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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Asthma exacerbations during pregnancy&#58; incidence and association with adverse pregnancy outcomes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "V&#46;E&#46; Murphy"
                            1 => "V&#46;L&#46; Clifton"
                            2 => "P&#46;G&#46; Gibson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/thx.2005.049718"
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "2006"
                        "volumen" => "61"
                        "paginaInicial" => "169"
                        "paginaFinal" => "176"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16443708"
                            "web" => "Medline"
                          ]
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              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Brum G&#46; Gravidez-complica&#231;&#245;es pulmonares&#46; 39&#46;&#176; Curso de Pneumologia para p&#243;s-graduados&#46; Patologia respirat&#243;ria na mulher&#44; que diferen&#231;as&#63; Cl&#237;nica de Pneumologia&#46; FML&#47;HSM&#46; 30 Mar&#231;o a 1 de Abril de 2006&#59; 145-51&#46;"
                ]
              ]
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            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Freitas MG&#44; Amaral Marques R&#44; Ponce P&#46; Asma br&#244;nquica&#46; Manual de Terap&#234;utica M&#233;dica 1&#46; Lidel Edi&#231;&#245;es T&#233;cnicas&#44; Lda&#46; 2002&#59; 45-54&#46;"
                ]
              ]
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              "etiqueta" => "15&#46;"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "How we manage venous thromboembolism during pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46;M&#46; Bates"
                            1 => "J&#46;S&#46; Ginsberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1182/blood-2002-03-0965"
                      "Revista" => array:7 [
                        "tituloSerie" => "Blood"
                        "fecha" => "2002"
                        "volumen" => "100"
                        "numero" => "10"
                        "paginaInicial" => "3470"
                        "paginaFinal" => "3478"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12393666"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diagnosis of suspected venous thromboembolic disease in pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46;F&#46; Scarsbrook"
                            1 => "A&#46;L&#46; Evans"
                            2 => "A&#46;R&#46; Owen"
                            3 => "F&#46;V&#46; Gleeson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.crad.2005.08.015"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Radiol"
                        "fecha" => "2006"
                        "volumen" => "61"
                        "paginaInicial" => "1"
                        "paginaFinal" => "12"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16356811"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
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              "identificador" => "bib17"
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "MSc&#46; Sex and gender issues and venous thromboembolism"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Lisa"
                            1 => "L&#46;B&#46; Kathry"
                            2 => "M&#46; Susan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ccm.2004.01.013"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Chest Med"
                        "fecha" => "2004"
                        "volumen" => "25"
                        "paginaInicial" => "281"
                        "paginaFinal" => "297"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15099889"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary embolism during and after pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Stone"
                            1 => "T&#46;A&#46; Morris"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:8 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2005"
                        "volumen" => "33"
                        "numero" => "10 suppl"
                        "paginaInicial" => "S294"
                        "paginaFinal" => "S299"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16215350"
                            "web" => "Medline"
                          ]
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                        "itemHostRev" => array:3 [
                          "pii" => "S009042950101562X"
                          "estado" => "S300"
                          "issn" => "00904295"
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                  ]
                ]
              ]
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              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Monteiro JT&#46; Tromboembolismo pulmonar&#58; Aspectos particulares&#46; 39&#46;&#176; Curso de Pneumologia para p&#243;s-graduados&#46; Patologia respirat&#243;ria na mulher&#44; que diferen&#231;as&#63; Cl&#237;nica de Pneumologia&#46; FML&#47;HSM&#46; Lisboa&#44; 2006&#59; 115-7&#46;"
                ]
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              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Maternal plasma D-dimer levels in normal and complicated pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "T&#46;E&#46; Nolan"
                            1 => "R&#46;P&#46; Smith"
                            2 => "L&#46;D&#46; Devoe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Obstet Gynecol"
                        "fecha" => "1993"
                        "volumen" => "81"
                        "paginaInicial" => "235"
                        "paginaFinal" => "238"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8423957"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Management of thromboembolic disease in pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "L&#46;K&#46; Tan"
                            1 => "M&#46; Swiet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Acad Med Singapore"
                        "fecha" => "2002"
                        "volumen" => "31"
                        "paginaInicial" => "311"
                        "paginaFinal" => "319"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12061291"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Practical Nuclear Medicine"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46;L&#46; Palmer"
                            1 => "J&#46;A&#46; Scott"
                            2 => "H&#46;W&#46; Strauss"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1992"
                        "editorial" => "WB Saunders"
                        "editorialLocalizacion" => "Philadelphia"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Goldhaber SZ&#46; Pulmonary Embolism&#46; Medical Progress&#46; 339&#40;2&#41;&#58;93-104&#46;"
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Massive pulmonary embolism in pregnancy treated with tissue plasminogen activator"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "E&#46; Trukhacheva"
                            1 => "M&#46; Scharff"
                            2 => "M&#46; Gardner"
                            3 => "N&#46; Lakkis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.AOG.0000164059.72933.9c"
                      "Revista" => array:7 [
                        "tituloSerie" => "Obstet Gynecol"
                        "fecha" => "2005"
                        "volumen" => "106"
                        "numero" => "5 Pt 2"
                        "paginaInicial" => "1156"
                        "paginaFinal" => "1158"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16260552"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib25"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Amniotic fluid embolism"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Moore"
                            1 => "M&#46;R&#46; Baldisseri"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2005"
                        "volumen" => "33"
                        "numero" => "10 suppl"
                        "paginaInicial" => "S279"
                        "paginaFinal" => "S284"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16215348"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Exacerbation of underlying pulmonary disease in pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "B&#46;M&#46; Marie"
                            1 => "A&#46;C&#46; Arroliga"
                            2 => "S&#46; Emery"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2005"
                        "volumen" => "33"
                        "numero" => "10 suppl"
                        "paginaInicial" => "S313"
                        "paginaFinal" => "S321"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16215353"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
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              "identificador" => "bib27"
              "etiqueta" => "27&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Martins Correia J&#46; Hipertens&#227;o Pulmonar&#46; In&#58; Maria Jo&#227;o Marques Gomes&#44; R Sotto-Mayor &#40;eds&#41;&#58; Tratado de Pneumologia&#46; Vol II&#46; SPP&#46; 1599-626&#46;"
                ]
              ]
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              "etiqueta" => "28&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pregnancy outcome in patients with pulmonary arterial hypertension Receiving prostacyclin therapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "D&#46; Bendayan"
