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        "titulo" => "Altera&#231;&#245;es ecocardiogr&#225;ficas em doentes asm&#225;ticos"
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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Asthma is a chronic inflammatory disease which has increased during the last 20 years&#44; putting a strain on medical resources&#44; particularly severe forms of the disease&#46; Treatment in such cases is inhaled corticosteroids and beta agonist drugs that can produce a range of side effects&#46; The aim of this study is to identify echocardiograph abnormalities and correlate them with severity of disease&#46;</p> <span class="elsevierStyleSectionTitle">Methodology</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Eight-seven outpatients were selected at the asthma unit of the Gaffree Guinle University Hospital &#40;HUGG&#41;&#46; Each patient underwent spirometry&#44; electrocardiogram &#40;ECG&#41; and echocardiogram &#40;ECO&#41; during the trial within a month maximum&#46; Echocardiograph abnormalities found related to degree of asthma&#46; Statistical analysis was made by nonparametric tests&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">We found significant differences &#40;p<span class="elsevierStyleHsp" style=""></span>&#8804;<span class="elsevierStyleHsp" style=""></span>0&#46;05&#41; for age&#44; disease duration and haemoglobin saturation &#40;SaO<span class="elsevierStyleInf">2</span>&#41; between the moderate and severe groups&#46; In the sample a high prevalence of tricuspid insufficiency &#40;41&#46;4&#37;&#41; was identified&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">ECO identified a series of abnormalities that were not always dependent on severity of disease&#46; ECO can identify pulmonary hypertension through calculation of mean pressure of the pulmonary artery&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introdu&#231;&#227;o</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">A asma &#233; uma doen&#231;a inflamat&#243;ria cr&#243;nica cuja preval&#234;ncia vem aumentando nos &#250;ltimos 20 anos&#46; Demanda grande utiliza&#231;&#227;o de recursos&#44; principalmente no grupo grave&#46; Neste&#44; h&#225; consumo cr&#243;nico de cortic&#243;ides inalat&#243;rios e de &#946;2-agonistas&#44; que podem produzir uma s&#233;rie de problemas&#46; O objectivo deste trabalho &#233; o de rastrear as altera&#231;&#245;es electro e ecocardiogr&#225;ficas e relacion&#225;-las ao grau da asma&#46;</p> <span class="elsevierStyleSectionTitle">Metodologia</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Selecion&#225;mos 87 doentes do ambulat&#243;rio de asma do HUGG&#44; que&#44; por rotina&#44; possuem uma espirografia&#44; um eletrocardiograma &#40;ECG&#41; e um ecocardiograma &#40;ECO&#41; feitos com um intervalo m&#225;ximo de um m&#234;s&#46; As altera&#231;&#245;es ecocardiogr&#225;ficas encontradas foram relacionadas com o grau da asma&#46; Foram usadas estat&#237;sticas n&#227;o param&#233;tricas para essas compara&#231;&#245;es&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Encontr&#225;mos diferen&#231;as significativas &#40;p<span class="elsevierStyleHsp" style=""></span>&#8804;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41; quanto &#224; idade&#44; tempo de asma e satura&#231;&#227;o da hemoglobina &#40;SaO<span class="elsevierStyleInf">2</span>&#41; entre os grupos leve e grave&#46; Na amostra&#44; foi identificada alta preval&#234;ncia de insufici&#234;ncia tric&#250;spide &#40;41&#44;4&#37;&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclus&#245;es</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">O ECO identificou uma s&#233;rie de anormalidades&#44; dependentes ou n&#227;o da gravidade da asma&#46; O ECO pode identificar a hipertens&#227;o arterial pulmonar&#44; pelo c&#225;lculo da press&#227;o m&#233;dia da art&#233;ria pulmonar&#46;</p>"
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Vol. 14. Issue 3.
Pages 363-377 (May - June 2008)
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Vol. 14. Issue 3.
Pages 363-377 (May - June 2008)
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Echocardiograph alterations in asthma patients
Alterações ecocardiográficas em doentes asmáticos
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André Luís Mancini1, Sonia Regina da Silva Carvalho2, Maria do Carmo Valente de Crasto3, Ricardo Marques Dias4,
Corresponding author
dias.ricardomarques@gmail.com

