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Vol. 15. Issue 2.
Pages 325-329 (March - April 2009)
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Vol. 15. Issue 2.
Pages 325-329 (March - April 2009)
Caso Clínico/Case Report
Open Access
Tuberculose miliar e febre Q em doente imunocompetente
Miliary tuberculosis and Q fever in an immunocompetent patient
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Sandra Simões1, Arsénio Santos2, Teresa Vaio3, Sara Leitão2, Rui M. Santos4, Nascimento Costa5
1 Interna do Internato Complementar de Medicina Interna
2 Assistente Graduado(a) de Medicina Interna
3 Assistente de Medicina Interna
4 Chefe de Serviço de Medicina III e Professor Auxiliar da Faculdade de Medicina da Universidade de Coimbra
5 Director de Serviço de Medicina III e Professor Catedrático da Faculdade de Medicina da Universidade de Coimbra
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Resumo

A tuberculose miliar é a forma de doença progressiva resultante da disseminação hematogénea maciça do Mycobacterium tuberculosis (MT). Afecta imunode-primidos e idosos e tem manifestações clínicas insi-diosas e inespecíficas. O caso clínico descrito refere-se a um homem adulto, sem imunodeficiência, com in-fecção simultânea por Coxiella burnetti e MT.

A raridade desta associação e a sua forma de apresen-tação sublinham a necessidade de alto grau de suspei-ção clínica para a formulação dos diagnósticos, sendo este o segundo caso descrito na literatura.

Rev Port Pneumol 2009; XV (2): 325-329

Palavras-chave:
Tuberculose miliar
febre Q
tratamento
Abstract

Miliary tuberculosis is a progressive disease resulting from the massive hematogeneous dissemination of Mycobacterium tuberculosis. Immunocompromised and elderly patients are the most affected. A case of an immunocompetent 45 year old man, with miliary tuberculosis and a simultaneous infection by Coxiella burnetti is presented.

The clinical presentation demands a high awareness for the presence of tuberculosis. The rarity of this association, only one case reported in literature, appears to be a fortuity coincidence.

Rev Port Pneumol 2009; XV (2): 325-329

Key-words:
Miliary tuberculosis
Q fever
treatment
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Referências
[1.]
C. Dye.
Global epidemiology of tuberculosis.
[2.]
J. Pina, et al.
A tuberculose no virar do milénio, 1.ª ed, pp. 3-575
[3.]
G. Salvado, et al.
Tuberculose miliar. Revisão de casos internados numa unidade de tuberculose.
Rev Port Pneumol, 8 (2002), pp. 315-327
[4.]
N. Basgoz.
Clinical manifestations, diagnosis and treatment of miliary tuberculosis.
(2007),
[5.]
J. Kim, A. Langston, H. Gallis.
Miliary tuberculosis: epidemiology, clinical manifestations, diagnosis and outcome.
Rev Infect Dis, 12 (1990), pp. 583-590
[6.]
D. Raoult.
Clinical features, diagnosis, treatment and prevention of Q fever.
(2007),
[7.]
D.H. Walker, S. Dumler, T. Marrie.
Diseases caused by Rickettsiae, Mycoplasmas and Chlamydiae, Harrisson´s Principals of Internal Medicine, pp. 1066-1067
[8.]
G. Maartens, P. Willcox, S. Benatar.
Miliary tuberculosis: rapid diagnosis, hematologic abnormalities and outcome in 109 treated adults.
Am J Med, 89 (1990), pp. 291-296
[9.]
E. Corbett, et al.
The growing burden of tuberculosis, global trends and interactions with the HIV epidemic.
Arch Intern Med, 163 (2003), pp. 1009-1021
[10.]
R. Optican, A. Ost, C. Ravin.
High-resolution computed tomography in the diagnosis of miliary tuberculosis.
Chest, 102 (1992), pp. 941-943
[11.]
J. Garcia, et al.
Hepatic granulomatosis caused by Q fever: a cause of erroneous tuberculosis diagnosis.
An Med Interna, 10 (1993), pp. 595-598
[12.]
A. Watanabe.
Clinical manifestation of Q fever and tuberculosis, similarly caused by intracellular parasites.
Kekkaku, 81 (2006), pp. 543-549
[13.]
Y. Sumida, et al.
A case of military tuberculosis complicating acute Q fever.
Nippon Shokakibyo Gakkai Zasshi, 103 (2006), pp. 1377-1383
Copyright © 2009. Sociedade Portuguesa de Pneumologia/SPP
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