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Journal Information
Vol. 14. Issue 3.
Pages 421-425 (May - June 2008)
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Vol. 14. Issue 3.
Pages 421-425 (May - June 2008)
Caso Clínico/Clinical Case
Open Access
Hemangioendotelioma epitelióide – Um tumor pulmonar raro
Epithelioid hemangioendothelioma – A rare pulmonary tumor
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Sandra Saleiro1,
Corresponding author
sandrasaleiro@portugalmail.pt

Correspondência: Sandra Saleiro, Serviço de Pneumologia - Hospital de São João, Alameda Prof. Hernâni Monteiro, 4202-451 – Porto – Portugal
, Miguel Barbosa2, Conceição Souto Moura3, João Almeida4, Silva Ferreira5
1 Interna Complementar de Pneumologia, Serviço de Pneumologia, Hospital de São João, Faculdade de Medicina da Universidade do Porto – Porto
2 Interno Complementar de Oncologia Médica, Serviço de Oncologia Médica, Hospital de São João, Faculdade de Medicina da Universidade do Porto – Porto
3 Assistente Hospitalar de Anatomia Patológica, Serviço de Anatomia Patológica, Hospital de São João, Faculdade de Medicina da Universidade do Porto – Porto
4 Chefe de Serviço de Pneumologia, Serviço de Pneumologia, Hospital de São João, Faculdade de Medicina da Universidade do Porto – Porto
5 Chefe de Serviço de Medicina Interna, Hospital de São João, Faculdade de Medicina da Universidade do Porto – Porto
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Resumo

Os autores descrevem um caso de uma neoplasia pulmonar rara – hemangioendotelioma epitelióide – numa doente do sexo feminino, de 39 anos, assintomática até Dezembro de 2003, altura em que apresentou toracalgia direita de características pleuríticas. A doente era portadora de uma radiografia torácica antiga, efectuada há 13 anos, que revelava múltiplos pequenos nódulos pulmonares bilaterais, atribuídos a sequelas de tuberculose pulmonar. O diagnóstico histológico definitivo foi efectuado através de biópsia pulmonar por toracotomia. Dado a doente ter apresentado agravamento clínico e imagiológico foi iniciada terapêutica com interferão α-2a. Apesar da estabilidade imagiológica das lesões pulmonares, a doente manteve-se sintomática e faleceu nove meses depois do diagnóstico ter sido estabelecido.

Os autores realçam a raridade deste tipo de neoplasia pulmonar e discutem a sua apresentação clínica, características histológicas, tratamento e prognóstico.

Rev Port Pneumol 2008; XIV (3): 421-425

Palavras-chave:
Hemangioendotelioma epitelióide
pulmão
interferão α
Abstract

The authors report a case of a rare pulmonary neoplasm – epithelioid hemangioendothelioma, in a 39 year-old woman, asymptomatic until December 2003, when she developed pleuritic and right-sided chest pain. The patient presented a previous chest radiograph, performed 13 years before, which showed multiple small bilateral pulmonary nodules attributed to tuberculous sequelae. The definitive histological diagnosis was made by lung biopsy through thoracotomy. The patient developed a clinical and imagiological worsening and then therapy with interferon α-2a was started. Even with imagiological stability of pulmonary lesions the patient remained symptomatic and died nine months after the diagnosis had been established.

The authors emphasise the rarity of this type of pulmonary neoplasm and discuss its clinical presentation, histological features, treatment and prognosis.

Rev Port Pneumol 2008; XIV (3): 421-425

Key-words:
Epithelioid hemangioendothelioma
lung
interferon α
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Copyright © 2008. Sociedade Portuguesa de Pneumologia/SPP
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