Journal Information
Vol. 8. Issue 6.
Pages 681-688 (November - December 2002)
Share
Share
Download PDF
More article options
Vol. 8. Issue 6.
Pages 681-688 (November - December 2002)
ARTIGO DE REVISÃO/REVISION ARTICLE
Open Access
Pneumonia eosinofílica aguda Revisão clinica
Acute eosinophilic pneumonia Clinical review
Visits
5817
Maria Augusta Machado*, Adelina Amorim*, João Carlos Winck**
* Interna Complementar de Pneumologia, Serviço de Pneumologia do Hospital de São João - PortoDirector: Doutor Martins Coelho
** Assistente Hospitalar de Pneumologia, Serviço de Pneumologia do Hospital de São João - Porto Director: Doutor Martins Coelho
This item has received

Under a Creative Commons license
Article information
RESUMO

A pneumonia eosinofílica aguda (PEA) é uma doeça rara, de etiologia desconhecida, caracterizada por eosinofilia pulmonar marcada, geralmente não associada a aumento dos eosinófilos no sangue periférico. Apresentase como um quadro febril agudo, frequentemente grave, associado a infiltrados pulmonares. O lavado broncoalveolar é muito sugestivo do diagnostico, mas a sua confirmação definitiva baseiase no estudo histologico do tecido pulmonar. Tratase de uma doença sem expressão sistemica associada, que responde rapidamente à corticoterapia e que não apresenta recidivas.

REV PORT PNEUMOL 2002; VIII (6): 681-688

Palavras-chave:
Pneumonia eosinofílica
lavado broncoalveolar
corticosteróides
ABSTRACT

Acute eosinophilic pneumonia is a rare disease, of unknown etiology, characterized by lung eosinophilia without increase of eosinophils in the peripheral blood. It is an acute febrile illness, often severe, associated with pulmonary infiltrates. High percentage of eosinophils on broncoalveolar lavage is characteristic of the disease, but definitive confirmation is based on the histology of the lung. Corticosteroid therapy results in immediate improvement and doesn’t relapse.

