Resistência aos antibacilares

Gomes, Carlos; Mendes, Berta; Pina, Jaime; Marques Gomes, M.J.

doi:10.1016/S0873-2159(15)31042-4

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RESUMO

Neste trabalho abordamos o fenómeno da resistência aos antibacilares explícitando conceitos, mecanismos, tipos de resistências e suas implicações em termos de significado para a compreensão dos indicadores epidemiológicos.

Revemos, também, os problemas relacionados com a metodologia laboratorial e, por último, abordamos as estratégias de prevenção e os resultados obtidos pelo Programa de Vigilância Global da OMS, particularizando a situação em Portugal.

REV PORT PNEUMOL 1998; IV (2): 155-163

Palavras-chave:

Tuberculose multirresistente

Epidemiologia

Prevenção de resistências

SUMMARY

We rewied the problem of multidrug resistance to antimycobacterial drugs, adressing different aspects according to the epidemiological significance by reweing its concepts and mechanisms.

We also refer to the WHO/IUATLD Global Project on Antituberculosis Drug-Resistance Surveillance, with special emphasis to the results reported in Portugal, discussing the prevention strategies and the problems related to the laboratory methodology.

REV PORT PNEUMOL 1998; IV (2): 155-163

Key-words:

Multidrug-resistant tuberculosis

Epidemiology

Prevention of resistance

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