                            1 => "M&#46; Hold"
                            2 => "G&#46; Oron"
                            3 => "A&#46; Sagie"
                            4 => "L&#46; Eidelman"
                            5 => "D&#46; Shitrit"
                            6 => "M&#46;R&#46; Kramer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Obstetrics and Gynecology"
                        "fecha" => "2005"
                        "volumen" => "106"
                        "numero" => "5"
                      ]
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                ]
              ]
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              "etiqueta" => "29&#46;"
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                  "referenciaCompleta" => "Mendes AC&#46; Doen&#231;as vasculares do pulm&#227;o&#46; 39&#46;&#176; Curso de Pneumologia para p&#243;s-graduados&#46; Patologia respirat&#243;ria na mulher&#44; que diferen&#231;as&#63; Cl&#237;nica de Pneumologia&#46; FML&#47;HSM&#46; Lisboa&#44; 2006&#59; 115-7&#46;"
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              ]
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              "identificador" => "bib30"
              "etiqueta" => "30&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The use of iloprost in early pregnancy in patients with pulmonary arterial hypertension"
                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:10 [
                            0 => "C&#46;A&#46; Elliot"
                            1 => "P&#46; Stewart"
                            2 => "V&#46;J&#46; Webster"
                            3 => "G&#46;H&#46; Mills"
                            4 => "S&#46;P&#46; Hutchinson"
                            5 => "E&#46;S&#46; Howarth"
                            6 => "F&#46;A&#46; Bu&#8217;lock"
                            7 => "R&#46;A&#46; Lawson"
                            8 => "I&#46;J&#46; Armstrong"
                            9 => "D&#46;G&#46; Kiely"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Eur Respir Journ"
                        "fecha" => "2005"
                        "volumen" => "26"
                        "paginaInicial" => "168"
                        "paginaFinal" => "173"
                      ]
                    ]
                  ]
                ]
              ]
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              "identificador" => "bib31"
              "etiqueta" => "31&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Carro-Jim&#233;nez EJ&#44; Lopez JE&#46; Primary pulmonary hypertension and pregnancy&#46; Bol Assoc Med PR 97&#40;4&#41;&#58;328-33&#46;"
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib32"
              "etiqueta" => "32&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Intravenous and Inhaled Epoprostenol for primary pulmonary hypertension during pregnancy and delivery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "I&#46; Bildirici"
                            1 => "J&#46;B&#46; Shumway"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Obstetrics and Gynecology"
                        "fecha" => "2004"
                        "volumen" => "3"
                        "numero" => "5"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13154780"
                            "web" => "Medline"
                          ]
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                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib33"
              "etiqueta" => "33&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary vascular disease and pregnancy&#58; current controversies&#44; management strategies perspectives&#46;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "B&#46;M Weiss"
                            1 => "O&#46;M&#46; Hess"
                          ]
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1053/euhj.1999.1701"
                      "Revista" => array:7 [
                        "tituloSerie" => "Eur Heart J"
                        "fecha" => "2000"
                        "volumen" => "21"
                        "numero" => "2"
                        "paginaInicial" => "104"
                        "paginaFinal" => "115"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10637084"
                            "web" => "Medline"
                          ]
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                    ]
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                ]
              ]
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              "identificador" => "bib34"
              "etiqueta" => "34&#46;"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Successful Management of Pregnancy in a Patient with Eisenmerger Syndrome With Epoprostenol"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Geohas"
                            1 => "V&#46;V&#46; McLaughlin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2003"
                        "volumen" => "124"
                        "paginaInicial" => "1170"
                        "paginaFinal" => "1173"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12970054"
                            "web" => "Medline"
                          ]
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                      ]
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                  ]
                ]
              ]
            ]
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              "etiqueta" => "35&#46;"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A comparison of continuous intravenous Epoprostenol with conventional therapy for primary pulmonary hypertension"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:4 [
                            0 => "R&#46;J&#46; Barst"
                            1 => "L&#46;J&#46; Rubin"
                            2 => "W&#46;A&#46; Long"
                            3 => "S&#46; Rich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "N Eng J Med"
                        "fecha" => "1996"
                        "volumen" => "334"
                        "paginaInicial" => "22"
                        "paginaFinal" => "301"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib36"
              "etiqueta" => "36&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acute respiratory distress syndrome in pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;E&#46; Cole"
                            1 => "T&#46;L&#46; Taylor"
                            2 => "D&#46;M&#46; McCullough"
                            3 => "C&#46;T&#46; Shoff"
                            4 => "S&#46; Derdak"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2005"
                        "volumen" => "33"
                        "numero" => "10 suppl"
                        "paginaInicial" => "S269"
                        "paginaFinal" => "S276"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16215347"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bib37"
              "etiqueta" => "37&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Student&#46; Arterio-venous malformation of the lung in pregnancy with massive haemoptysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46; Fatimi"
                            1 => "S&#46; Sheikh"
                            2 => "S&#46;F&#46; Khan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "IJTCVS"
                        "fecha" => "2005"
                        "volumen" => "21"
                        "paginaInicial" => "281"
                        "paginaFinal" => "282"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            37 => array:3 [
              "identificador" => "bib38"
              "etiqueta" => "38&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pneumonia in pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46;S&#46; Ramsey"
                            1 => "K&#46;D&#46; Ramin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Obstet Gynecol Clin North Am"
                        "fecha" => "2001"
                        "paginaInicial" => "28"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            38 => array:3 [
              "identificador" => "bib39"
              "etiqueta" => "39&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Treatment of community-acquired lower respiratory tract infections during pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "W&#46;S&#46; Lim"
                            1 => "J&#46;T&#46; Macfarlane"
                            2 => "C&#46;L&#46; Colthorpe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Respir Med"
                        "fecha" => "2003"
                        "volumen" => "2"
                        "numero" => "3"
                        "paginaInicial" => "221"
                        "paginaFinal" => "233"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14720004"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            39 => array:3 [
              "identificador" => "bib40"
              "etiqueta" => "40&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Airway problems in pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "U&#46; Munnur"
                            1 => "B&#46; Boisblanc"
                            2 => "M&#46;S&#46; Suresh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2005"
                        "volumen" => "33"
                        "numero" => "10 supp"
