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Vol. 14. Issue 4.
Pages 579-583 (July - August 2008)
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Vol. 14. Issue 4.
Pages 579-583 (July - August 2008)
As Nossas Leituras
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Avaliação dos resultados nos ensaios clínicos na DPOC: Da função pulmonar aos marcadores biológicos
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M. Cazzola1, W. MacNee1, F.J. Martinez1, K.F. Rabe1
1 On behalf of the ATS/ERS TASK Force on outcomes of COPD.
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Resumo

As sociedades científicas respiratórias europeia e americana (ERS e ATS) constituíram um grupo de trabalho sobre a “Avaliação dos resultados nos ensaios clínicos na DPOC: da função pulmonar aos marcadores biológicos” para informar a comunidade de investigadores em DPOC sobre o possível uso e limitações dos resultados obtidos e marcadores usados actualmente na avaliação do impacto da terapêutica farmacológica. Com base na revisão da literatura, este documento aborda diferentes secções que avaliam marcadores e resultados específicos: função pulmonar; resultados centrados no doente; exacerbações; nortalidade; impacto social e económico; exames de imagem; marcadores não pulmonares; mínima diferença clinicamente significativa; marcadores biológicos.

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Copyright © 2008. Sociedade Portuguesa de Pneumologia/SPP
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