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Vol. 16. Issue 5.
Pages 759-777 (September - October 2010)
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Vol. 16. Issue 5.
Pages 759-777 (September - October 2010)
Artigo Original/Original Article
Open Access
Risco de reinternamento na doença pulmonar obstrutiva crónica – Estudo prospectivo com ênfase no valor da avaliação da qualidade de vida e depressão
Risk factors for readmission after hospital discharge in chronic obstructive pulmonary disease. The role of quality of life indicators
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Rui Carneiro1,
Corresponding author
ruicarneiro77@gmail.com

Correspondência/Correspondence to: Rui Carneiro, Hospital de Santo António, Serviço de Medicina Interna, Largo Prof. Abel Salazar, 4099-001 porto
, Cristiana Sousa1, Alexandre Pinto1, Fernanda Almeida2, Júlio R. Oliveira2, Nelson Rocha3
1 Interno Complementar de Medicina Interna/Resident, Internal Medicine
2 Assistente Hospitalar de Medicina Interna/Consultant, Internal Medicine
3 Chefe de Serviço de Medicina Interna/Head, Internal medicine Unit
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Resumo

O objectivo do estudo é identificar factores demográficos, clínico-funcionais e inerentes à qualidade de vida (QV) e depressão, com impacto na utilização do Serviço de Urgência (SU) e nos reinternamentos após alta hospitalar por agudização de doença pulmonar obstrutiva crónica (DPOC) num período de 66 semanas. A QV foi avaliada pelo St. George Respiratory Questionnaire (SGRQ). A Beck Depression Inventory avaliou a depressão.

Avaliámos prospectivamente 45 doentes (84,4% homens; mediana de idades: 73 anos; estádio IV:51%). A mediana do score total do SGRQ foi de 50,6, sendo maior o impacto dos sintomas, principalmente nos mais jovens (r:-0425; p:0,043), e da limitação à actividade do que o impacto emocional. Mais de metade encontravam-se deprimidos. Pior QV associou-se a depressão (R:0,699;p:0,02). Valores baixos do VEMS correlacionaram -se com a depressão (r=-0,46;p=0,054) mas não com QV. A prescrição de anticolinérgicos de longa acção ou corticóides inalatórios melhoraram a QV. Quase 85% dos doentes recorreram ao SU (25,8% por DPOC agudizada). A taxa de reinternamento por todos os motivos e por DPOC agudizada foi de 64,9% e 33,3% (por unidade de tempo). O número de reinternamentos (todos os motivos) correlacionou-se com a idade (R=0,48; p=0,003), cor pulmonale (R=-0,46; p=0,03) e com a QV (R=0,67 p=0,004). Doentes deprimidos (R=0,51; p=004), com VEMS baixo (R=-0,413; p=0,04) e com cor pulmonale (R=-046;p=0,005) estiveram mais dias internados por agudização da DPOC. A QV e a depressão são variáveis a considerar na avaliação e tratamento de doentes com DPOC, fazendo parte dum conjunto de dados clínicos, analíticos e funcionais que podem predizer o risco de reinternamento após alta por DPOC agudizada.

Rev Port Pneumol 2010; XVI (5): 759-777

Palavras-chave:
Doença pulmonar obstrutiva crónica
qualidade de vida
depressão
internamento
Abstract

Aims: To identify demographic, clinical, functional and inherent quality of life (QOL) and depression factors with impact on use of the Emergency Services (ES) or readmission after hospital discharge for acute exacerbation of chronic obstructive pulmonary disease (COPD) over a period of 66 weeks. QOL was evaluated by the St. George’s Respiratory Questionnaire (SGRQ). The Beck Depression Inventory assessed depression.

We prospectively evaluated 45 patients (84.4% male, median age 73 years, stage IV 51%). The median total SGRQ score was 50.6, with a greater impact on symptoms, especially in younger patients (r=-0.425; p=0.043), and activity limitation than emotional impact of the disease. More than half were depressed. Worse QOL meant depression (R=0.699; p=0.02). Low FEV1 correlated with depression (r=-0.46; p =0.05) but not with QOL. Long-acting anti-cholinergic bronchodilator and inhaled steroids improved QOL. Almost 85% of patients used ES (25.8% for exacerbated COPD). Rate of hospital readmission for all reasons and exacerbated COPD was 64.9% and 33.3%. The number of readmissions (all reasons) was correlated with age (R=0.48; p=0003), cor pulmonale (R=-0.46; p=0.03) and QOL (R=0.67; p=0.004). Depressed patients (R=0.51; p=004), with low FEV1 (R=-0413; p=0.04) and with cor pulmonale (R=-046, p=0.005) had more inhospital days for exacerbation of COPD.

QOL and depression are variables to consider in the evaluation and treatment of patients with COPD as part of a set of clinical and functional data that can predict the risk of readmission after hospital discharge for exacerbated COPD.