                        "paginaInicial" => "S259"
                        "paginaFinal" => "S267"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16215346"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            40 => array:3 [
              "identificador" => "bib41"
              "etiqueta" => "41&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Ely JW&#44; Jerome Y&#44; Noelle B&#46; Evaluation of Pregnant Womem Exposed to Respiratory Virus&#46; American Family Physician&#46; American Academy of Family Physicians&#46; 2000&#46;"
                ]
              ]
            ]
            41 => array:3 [
              "identificador" => "bib42"
              "etiqueta" => "42&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Wheat LJ&#46; Systemic Fungal Infection During Pregnancy&#46; Case Study 2005A&#46;"
                ]
              ]
            ]
            42 => array:3 [
              "identificador" => "bib43"
              "etiqueta" => "43&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Invasive Pulmonary Aspergillosis in a Puerperant with Drug induced Agranulocytosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:10 [
                            0 => "F&#46; Aoki"
                            1 => "Y&#46; Sando"
                            2 => "S&#46; Tajima"
                            3 => "K&#46; Imai"
                            4 => "T&#46; Hosono"
                            5 => "T&#46; Maeno"
                            6 => "T&#46; Suga"
                            7 => "J&#46; Sugano"
                            8 => "Y&#46; Shitara"
                            9 => "M&#46; Kurabayashi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Intern Med"
                        "fecha" => "2001"
                        "volumen" => "40"
                        "numero" => "11"
                        "paginaInicial" => "1128"
                        "paginaFinal" => "1131"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11757769"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            43 => array:3 [
              "identificador" => "bib44"
              "etiqueta" => "44&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Manique A&#46; Tuberculose na Mulher &#8211; Aspectos particulares&#46; 39&#46;&#176; Curso de Pneumologia para p&#243;s graduados&#46; Patologia respirat&#243;ria na mulher&#44; que diferen&#231;as&#63; Cl&#237;nica de Pneumologia&#46; FML&#47;HSM&#46; Lisboa 2006&#59; 153-62&#46;"
                ]
              ]
            ]
            44 => array:3 [
              "identificador" => "bib45"
              "etiqueta" => "45&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "World Health Organization&#46; Stop Tuberculosis Guidelines for Social Mobilization&#46; A Human Rights Approach to Tuberculosis&#46; WHO&#47;CDS&#47;STB&#44; 2001&#46;"
                ]
              ]
            ]
            45 => array:3 [
              "identificador" => "bib46"
              "etiqueta" => "46&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberculosis in association with pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "J&#46;T&#46;I&#46; Good"
                            1 => "P&#46;T&#46; Davidson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Obstet Gynecol"
                        "fecha" => "1981"
                        "volumen" => "140"
                        "paginaInicial" => "492"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7246682"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            46 => array:3 [
              "identificador" => "bib47"
              "etiqueta" => "47&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberculosis and Pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "V&#46;K&#46; Arora"
                            1 => "R&#46; Gupta"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Indian Journal of Tuberculosis"
                        "fecha" => "2003"
                        "volumen" => "50"
                        "paginaInicial" => "13"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            47 => array:3 [
              "identificador" => "bib48"
              "etiqueta" => "48&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Programa Nacional da Luta Contra a Tuberculose&#46; Sistema de Vigil&#226;ncia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "F&#46; Antunes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Ponto de situa&#231;&#227;o epidemiol&#243;gica e de desempenho"
                        "fecha" => "2003"
                        "paginaInicial" => "1"
                        "paginaFinal" => "12"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            48 => array:3 [
              "identificador" => "bib49"
              "etiqueta" => "49&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Administra&#231;&#227;o de Sa&#250;de do Norte&#46; Sa&#250;de na Regi&#227;o Norte&#46; Centro regional de sa&#250;de p&#250;blica do norte&#44; Dezembro 2001&#46; Medir para mudar&#46; Tuberculose&#46; Minist&#233;rio da Sa&#250;de&#58; 126-36&#46;"
                ]
              ]
            ]
            49 => array:3 [
              "identificador" => "bib50"
              "etiqueta" => "50&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bases epidemiol&#243;gicas do controlo da tuberculose"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "Rieder"
                            1 => "L&#46; Hans"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:2 [
                        "tituloSerie" => "Direc&#231;&#227;o Geral de Sa&#250;de"
                        "fecha" => "2001"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            50 => array:3 [
              "identificador" => "bib51"
              "etiqueta" => "51&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Manual de Pneumologia&#46; 2002&#46;Sociedade Brasileira PT&#46; Pneumopatias na gesta&#231;&#227;o&#58; 371-8&#46;"
                ]
              ]
            ]
            51 => array:3 [
              "identificador" => "bib52"
              "etiqueta" => "52&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Quimioterapia antituberculosa&#46; Tratado de Pneumologia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;F&#46; Telhada"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:6 [
                        "editores" => "R&#46;Sotto- Mayor"
                        "paginaInicial" => "711"
                        "paginaFinal" => "764"
                        "serieVolumen" => "I"
                        "serieTitulo" => "Maria Jo&#227;o Marques Gomes"
                        "serieFecha" => "2003"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            52 => array:3 [
              "identificador" => "bib53"
              "etiqueta" => "53&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Pestana E&#44; Pina J&#46; A Tuberculose em grupos epidemiol&#243;gicos Particulares&#46; Tuberculose na Viragem do Mil&#233;nio&#46; Lidel &#8211; Edic&#245;es T&#233;cnicas&#44; Lda&#46; 501-503&#46;"
                ]
              ]
            ]
            53 => array:3 [
              "identificador" => "bib54"
              "etiqueta" => "54&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Preliminary study of the association of tuberculosis and pregnancy&#58; about 9 cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:11 [
                            0 => "N&#46;O&#46; Toure"
                            1 => "Y&#46; Dia"
                            2 => "A&#46; Diatta"
                            3 => "C&#46;M&#46; Ndiaye"
                            4 => "B&#46;A&#46; Sah"
                            5 => "A&#46; Niang"
                            6 => "N&#46; Fall"
                            7 => "M&#46; Kane"
                            8 => "F&#46; Mbaye"
                            9 => "A&#46; Cisse"
                            10 => "A&#46;A&#46; Hane"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Dakar Med"
                        "fecha" => "2004"
                        "volumen" => "49"
                        "numero" => "3"
                        "paginaInicial" => "192"
                        "paginaFinal" => "195"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15776617"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            54 => array:3 [
              "identificador" => "bib55"
              "etiqueta" => "55&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Gomes MC&#44; Freitas MG&#44; Ponce P&#46; Tuberculose pulmonar e extra pulmonar&#46; Manual de Terap&#234;utica M&#233;dica 1&#46; Lidel &#8211; Edi&#231;&#245;es T&#233;cnicas&#44; Lda&#46; 2002&#58; 12-21&#46;"
                ]
              ]
            ]
            55 => array:3 [
              "identificador" => "bib56"
              "etiqueta" => "56&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "World Health Organization information&#46; TB is single biggest killer of young women&#46; Press release WHO&#47;40&#46; 1998&#46;"
                ]
              ]
            ]
            56 => array:3 [
              "identificador" => "bib57"
              "etiqueta" => "57&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Treatment of tuberculosis&#58; Guidelines for National Programme&#58; WHO&#47;CDS&#47;TB 2003&#46;313&#46;Geneve&#58; World Health Organization&#44; 2003&#46;"
                ]
              ]
            ]
            57 => array:3 [
              "identificador" => "bib58"
