asthma: management of patients with chronic rhinosinusitis, nasal polyposis, and asthma.
Am J Rhinol, 13 (1999), pp. 261-265
[33.]
Ruby Pawanker.
Nasal polyposis: an update.
Cur Opin Allergy Clin Immunol, 3 (2003), pp. 1-6
[34.]
R. Pawliczak, A. Lewandowska-Polak, M.L. Kowalski.
Pathogenesis of nasal polyps: an update.
Curr Allergy Asthma Rep, 5 (2005 Nov), pp. 463-471
[35.]
C. Bachert, T. Van Zele, P. Gevaert, L. De Schrijver, P. Van Cauwenberge.
Superantigens and nasal polyps.
Curr Allergy Asthma Rep, 3 (2003), pp. 523-531
[36.]
Drake-Lee.
Nasal polyps.
Hosp Med, 65 (2004), pp. 264-267
[37.]
R. Wynn, G. Har-El.
Recorrence rates after endoscopic sinus surgery for massive sinus polyposis.
Laryngoscope, 114 (2004), pp. 811-813
[38.]
G.M. English.
Nasal polypectomy and sinus surgery in patients with asthma and aspirin idiosyncrasy.
Laryngoscope, 96 (1986), pp. 374-380
Copyright © 2006. Sociedade Portuguesa de Pneumologia/SPP
Download PDF
Pulmonology
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?