Rev Port Pneumol 2010; XVI (5): 759-777

Key-words:
Chronic obstructive pulmonary disease
quality of life
depression
admission to hospital
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Bibliografia/Bibliography
[1.]
Direcção-Geral da Saúde.
(5 de Maio de 2005)www.dgs.pt
[2.]
F. Anderson, S. Borg, S.A. Jansson, et al.
The costs of exacerbations in chronic obstructive pulmonary disease.
Resp Med, 96 (2002), pp. 700-708
[3.]
R. Curtis, D. Martin, T. Martin.
Patient-assessed health outcomes in chronic lung disease: what are they, how do they help us and where do we go from here?.
Am J Resp Crit Care Med, 156 (1997), pp. 1032-1039
[4.]
A. Stewart, R. Greenfield, R. Hayes, et al.
Functional status and well-being of patients with chronic conditions: results from the medical outcomes study.
JAMA, 262 (1989), pp. 907-913
[5.]
J. Gore, C. Brophy, M. Greenstone.
How well do we care for patients with end stage chronic obstructive pulmonary disease (COPD)? A comparison of palliative and quality of life in COPD and lung cancer.
Thorax, 55 (2000), pp. 1000-1006
[6.]
G. Gudmundsson, T. Gislason, C. Janson, et al.
Risk factors for rehospitalization in COPD: role of health status, anxiety and depression.
Eur Respir J, 26 (2005), pp. 414-419
[7.]
V. Fan, J. Curtis, S.-P. Tu, M. Mcdonell, S. Fihn.
Using quality of life to predict hospitalization and mortality with obstructive lung diseases.
Chest, 122 (2002), pp. 429-436
[8.]
G. Gudmundsson, T. Gislason, C. Janson, et al.
Depression, anxiety and health status after hospitalization for COPD: a multicentre study in the Nordic countries.
Respir Med, 100 (2006), pp. 87-93
[9.]
S. Kim, C. Emerman, R. Cydulka, et al.
Prospective multicenter study of relapse following emergency department treatment of COPD exacerbation.
Chest, 125 (2004), pp. 473-481
[10.]
G. Gudmundsson, T. Gislason, Lindberg, et al.
Mortality in COPD patients discharged from hospital: the role of treatment and co-morbidity.
Respiratory Research, 7 (2006), pp. 109-118
[11.]
Global Initiative for Chronic Obstructive Lung Disease: Global Strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease.
[12.]
P.W. Jones, F.H. Quirk, C.M. Baveystock, O.A. Littlejohns.
Self-complete measure of health status for chronic airflow limitation. The St. George’s Respiratory Questionnaire.
Am Rev Respir Dis, 145 (1992), pp. 1321-1327
[13.]
Beck AT, et al. Short form of depression inventory: cross-validation. Psychological Reports 34(3):1184.
[14.]
M. Graffar.
Une méthode de classification social d’échantillons de population.
Courier CIE, 6 (1956), pp. 445
[15.]
K. Groenewegen, A. Schols, E. Wouters.
Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD.
Chest, 124 (2003), pp. 459-467
[16.]
N. Dewan, S. Rafique, B. Kanwar, et al.
Acute exacerbation of COPD: factors associated with poor treatment outcome.
Chest, 117 (2000), pp. 662-671
[17.]
P. Wongsurakiat, K. Maranetra, C. Wasi, U. Kositanont, W. Dejsomritrutai, S. Charoenratanakus.
Acute respiratory illness in patients with COPD and the effectiveness of influenza vaccination: a randomized controlled trial.
Chest, 125 (2004), pp. 2011-2020
[18.]
L. Jakson, K. Neuzil, O. Yu, P. Benson, W. Barlow, A. Adams, et al.
Effectiveness of pneumococcal polysaccharide vaccine in older adults.
N Engl J Med, 348 (2003), pp. 1138-1380
[19.]
J. Garcia-Aymerich, E. Farrero, M. Félez, J. Izquierdo, et al.
Risk factors of readmission to hospital for a COPD exacerbation: a prospective study.
Thorax, 58 (2003), pp. 100-105
[20.]
F. Álvarez-Gutierrez, M. Miravitlles, M. Calle, E. Gobartt, et al.
Impacto de la EPOC en la vida diaria de los pacientes. Resultados del estudio multicéntrico EIME.
Arch Bronconeumol, 43 (2007), pp. 64-72
[21.]
S. Shepperd, J. Parkes, J.J.M. Mcclaran, C. Phillips.
Discharge planning from hospital to home.
Cochrane Database of Systematic Reviews, (2004),
[22.]
J. Maurer, V. Rebbapragada, S. Borson, et al.
Anxiety and depression in COPD: current understanding, unanswered questions and research needs.
Chest, 134 (2008), pp. 43S-56S
[23.]
J. Solano, B. Gomes, I. Higginson.
A comparison of symptom prevalence in far advanced cancer, AIDS, heart failure, chronic obstructive pulmonary disease and renal disease.
J Pain Symptom Manage, 31 (2006), pp. 58-69
[24.]
J. Van Manen, J.P. Bindels, F. Dekker, Ijzermans, J. VAN Der Zee, E. Schade.
Risk of depression in patients with chronic obstructive pulmonary disease an its determinants.
Thorax, 57 (2002), pp. 412-416
[25.]
TORCH study group: The TORCH (Towards a revolution in COPD health). Survival study protocol.
Eur Resp J, 24 (2004), pp. 206-210
[26.]
P. Ammagro, E. Clabo, E. Ochoa, et al.
Mortality after hospitalization for COPD.
Chest, 121 (2002), pp. 1441-1448
[27.]
P.A. Mckee, W.P. Castelli, P.M. Mcnamara, W.B. Kannel.
The natural history of congestive heart failure: the Framingham study.
N Engl J Med, 285 (1971), pp. 1441-1446
[28.]
Nathan D, Buse J, Davidson M, Ferrannini E, et al. Medical Management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy. Diabetes Care 2088; 31:1-11.
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