              "etiqueta" => "58&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Treatment of tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "American Thoracic Society&#47;Centers of Disease Control and Prevention&#47;infections Diseases Society of America"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Respir Crit Med"
                        "fecha" => "2003"
                        "volumen" => "167"
                        "paginaInicial" => "603"
                        "paginaFinal" => "662"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            58 => array:3 [
              "identificador" => "bib59"
              "etiqueta" => "59&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "British HIV Association Guidelines for TB&#47;HIV infection&#46; Feb 2005&#46;"
                ]
              ]
            ]
            59 => array:3 [
              "identificador" => "bib60"
              "etiqueta" => "60&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Centers for Diseases Control and Prevention &#40;CDC&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Congenital pulmonary tuberculosis associated with maternal cerebral tuberculois Florida&#44; 2002"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "MMWR Morb Mortal Wkly Rep"
                        "fecha" => "2005"
                        "volumen" => "54"
                        "numero" => "10"
                        "paginaInicial" => "249"
                        "paginaFinal" => "250"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15772585"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            60 => array:3 [
              "identificador" => "bib61"
              "etiqueta" => "61&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Abordagem do adulto 39&#46; &#176; Curso de Pneumologia para p&#243;s-graduados&#46; Patologia respirat&#243;ria na mulher&#44; que diferen&#231;as&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46; Azevedo"
                            1 => "Qu&#237;stica Fibrose"
                          ]
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Cl&#237;nica de Pneumologia&#58; FML&#47;HSM&#46; Lisboa"
                        "fecha" => "2006"
                        "paginaInicial" => "115"
                        "paginaFinal" => "117"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            61 => array:3 [
              "identificador" => "bib62"
              "etiqueta" => "62&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Stuart E&#46; Pregnancy and Cystic Fibrosis&#46; Cystic Fibrosis Trust 2002&#46; First published in CF Today Autumn 2002&#46;"
                ]
              ]
            ]
            62 => array:3 [
              "identificador" => "bib63"
              "etiqueta" => "63&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The psychological and social implications of caring for the pregnant patient and newborn with cystic fibrosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46;M&#46; Connors"
                            1 => "M&#46;M&#46; Ulles"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "J Perinat Neonatal Nurs"
                        "fecha" => "2005"
                        "volumen" => "19"
                        "numero" => "4"
                        "paginaInicial" => "301"
                        "paginaFinal" => "315"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16292132"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            63 => array:3 [
              "identificador" => "bib64"
              "etiqueta" => "64&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence and outcome of pregnancy in Norwegian and Swedish Women with cystic fibrosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "I&#46; Odegaard"
                            1 => "B&#46; Stray-Pedersen"
                            2 => "K&#46; Hallberg"
                            3 => "O&#46;C&#46; Haanaes"
                            4 => "O&#46;T&#46; Storrosten"
                            5 => "M&#46; Johannesson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Acta Obstet Gynecol Scand"
                        "fecha" => "2002"
                        "volumen" => "81"
                        "numero" => "8"
                        "paginaInicial" => "693"
                        "paginaFinal" => "697"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12174151"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            64 => array:3 [
              "identificador" => "bib65"
              "etiqueta" => "65&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Impact of pregnancy on women with cystic fibrosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "A&#46;H&#46; Mc Mullen"
                            1 => "D&#46;J&#46; Pasta"
                            2 => "P&#46;D&#46; Frederick"
                            3 => "M&#46;W&#46; Konstan"
                            4 => "W&#46;J&#46; Morgan"
                            5 => "M&#46;S&#46; Schechter"
                            6 => "J&#46;S&#46; Wagener"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.129.3.706"
                      "Revista" => array:7 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2006"
                        "volumen" => "129"
                        "numero" => "3"
                        "paginaInicial" => "706"
                        "paginaFinal" => "711"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16537871"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            65 => array:3 [
              "identificador" => "bib66"
              "etiqueta" => "66&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cystic Fibrosis Adult Care"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;R&#46; Yankaskas"
                            1 => "B&#46;C&#46; Marshall"
                            2 => "J&#46;D&#46; Sulfian"
                            3 => "R&#46;H&#46; Simon"
                            4 => "D&#46; Rodman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2004"
                        "volumen" => "125"
                        "paginaInicial" => "1S"
                        "paginaFinal" => "39S"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14734689"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            66 => array:3 [
              "identificador" => "bib67"
              "etiqueta" => "67&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pregnancies and Outcome in Women with Cystic Fibrosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:11 [
                            0 => "B&#46; Asher"
                            1 => "M&#46; Dulitzki"
                            2 => "O&#46; Efrati"
                            3 => "A&#46; Augarten"
                            4 => "A&#46; Szeinberg"
                            5 => "N&#46; Reichert"
                            6 => "D&#46; Modan"
                            7 => "B&#46; Weiss"
                            8 => "M&#46; Miller"
                            9 => "D&#46; Katzanelson"
                            10 => "Y&#46; Yahav"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Is Med Assoc J"
                        "fecha" => "2005"
                        "volumen" => "7"
                        "numero" => "2"
                        "paginaInicial" => "95"
                        "paginaFinal" => "98"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            67 => array:3 [
              "identificador" => "bib68"
              "etiqueta" => "68&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effect of pregnancy on survival in women with cystic fibrosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46;H&#46; Goss"
                            1 => "G&#46;D&#46; Rubenfeld"
                            2 => "K&#46; Otto"
                            3 => "M&#46;L&#46; Aitken"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2003"
                        "volumen" => "124"
                        "numero" => "4"
                        "paginaInicial" => "460"
                        "paginaFinal" => "468"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            68 => array:3 [
              "identificador" => "bib69"
              "etiqueta" => "69&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cystic Fibrosis and pregnancy&#58; report of twin pregnancy and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46; Prenaut"
                            1 => "P&#46; Audra"
                            2 => "C&#46; Mossan"
                            3 => "P&#46; Gaucherand"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Gynecol Obstet Biol Reprod &#40;Paris&#41;"
                        "fecha" => "2005"
                        "volumen" => "34"
                        "numero" => "7 pt"
                        "paginaInicial" => "716"
                        "paginaFinal" => "720"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            69 => array:3 [
              "identificador" => "bib70"
              "etiqueta" => "70&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effect of pregnancy on survival in women with cystic fibrosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46;H&#46; Goss"
                            1 => "G&#46;D&#46; Rubenfeld"
                            2 => "K&#46; Otto"
                            3 => "M&#46;L&#46; Aitken"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2003"
                        "volumen" => "124"
                        "paginaInicial" => "1460"
                        "paginaFinal" => "1467"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14555580"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            70 => array:3 [
