Journal Information
Vol. 11. Issue 1.
Pages 63-66 (January - February 2005)
Share
Share
Download PDF
More article options
Vol. 11. Issue 1.
Pages 63-66 (January - February 2005)
Caso Clínico\Clinical Case
Open Access
Pneumonia pelo vírus influenza B pós-transplante de medula óssea: relato de caso com ênfase dos achados de tomografia computadorizada de alta resolução
Influenza B virus pneumonia after bone marrow transplantation: case report with emphasis to the high resolution computed tomography findings
Visits
5612
Emerson L. Gasparetto1, Ricardo C. Cavalli2, Gabriela de Melo Rocha2, João Falavigna2, Taisa Davaus2, Dante L. Escuissato3, Edson Marchiori4
1 Médico Residente do Hospital de Clínicas da Universidade Federal do Paraná, Curitiba, PR.
2 Académicos de Medicina da Universidade Federal do Paraná, Curitiba, PR.
3 Professor Assistente da Disciplina de Radiologia Médica da Universidade Federal do Paraná, Curitiba, PR.
4 Professor Titular de Radiologia da Universidade Federal Fluminense e Coordenador Adjunto do Curso de Pós-Graduação da Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ.
This item has received

Under a Creative Commons license
Article information
Resumo

Doente do sexo masculino, 9 anos, transplantado de medula óssea devido leucemia mielóide aguda, apresentou febre e tosse seca três dias após o procedimento. A radiografia de tórax demonstrou infiltrado reticular difuso bilateral. A tomografia computadorizada de alta resolução do tórax revelou espessamento do interstício peribroncovascular, pequenos nódulos centrolobulares periféricos e áreas de atenuação em vidro fosco. O lavado broncoalveolar demonstrou pesquisa positiva por imunofluorescência direta para anticorpos anti-vírus influenza B. Foi instituído tratamento com ribavirina aerolizada durante 10 dias com melhoria clínico-radiológica do quadro infeccioso.

Rev Port Pneumol 2005; XI (1): 63-66

Palavras-chave:
Vírus influenza B
tomografia computadorizada de alta resolução
transplante de medula óssea
Abstract

Nine year-old male patient, who underwent bone marrow transplantation because of acute myelogenous leukemia, presented with fever and dry cough three days after the procedure. The chest radiograph demonstrated bilateral diffuse reticular infiltrate. The high resolution computed tomography showed peribronchovascular interstitial thickening, peripheral small centrilobular nodules and areas of ground-glass attenuation. The bronchoalveolar lavage demonstrated positive direct fluorescence antibody testing against influenza B virus. Treatment with aerolizated ribavirin was instituted during 10 days and the patient showed clinical-radiological improvement.

Rev Port Pneumol 2005; XI (1): 63-66

Key-words:
Influenza B virus
high resolution computed tomography
bone marrow transplantation
Full text is only aviable in PDF
Bibliografia
[1.]
J. Aschan, O. Ringden, P. Ljungman, J. Andersson, I. Lewensohn-Fuchs, M. Forsgren.
Influenza B in transplant patients.
Scand J Infect Dis, 21 (1989), pp. 349-350
[2.]
Escuissato DL, Aguiar ROC, Gasparetto EL, Muller NL. Disseminated toxoplasmosis after bone marrow transplantation: Pulmonary manifestations on High -Resolution CT in one patient. J Thorac Imaging (in press).
[3.]
R.H. Wise Jr., M.S. Shin, J.P. Gockerman, S.L. Zornes, E. Rubin, P.H. Nath.
Pneumonia in bone marrow transplant patients.
AJR, 143 (1984), pp. 707-714
[4.]
R.A. Bowden.
Respiratory virus infections after marrow transplant: The Fred Hutchinson Cancer Research Center experience.
Am J Med, 102 (1997), pp. 27-30
[5.]
E. Whimbey, R.E. Champlin, R.B. Couch, et al.
Community respiratory virus infections among hospitalized adult bone marrow transplant recipients.
Clin Infect Dis, 22 (1996), pp. 778-782
[6.]
P. Ljungman, C.A. Gleaves, J.D. Meyers.
Respiratory virus infection in immunocompromised patients.
Bone Marrow Transplant, 4 (1989), pp. 35-40
[7.]
P. Ljungman.
Respiratory virus infections in bone marrow transplant recipients: The European Perspective.
Am J Med, 102 (1997), pp. 44-47
[8.]
H.T. Winer-Muram, J.W. Gurney, P.M. Bozeman, R.A. Krance.
Pulmonary complications after bone marrow transplantation.
Radiol Clin North Am, 34 (1996), pp. 97-117
[9.]
T.M. Wah, H.A. Moss, R.J. Robertson, D.L. Barnard.
Pulmonary complications following bone marrow transplatation.
Br J Radiol, 76 (2003), pp. 373-379
[10.]
G. McGuinness, J.F. Gruden.
Viral and Pneumocystis carinii infections of the lung in the immunocompromised host.
J Thorac Imaging, 14 (1999), pp. 25-36
[11.]
E.L. Gasparetto, D.L. Escuissato, E. Marchiori, S. Ono, R.L. Frare e Silva, N.L. Müller.
High-Resolution CT Findings of Respiratory Syncytial Virus Pneumonia After Bone Marrow Transplantation.
AJR, 182 (2004), pp. 1133-1137
[12.]
Gasparetto EL, Ono SE, Escuissato DL. et al. Cytomegalovirus pneumonia after bone marrow transplantation: high-resolution CT findings. Br J Radiol (in press).
[13.]
A.N. Leung, M.V. Gosselin, C.H. Napper, S.G. Braun, W.W. Hu, R.M. Wong, J. Gasman.
Pulmonary Infections after bone marrow transplantation: Clinical and radiographic findings.
[14.]
E.A. Kim, K.S. Lee, S.L. Primack, H.K. Yoon, H.S. Byun, T.S. Kim, Gy Suh, O.J. Kwon, J. Han.
Viral pneumonia in adults: Radiologic and pathologic findings.
[15.]
A. Oikonomou, N.L. Müller, S. Nantel.
Radiographic and High-Resolution CT findings of influenza virus pneumonia in patients with hematologic malignancies.
Copyright © 2005. Sociedade Portuguesa de Pneumologia/SPP
Download PDF
Pulmonology
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?