REV PORT PNEUMOL 2002; VIII (6): 681-688

Key-words:
Eosinophilic pneumonia
bronchoalveolar lavage
conicosteroids
Full text is only aviable in PDF
BIBLIOGRAFIA
[1.]
D.B. Badesch, T.E. King, M.I. Schwarz.
Acute eosinophilic pneumonia: a hipersensitivity phenomenon?.
Am Rev Respir Dis, 139 (1989), pp. 249-252
[2.]
C.L. Rochester.
The eosinophilic pneumonias.
3rd edition, pp. 1133-1150
[3.]
A.L. Pope-Harman, W.B. Davis, E.D. Allen, A.J. Christoforidis, J.N. Allen.
Acute eosinophilic pneumonia: a summary of 15 cases and review of the literature.
Medicine, 75 (1996), pp. 334-342
[4.]
J.A. Boyce.
Eosinophilic lung syndromes.
[5.]
J.N. Allen, Pachter, J.E. Gadek, W.B. Davis.
Acute eosinophilic pneumonia as a reversible cause of noninfectious respiratory failure.
New Eng J Med, 321 (1989), pp. 569-574
[6.]
J. Mayo, J. Collazos, E. Martinez, F. Diaz.
Acute eosinophilic pneumonia Acute eosinophilic pneumonia in a patient infected with the HIY.
Tuber Lung Dis, 76 (1995), pp. 77-79
[7.]
D. Ricker, S. Taylor, J. Gartener, G. Kurland.
Fatal pulmonary Aspergillosis as a acute eosinophilic pneumonia in a previously healthy child.
Chest, 100 (1991), pp. 875-877
[8.]
D. Coetmeur, G. Guivarch, E. Briens, C. Lopes.
Acute eosinophilic pneumonia. possible role of chloroquine.
Rev Mal Respir, 15 (1998), pp. 657-660
[9.]
M.T. Barnes, J. Bascunana, B. Garcia, J.L. Alvarez­Sala.
Acute eosinophilic pneumonia associated with antidepressant agents.
Pharm World Sci, 21 (1999), pp. 241-242
[10.]
E. Miyazaki, K. Sugisaki, T. Shig Enaga, T. Matsu­Moto, S. Kita, Y. Ino Be, T. Tsuda.
A case of acute eosinophilic pneumonia caused by inhalation of Trichos­poron terrestre.
Am J Respir Crit Care Med, 151 (1995), pp. 541-543
[11.]
S. Imokawa, A. Sato, H. Hayakawa, M. Toyoshima, M. Tan Iguchi, K. Chida.
Possible involvement of an environmental agent in the development of acute eosinophilic pneumonia.
Ann Allergy Asthma Immunol, 76 (1996), pp. 419-422
[12.]
S. Imokawa, A. Sato, M. Taniguchi, M. Imamura, T. Shirai, T. Suda, M. Iwata, H. Gemma.
Two cases of acute eosinophilic pneumonia with precipitating antibody against Thricosporon cutaneum and Triclzoderma viride.
Nippon Kyobu Shikkan Gakkai Zasshi, 31 (1993), pp. 352-359
[13.]
K.J. Kelly, R. Ruffing.
Acute eosinophilic pneumonia following intentional inhalation of scotchguard.
Ann Allergy, 71 (1993), pp. 358-361
[14.]
R. Taki, M. Sawada, S. Isogai, S. Takano, A. Wata­ Nabe, S. Miyake, Y. Susuki, M. Tanone, S. Ohdama, T. Susuki, Y. Yoshizawa.
A possible role of cigarette smoking in the pathogenesis of acute eosinophilic pneumonia.
Am J Respir Crit Care Med, 153 (1996), pp. A271
[15.]
V. Godding, E. Bodart, M. Delos, Y. Sibille, L. Galanti, P. De Coster, N. Jarjour, W.W. Busse.
Mechanisms of acute eosinophilic infl ammation in a case of acute eosinophilic pneumonia in a 14-year-old girl.
Clin Exp Allergy, 28 (1998), pp. 504-509
[16.]
T. Maeno, Y. Maeno, Y. Sando, T. Takahashi, H. Yarita, M. Tsukagoshi, T. Suga, M. Kurabayashi, R. Nagai.
Nuclear hypersegmentation precedes the increase in blood eosinophils in acute eosinophilic pneumonia.
Intern Med, 39 (2000), pp. 157-159
[17.]
J.N. Allen, Z. Liao, M.D. Wewers, E.A. Altenberger, S.A. Moore, E.D. Allen.
Detection of IL-5 and IL-1 receptor antagonist in BAL in acute eosinophilic pneumonia.
J Allergy Clin Immunol, 97 (1996), pp. 1366-1374
[18.]
S. Yamaguchi, Y. Okubo, M. Hossain, K. Fujimoto, T. Honda, K. Kubu, M. Sekiguchi, K. Takatsu.
IL-5 predominant il BAL and periferal blood in a patient with acute eosinophilic pneumonia.
Intern Med, 34 (1995), pp. 65-68
[19.]
Y. Okubo, S. Horie, Y.A.T. Hachi, T. Momose, S. Tsukadaira, J. Susuki, M. Isobe, M. Sekiguchi.
Predominant implication of il-5 in acute eosinophilic pneumonia: comparison with chronic eosinophilic pneumonia.
Int Arch Allergy Immunol, 116 (1998), pp. 76-80
[20.]
Y. Okubo, M. Hossain, R. Kai, E. Sato, T. Honda, M. Sekiguchi, S. Itoh, K. Takatsu.
Adhesion molecules on eosinophils in acute eosinophilic pneumonia.
Am J Respir Crit Care Med, 151 (1995), pp. 1259-1262
[21.]
K. Oshikawa, K. Kuroiwa, T. Tokunaga, T. Kato, S.I. Hagihara, S.I. Tominaga, Y. Sugiyama.
Acute eosinophilic pneumonia with increased soluble st2 in serum and bronchoalveolar lavage fluid.
Respir Med, 95 (2001), pp. 532-533
[22.]
H. Taniguchi, J. Kadota, T. Fujii, Y. Matsubara, S. Katoh, H. Mukae, S. Matsukura, S. Kohno.
Activation of lymphocytes and increased interleukin-5 levels in bronchoalvcolar lavage fluid in acute eosinophilic pneumonia.
Eur Respir J, 13 (1999), pp. 217-220
[23.]
V.L. Buddharaju, J.L. Saraceno, J.M. Rosen, K.S.D. Spiva, T.C. Smith, R. Ilves, D.A. Killam, B.J. Mckena.
Acute eosinophilic pneumonia associated with shock.
Crit Care Med, 27 (1999), pp. 2014-2016
[24.]
M.A. King, A.L. Pope-Harman, J.N. Allen, G.A. Christoforidis, A.J. Christo Foridis.
Acute Eosinophilic Pneumonia: radiologic and clinical features.
Radiology, 203 (1997), pp. 715-719
[25.]
P. Dejaegher, L. Derveuax, I.S.P. Dubo, M. Demedts.
Eos inophilic pneumonia without radiographic pulmonary infiltrates.
Chest, 84 (1983), pp. 637-638
[26.]
P. Dejaegher, M. Demedts.
BAL in eosinophilic pneumonia before and during corticosteroid therapy.
Am Rev Respir Dis, 129 (1984), pp. 631-632
[27.]
H.D. Tazelaar, L.J. Linz, T.V. Colby, J.L. Myers, A.H. Limper.
Acute eosinophilic pneumonia: histopathologic findings in nine patients.
Am J Respir Crit Care Med, 155 (1997), pp. 296-302
[28.]
J. Buchheit, N. Eid, G. Rodgers, T. Feger, O. Yakoub.
Acute eosinophilic pneumonia with respiratory failure: a new syndrome?.
Am Rev Respir Dis, 145 (1992), pp. 716-718
[29.]
L.C. Altman, J.S. Hill, W.M. Hairfield, M.F. Mullarkey.
Effects of corticosteroids on eosinophilic chemotaxis and adherence.
J Clin Invest, 67 (1981), pp. 28-36
Copyright © 2002. Sociedade Portuguesa de Pneumologia/SPP
Download PDF
Pulmonology
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?