              "identificador" => "bib71"
              "etiqueta" => "71&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Management of parturient with respiratory failure secondary to cystic fibrosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;J&#46; Cameron"
                            1 => "T&#46;A&#46; Skinner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Anaestesia"
                        "fecha" => "2005"
                        "volumen" => "60"
                        "numero" => "1"
                        "paginaInicial" => "77"
                        "paginaFinal" => "80"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            71 => array:3 [
              "identificador" => "bib72"
              "etiqueta" => "72&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "O tabagismo&#44; uma conquista feminina&#46; O tabagismo&#44; da depend&#234;ncia &#224; abstin&#234;ncia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Y&#46; Martinet"
                            1 => "A&#46; Bohadana"
                            2 => "S&#46; Toussaint"
                            3 => "N&#46; Wirth"
                            4 => "C&#46; Th&#233;venin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Climepsi Editores"
                        "fecha" => "2003"
                        "volumen" => "5"
                        "paginaInicial" => "193"
                        "paginaFinal" => "216"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            72 => array:3 [
              "identificador" => "bib73"
              "etiqueta" => "73&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pharmacotherapy for smoking cessation during pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "N&#46;L&#46; Benowitz"
                            1 => "D&#46;A&#46; Dempsey"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nicotine e Tabacco Research"
                        "fecha" => "2004"
                        "volumen" => "6"
                        "numero" => "suppl 2"
                        "paginaInicial" => "S189"
                        "paginaFinal" => "S202"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            73 => array:3 [
              "identificador" => "bib74"
              "etiqueta" => "74&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Why women are more susceptible&#59; how treatment should differ&#46; The Rising Epidemic of COPD in Women"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "T&#46;L&#46; Petty"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Women&#39;s Health in Primary Care"
                        "fecha" => "1999"
                        "volumen" => "2"
                        "numero" => "12"
                        "paginaInicial" => "942"
                        "paginaFinal" => "953"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            74 => array:3 [
              "identificador" => "bib75"
              "etiqueta" => "75&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lung cancer in women&#46; Analysis of the national Surveillance&#44; Epidemiology&#44; and End Results database"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "B&#46;J&#46; Fu"
                            1 => "Y&#46;T&#46; Kau"
                            2 => "R&#46;K&#46; Severson"
                            3 => "G&#46;P&#46; Kalemkerian"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.127.2.630"
                      "Revista" => array:5 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2005"
                        "volumen" => "127"
                        "numero" => "3"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15706006"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            75 => array:3 [
              "identificador" => "bib76"
              "etiqueta" => "76&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cancer statistics"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Jemal"
                            1 => "A&#46; Thomas"
                            2 => "T&#46; Murray"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "CA Cancer J Clin"
                        "fecha" => "2002"
                        "volumen" => "52"
                        "paginaInicial" => "23"
                        "paginaFinal" => "47"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11814064"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            76 => array:3 [
              "identificador" => "bib77"
              "etiqueta" => "77&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lung Cancer during pregnancy involving the products of conception and a review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "C&#46; Jackisch"
                            1 => "L&#46; Frank"
                            2 => "A&#46; Schwenkhagen"
                            3 => "K&#46; Brigitta"
                            4 => "K&#46;W&#46; Schimid"
                            5 => "P&#46;G&#46; Schneider"
                            6 => "H&#46; Wolfgang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00404-002-0356-x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Gynecol Obstet"
                        "fecha" => "2003"
                        "volumen" => "268"
                        "paginaInicial" => "69"
                        "paginaFinal" => "77"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12768292"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            77 => array:3 [
              "identificador" => "bib78"
              "etiqueta" => "78&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Maternal pulmonary adenocarcinoma metastatic to the fetus&#58; first recorded case report and literature review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;M&#46; Walker"
                            1 => "J&#46;F&#46; Reinisch"
                            2 => "H&#46;L&#46; Monforte"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Pediatr Pathol Mol Med"
                        "fecha" => "2002"
                        "volumen" => "21"
                        "numero" => "1"
                        "paginaInicial" => "57"
                        "paginaFinal" => "69"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11858176"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            78 => array:3 [
              "identificador" => "bib79"
              "etiqueta" => "79&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Intracranial metastasis via transplacental &#40;vertical&#41; transmission of maternal small cell lung cancer to fetus&#58; CT and MRI findings"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46; Teksam"
                            1 => "A&#46; McKinney"
                            2 => "J&#46; Short"
                            3 => "S&#46;O&#46; Casey"
                            4 => "C&#46;L&#46; Truwit"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Acta Radiol"
                        "fecha" => "2004"
                        "volumen" => "45"
                        "numero" => "5"
                        "paginaInicial" => "577"
                        "paginaFinal" => "579"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15515522"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            79 => array:3 [
              "identificador" => "bib80"
              "etiqueta" => "80&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chemotherapy for a patient with advanced non-small-cell lung cancer during pregnancy&#58; a case report and a review of chemotherapy treatment during pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "P&#46;A&#46; Janne"
                            1 => "D&#46; Rodriguez Thompson"
                            2 => "D&#46;R&#46; Metcalf"
                            3 => "S&#46;J&#46; Swanson"
                            4 => "H&#46;A&#46; Greisman"
                            5 => "L&#46;W&#46; Haug"
                            6 => "B&#46;E&#46; Johnson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "55371"
                      "Revista" => array:7 [
                        "tituloSerie" => "Oncology"
                        "fecha" => "2001"
                        "volumen" => "61"
                        "numero" => "3"
                        "paginaInicial" => "175"
                        "paginaFinal" => "183"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11574771"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            80 => array:3 [
              "identificador" => "bib81"
              "etiqueta" => "81&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Management of respiratory deterioration in a pregnant patient with severe kyphoscoliosis by non-invasive positive pressure ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "C&#46;M&#46; Kahler"
                            1 => "B&#46; Hogl"
                            2 => "R&#46; Habeler"
                            3 => "C&#46; Brezinka"
                            4 => "J&#46; Hamacher"
                            5 => "A&#46; Dienstl"
                            6 => "C&#46; Prior"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Wien Klin Wochenschr"
                        "fecha" => "2002"
                        "volumen" => "114"
                        "numero" => "19&#8211;20"
                        "paginaInicial" => "874"
                        "paginaFinal" => "877"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12503480"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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Vol. 13. Issue 2.
