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Vol. 1. Issue 3.
Pages 241-246 (May - June 1995)
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Vol. 1. Issue 3.
Pages 241-246 (May - June 1995)
CASO CLÍNICO
Open Access
Terapêutica com metotrexato na sarcoidose
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I. Pascoal*, J.C. Winck**, A. Carvalho***, F.F. Rodrigues***
* Interna de Pneumologia, Serviço de Pneumologia A, Departamento de Pneumologia do Centro Hospitalar de VN Gaia
** Assistente Eventual de Pneumologia, Serviço de Pneumologia A, Departamento de Pneumologia do Centro Hospitalar de VN Gaia
*** Assistentes Graduados de Pneumologia, Serviço de Pneumologia A, Departamento de Pneumologia do Centro Hospitalar de VN Gaia
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RESUMO

Os autores descrevem um caso clínico de um homem de 33 anos com sarcoidose estádio II, em que, durante corticoterapia de longo curso surge osteonecrose da cabeça do fémur direito. Devido a este efeito secundário, foi iniciada terapêutica com metotrexato, com melhoria clínica e funcional. São também discutidas as indicações da corticoterapia e analisada a experiência com a utilização do metotrexato na sarcoidose.

Palavras-chave:
Sarcoidose
osteonecrose
corticoterapia
metotrexato
ABSTRACT

The authors describe a case of a 33 year old male with stage II sarcoidosis, developping osteonecrosis of the right femoral head while on long term corticosteroids. Due to this severe side-effect, methotrexate was introduced, with significant clinical/functional improvement The role of corticosteroids in this setting are analysed as well as the experience with methotrexate in sarcoidosis.

Key-Words:
Sarcoidosis
osteonecrosis
corticosteroids
methotrexate
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Copyright © 1995. Sociedade Portuguesa de Pneumologia/SPP
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