Pages 213-237 (March - April 2007)
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Vol. 13. Issue 2.
Pages 213-237 (March - April 2007)
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Pulmão e gravidez
Pregnancy and lungs
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928
Inês A C Gonçalves Marcos1, João Valença Rodrigues2, Renato Sotto-Mayor3
1 Interna do 5.° ano de Pneumologia, Serviço de Pneumologia, Hospital de Santa Maria, Lisboa
2 Assistente Graduado de Pneumologia, Serviço de Pneumologia, Hospital de Santa Maria, Lisboa
3 Director do Serviço de Pneumologia, Serviço de Pneumologia, Hospital de Santa Maria, Lisboa
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Resumo

A patologia respiratória é relativamente frequente durante a gravidez. Um terço das grávidas sofrem exacerbação da asma. O tromboembolismo pulmonar é cerca de 5 vezes mais frequente na gravidez. As pneumonias bacterianas, virais e fúngicas são mal toleradas pela grávida, provocando significativa morbilidade materno-fetal, insuficiência respiratória, baixo peso ao nascer ou prematuridade. A tuberculose, se não for tratada, pode aumentar em 4 vezes a mortalidade materna e em 9 vezes o parto pré-termo. A gravidez está contra-indicada em mulheres com fibrose quística e função pulmonar grave. Apesar dos progressos terapêuticos, a hipertensão pulmonar continua a estar associada a valores superiores a 30% de morbilidade e mortalidade materno-fetal. Aproximadamente 1 em 1000–1500 gravidezes é complicada por neoplasia maligna materna. O cancro do pulmão nas grávidas coloca desafios terapêuticos importantes devido às elevadas taxas de mortalidade.

Palavras-chave:
Pulmão
gravidez
alterações fisiológicas
complicações pulmonares
Abstract

Respiratory pathology can be relatively frequent during pregnancy. One third of pregnant woman may experience worsening of their asthma condition. Pulmonary tromboembolism is 5 times more frequent in pregnancy. Bacterial, viral and fungal pneumonias are baddly tolerated during pregnancy, provoking mother-foetal morbidity, respiratory insufficiency, low born-weight or prematurity. Non-treated tuberculosis may increase maternal mortality and preterm birth by 4 and 9 times respectively. Pregnancy is counter-indicated in women with cystic fibrosis and severe pulmonary function. Despite therapeutic progresses already made, pulmonary hypertension is associated to over 30% of mother-foetal morbidity and mortality. Approximately 1 in 1,000-1,500 pregnancies is affected by mother cancer. High rates of lung cancer morbility in women bring new and important challenges to therapy.

Key-words:
Pregnancy
lung
physiological changes
pulmonary complications
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Bibliografia
[1.]
S.H. Soubra, K.K. Guntupalli.
Critical illness in pregnancy: An overview.
Crit Care Med, 33 (2005), pp. S248-S255
[2.]
P. Bhatia, K. Bhatia.
Pregnancy and the lungs.
Postgrad Med J, 76 (2000), pp. 683-689
[3.]
E.R. Yeomans, C. Gilstrap III.
Physiologic Changes in pregnancy and their impact on critical care.
Crit Care Med, 33 (2005), pp. S256-S258
[4.]
Cunningham F, Gant N, Leveno K, Gilstrap L, Hauth J, Wenstrom K. Section XII: Medical and Surgical complications in pregnancy. Williams Obstetrics 21 St edition 2001; 1224-44.
[5.]
K. Spiropoulos, E. Prodromaki, V. Tsapanos.
Effect of Body Position on PaO2 and PaCO2 during pregnancy.
Gynecologic and Obstetric Investigation, 58 (2004),
[6.]
Sat Sharma. Pulmonary disease and pregnancy. www.emedicine.com/med/topic3252.htm. Updated: 2004.
[7.]
R.A. Wise, A.J. Polito, V. Krishnan.
Respiratory physiologic changes in pregnancy.
Immunol Allergy Clin North Am, 26 (2006), pp. 1-12
[8.]
K. Spiropoulos, E. Prodromaki, V Tsapanos.
Effect of body position on PaO2 and PaCO2 during pregnancy.
Gynecologic and Obstetric Investigation, 58 (2004),
[9.]
A. Bier, J.C. Virchow.
Pneumological Disease in Pregnancy.
MMW Fortschr Med, 147 (2005), pp. 32-33
[10.]
E. Murphy, P.G. Gibson, R. Smith, V.L. Clifton.
Asthma during pregnancy: mechanisms and treatment implication.
Eur Respir Journ, 25 (2005), pp. 731-750
[11.]
National Asthma Education and Prevention Program Asthma Pregnancy. Managing Asthma During Pregnancy: Recommendations for Pharmacologic Treatment. Update 2004.
[12.]
V.E. Murphy, V.L. Clifton, P.G. Gibson.
Asthma exacerbations during pregnancy: incidence and association with adverse pregnancy outcomes.
Thorax, 61 (2006), pp. 169-176
[13.]
Brum G. Gravidez-complicações pulmonares. 39.° Curso de Pneumologia para pós-graduados. Patologia respiratória na mulher, que diferenças? Clínica de Pneumologia. FML/HSM. 30 Março a 1 de Abril de 2006; 145-51.
[14.]
Freitas MG, Amaral Marques R, Ponce P. Asma brônquica. Manual de Terapêutica Médica 1. Lidel Edições Técnicas, Lda. 2002; 45-54.
[15.]
S.M. Bates, J.S. Ginsberg.
How we manage venous thromboembolism during pregnancy.
Blood, 100 (2002), pp. 3470-3478
[16.]
A.F. Scarsbrook, A.L. Evans, A.R. Owen, F.V. Gleeson.
Diagnosis of suspected venous thromboembolic disease in pregnancy.
Clin Radiol, 61 (2006), pp. 1-12
[17.]
M. Lisa, L.B. Kathry, M. Susan.
MSc. Sex and gender issues and venous thromboembolism.
Clin Chest Med, 25 (2004), pp. 281-297
[18.]
S. Stone, T.A. Morris.
Pulmonary embolism during and after pregnancy.
Crit Care Med, 33 (2005), pp. S294-S299
[19.]
Monteiro JT. Tromboembolismo pulmonar: Aspectos particulares. 39.° Curso de Pneumologia para pós-graduados. Patologia respiratória na mulher, que diferenças? Clínica de Pneumologia. FML/HSM. Lisboa, 2006; 115-7.
[20.]
T.E. Nolan, R.P. Smith, L.D. Devoe.
Maternal plasma D-dimer levels in normal and complicated pregnancy.
Obstet Gynecol, 81 (1993), pp. 235-238
[21.]
L.K. Tan, M. Swiet.
Management of thromboembolic disease in pregnancy.
Ann Acad Med Singapore, 31 (2002), pp. 311-319
[22.]
E.L. Palmer, J.A. Scott, H.W. Strauss.
Practical Nuclear Medicine.
WB Saunders, (1992),
[23.]
Goldhaber SZ. Pulmonary Embolism. Medical Progress. 339(2):93-104.
[24.]
E. Trukhacheva, M. Scharff, M. Gardner, N. Lakkis.
Massive pulmonary embolism in pregnancy treated with tissue plasminogen activator.
Obstet Gynecol, 106 (2005), pp. 1156-1158
[25.]
J. Moore, M.R. Baldisseri.
Amniotic fluid embolism.
Crit Care Med, 33 (2005), pp. S279-S284
[26.]
B.M. Marie, A.C. Arroliga, S. Emery.
Exacerbation of underlying pulmonary disease in pregnancy.
Crit Care Med, 33 (2005), pp. S313-S321
[27.]
Martins Correia J. Hipertensão Pulmonar. In: Maria João Marques Gomes, R Sotto-Mayor (eds): Tratado de Pneumologia. Vol II. SPP. 1599-626.
[28.]
D. Bendayan, M. Hold, G. Oron, A. Sagie, L. Eidelman, D. Shitrit, M.R. Kramer.
Pregnancy outcome in patients with pulmonary arterial hypertension Receiving prostacyclin therapy.
Obstetrics and Gynecology, 106 (2005),
[29.]
Mendes AC. Doenças vasculares do pulmão. 39.° Curso de Pneumologia para pós-graduados. Patologia respiratória na mulher, que diferenças? Clínica de Pneumologia. FML/HSM. Lisboa, 2006; 115-7.
[30.]
C.A. Elliot, P. Stewart, V.J. Webster, G.H. Mills, S.P. Hutchinson, E.S. Howarth, F.A. Bu’lock, R.A. Lawson, I.J. Armstrong, D.G. Kiely.
The use of iloprost in early pregnancy in patients with pulmonary arterial hypertension.
Eur Respir Journ, 26 (2005), pp. 168-173
[31.]
Carro-Jiménez EJ, Lopez JE. Primary pulmonary hypertension and pregnancy. Bol Assoc Med PR 97(4):328-33.
[32.]
I. Bildirici, J.B. Shumway.
Intravenous and Inhaled Epoprostenol for primary pulmonary hypertension during pregnancy and delivery.
Obstetrics and Gynecology, 3 (2004),
[33.]
B.M Weiss, O.M. Hess.
Pulmonary vascular disease and pregnancy: current controversies, management strategies perspectives..
Eur Heart J, 21 (2000), pp. 104-115
[34.]
C. Geohas, V.V. McLaughlin.
Successful Management of Pregnancy in a Patient with Eisenmerger Syndrome With Epoprostenol.
Chest, 124 (2003), pp. 1170-1173
[35.]
R.J. Barst, L.J. Rubin, W.A. Long, S. Rich, et al.
A comparison of continuous intravenous Epoprostenol with conventional therapy for primary pulmonary hypertension.
N Eng J Med, 334 (1996), pp. 22-301
[36.]
D.E. Cole, T.L. Taylor, D.M. McCullough, C.T. Shoff, S. Derdak.
Acute respiratory distress syndrome in pregnancy.
Crit Care Med, 33 (2005), pp. S269-S276
[37.]
S. Fatimi, S. Sheikh, S.F. Khan.
Student. Arterio-venous malformation of the lung in pregnancy with massive haemoptysis.
IJTCVS, 21 (2005), pp. 281-282
[38.]
P.S. Ramsey, K.D. Ramin.
Pneumonia in pregnancy.
Obstet Gynecol Clin North Am, (2001), pp. 28
[39.]
W.S. Lim, J.T. Macfarlane, C.L. Colthorpe.
Treatment of community-acquired lower respiratory tract infections during pregnancy.
Am J Respir Med, 2 (2003), pp. 221-233
[40.]
U. Munnur, B. Boisblanc, M.S. Suresh.
Airway problems in pregnancy.
Crit Care Med, 33 (2005), pp. S259-S267
[41.]
Ely JW, Jerome Y, Noelle B. Evaluation of Pregnant Womem Exposed to Respiratory Virus. American Family Physician. American Academy of Family Physicians. 2000.
[42.]
Wheat LJ. Systemic Fungal Infection During Pregnancy. Case Study 2005A.
[43.]
F. Aoki, Y. Sando, S. Tajima, K. Imai, T. Hosono, T. Maeno, T. Suga, J. Sugano, Y. Shitara, M. Kurabayashi.
Invasive Pulmonary Aspergillosis in a Puerperant with Drug induced Agranulocytosis.
Intern Med, 40 (2001), pp. 1128-1131
[44.]
Manique A. Tuberculose na Mulher – Aspectos particulares. 39.° Curso de Pneumologia para pós graduados. Patologia respiratória na mulher, que diferenças? Clínica de Pneumologia. FML/HSM. Lisboa 2006; 153-62.
[45.]
World Health Organization. Stop Tuberculosis Guidelines for Social Mobilization. A Human Rights Approach to Tuberculosis. WHO/CDS/STB, 2001.
[46.]
J.T.I. Good, P.T. Davidson, et al.
Tuberculosis in association with pregnancy.
Am J Obstet Gynecol, 140 (1981), pp. 492
[47.]
V.K. Arora, R. Gupta.
Tuberculosis and Pregnancy.
Indian Journal of Tuberculosis, 50 (2003), pp. 13
[48.]
F. Antunes.
Programa Nacional da Luta Contra a Tuberculose. Sistema de Vigilância.
Ponto de situação epidemiológica e de desempenho, (2003), pp. 1-12
[49.]
Administração de Saúde do Norte. Saúde na Região Norte. Centro regional de saúde pública do norte, Dezembro 2001. Medir para mudar. Tuberculose. Ministério da Saúde: 126-36.
[50.]
Rieder, L. Hans.
Bases epidemiológicas do controlo da tuberculose.
Direcção Geral de Saúde, (2001),
[51.]
Manual de Pneumologia. 2002.Sociedade Brasileira PT. Pneumopatias na gestação: 371-8.
[52.]
M.F. Telhada.
Quimioterapia antituberculosa. Tratado de Pneumologia.
pp. 711-764
[53.]
Pestana E, Pina J. A Tuberculose em grupos epidemiológicos Particulares. Tuberculose na Viragem do Milénio. Lidel – Edicões Técnicas, Lda. 501-503.
[54.]
N.O. Toure, Y. Dia, A. Diatta, C.M. Ndiaye, B.A. Sah, A. Niang, N. Fall, M. Kane, F. Mbaye, A. Cisse, A.A. Hane.
Preliminary study of the association of tuberculosis and pregnancy: about 9 cases.
Dakar Med, 49 (2004), pp. 192-195
[55.]
Gomes MC, Freitas MG, Ponce P. Tuberculose pulmonar e extra pulmonar. Manual de Terapêutica Médica 1. Lidel – Edições Técnicas, Lda. 2002: 12-21.
[56.]
World Health Organization information. TB is single biggest killer of young women. Press release WHO/40. 1998.
[57.]
Treatment of tuberculosis: Guidelines for National Programme: WHO/CDS/TB 2003.313.Geneve: World Health Organization, 2003.
[58.]
American Thoracic Society/Centers of Disease Control and Prevention/infections Diseases Society of America.
Treatment of tuberculosis.
Am J Respir Crit Med, 167 (2003), pp. 603-662
[59.]
British HIV Association Guidelines for TB/HIV infection. Feb 2005.
[60.]
Congenital pulmonary tuberculosis associated with maternal cerebral tuberculois Florida, 2002.
Centers for Diseases Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep, 54 (2005), pp. 249-250
[61.]
P. Azevedo, Quística Fibrose.
Abordagem do adulto 39. ° Curso de Pneumologia para pós-graduados. Patologia respiratória na mulher, que diferenças?.
Clínica de Pneumologia: FML/HSM. Lisboa, (2006), pp. 115-117
[62.]
Stuart E. Pregnancy and Cystic Fibrosis. Cystic Fibrosis Trust 2002. First published in CF Today Autumn 2002.
[63.]
P.M. Connors, M.M. Ulles.
The psychological and social implications of caring for the pregnant patient and newborn with cystic fibrosis.
J Perinat Neonatal Nurs, 19 (2005), pp. 301-315
[64.]
I. Odegaard, B. Stray-Pedersen, K. Hallberg, O.C. Haanaes, O.T. Storrosten, M. Johannesson.
Prevalence and outcome of pregnancy in Norwegian and Swedish Women with cystic fibrosis.
Acta Obstet Gynecol Scand, 81 (2002), pp. 693-697
[65.]
A.H. Mc Mullen, D.J. Pasta, P.D. Frederick, M.W. Konstan, W.J. Morgan, M.S. Schechter, J.S. Wagener.
Impact of pregnancy on women with cystic fibrosis.
Chest, 129 (2006), pp. 706-711
[66.]
J.R. Yankaskas, B.C. Marshall, J.D. Sulfian, R.H. Simon, D. Rodman.
Cystic Fibrosis Adult Care.
Chest, 125 (2004), pp. 1S-39S
[67.]
B. Asher, M. Dulitzki, O. Efrati, A. Augarten, A. Szeinberg, N. Reichert, D. Modan, B. Weiss, M. Miller, D. Katzanelson, Y. Yahav.
Pregnancies and Outcome in Women with Cystic Fibrosis.
Is Med Assoc J, 7 (2005), pp. 95-98
[68.]
C.H. Goss, G.D. Rubenfeld, K. Otto, M.L. Aitken.
The effect of pregnancy on survival in women with cystic fibrosis.
Chest, 124 (2003), pp. 460-468
[69.]
J. Prenaut, P. Audra, C. Mossan, P. Gaucherand.
Cystic Fibrosis and pregnancy: report of twin pregnancy and review of the literature.
J Gynecol Obstet Biol Reprod (Paris), 34 (2005), pp. 716-720
[70.]
C.H. Goss, G.D. Rubenfeld, K. Otto, M.L. Aitken.
The effect of pregnancy on survival in women with cystic fibrosis.
Chest, 124 (2003), pp. 1460-1467
[71.]
A.J. Cameron, T.A. Skinner.
Management of parturient with respiratory failure secondary to cystic fibrosis.
Anaestesia, 60 (2005), pp. 77-80
[72.]
Y. Martinet, A. Bohadana, S. Toussaint, N. Wirth, C. Thévenin.
O tabagismo, uma conquista feminina. O tabagismo, da dependência à abstinência.
Climepsi Editores, 5 (2003), pp. 193-216
[73.]
N.L. Benowitz, D.A. Dempsey.
Pharmacotherapy for smoking cessation during pregnancy.
Nicotine e Tabacco Research, 6 (2004), pp. S189-S202
[74.]
T.L. Petty.
Why women are more susceptible; how treatment should differ. The Rising Epidemic of COPD in Women.
Women's Health in Primary Care, 2 (1999), pp. 942-953
[75.]
B.J. Fu, Y.T. Kau, R.K. Severson, G.P. Kalemkerian.
Lung cancer in women. Analysis of the national Surveillance, Epidemiology, and End Results database.
[76.]
A. Jemal, A. Thomas, T. Murray, et al.
Cancer statistics.
CA Cancer J Clin, 52 (2002), pp. 23-47
[77.]
C. Jackisch, L. Frank, A. Schwenkhagen, K. Brigitta, K.W. Schimid, P.G. Schneider, H. Wolfgang.
Lung Cancer during pregnancy involving the products of conception and a review of the literature.
Arch Gynecol Obstet, 268 (2003), pp. 69-77
[78.]
J.M. Walker, J.F. Reinisch, H.L. Monforte.
Maternal pulmonary adenocarcinoma metastatic to the fetus: first recorded case report and literature review.
Pediatr Pathol Mol Med, 21 (2002), pp. 57-69
[79.]
M. Teksam, A. McKinney, J. Short, S.O. Casey, C.L. Truwit.
Intracranial metastasis via transplacental (vertical) transmission of maternal small cell lung cancer to fetus: CT and MRI findings.
Acta Radiol, 45 (2004), pp. 577-579
[80.]
P.A. Janne, D. Rodriguez Thompson, D.R. Metcalf, S.J. Swanson, H.A. Greisman, L.W. Haug, B.E. Johnson.
Chemotherapy for a patient with advanced non-small-cell lung cancer during pregnancy: a case report and a review of chemotherapy treatment during pregnancy.
Oncology, 61 (2001), pp. 175-183
[81.]
C.M. Kahler, B. Hogl, R. Habeler, C. Brezinka, J. Hamacher, A. Dienstl, C. Prior.
Management of respiratory deterioration in a pregnant patient with severe kyphoscoliosis by non-invasive positive pressure ventilation.
Wien Klin Wochenschr, 114 (2002), pp. 874-877
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