Corresponding author/Endereço correspondência: Rua Barão da Torre 388/104, Ipanema, Rio de Janeiro, Brasil. CEP 22411.000. Tel: 55 21 22472431.
1 Médico formado pela Universidade Federal do Estado do Rio de Janeiro – UNIRIO. Monitor da disciplina de Iniciação Científica 2 / Doctor trained at Universidade Federal do Estado do Rio de Janeiro – UNIRIO. Teaching Assistant, Iniciação Científica 2
2 Prof. Assistente da Universidade Federal do Estado do Rio de Janeiro – UNIRIO. Mestre em medicina / Assistant Professor, Universidade Federal do Estado do Rio de Janeiro – UNIRIO. MSc, Medicine
3 Prof. Adjunto da Universidade Federal do Estado do Rio de Janeiro – UNIRIO. Doutor em medicina / Adjunct Professor, Universidade Federal do Estado do Rio de Janeiro – UNIRIO. PhD, Medicine
4 Prof. Titular da Universidade Federal do Estado do Rio de Janeiro – UNIRIO. Doutor em medicina / Professor at Universidade Federal do Estado do Rio de Janeiro – UNIRIO. PhD, Medicine
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Abstract
Introduction

Asthma is a chronic inflammatory disease which has increased during the last 20 years, putting a strain on medical resources, particularly severe forms of the disease. Treatment in such cases is inhaled corticosteroids and beta agonist drugs that can produce a range of side effects. The aim of this study is to identify echocardiograph abnormalities and correlate them with severity of disease.

Methodology

Eight-seven outpatients were selected at the asthma unit of the Gaffree Guinle University Hospital (HUGG). Each patient underwent spirometry, electrocardiogram (ECG) and echocardiogram (ECO) during the trial within a month maximum. Echocardiograph abnormalities found related to degree of asthma. Statistical analysis was made by nonparametric tests.

Results

We found significant differences (p0.05) for age, disease duration and haemoglobin saturation (SaO2) between the moderate and severe groups. In the sample a high prevalence of tricuspid insufficiency (41.4%) was identified.

Conclusions

ECO identified a series of abnormalities that were not always dependent on severity of disease. ECO can identify pulmonary hypertension through calculation of mean pressure of the pulmonary artery.

Key-words:
Asthma
electrocardiogram
echocardiogram
Resumo
Introdução

A asma é uma doença inflamatória crónica cuja prevalência vem aumentando nos últimos 20 anos. Demanda grande utilização de recursos, principalmente no grupo grave. Neste, há consumo crónico de corticóides inalatórios e de β2-agonistas, que podem produzir uma série de problemas. O objectivo deste trabalho é o de rastrear as alterações electro e ecocardiográficas e relacioná-las ao grau da asma.

Metodologia

Selecionámos 87 doentes do ambulatório de asma do HUGG, que, por rotina, possuem uma espirografia, um eletrocardiograma (ECG) e um ecocardiograma (ECO) feitos com um intervalo máximo de um mês. As alterações ecocardiográficas encontradas foram relacionadas com o grau da asma. Foram usadas estatísticas não paramétricas para essas comparações.

Resultados

Encontrámos diferenças significativas (p0,05) quanto à idade, tempo de asma e saturação da hemoglobina (SaO2) entre os grupos leve e grave. Na amostra, foi identificada alta prevalência de insuficiência tricúspide (41,4%).

Conclusões

O ECO identificou uma série de anormalidades, dependentes ou não da gravidade da asma. O ECO pode identificar a hipertensão arterial pulmonar, pelo cálculo da pressão média da artéria pulmonar.

Palavras-chave:
Asma
ecocardiograma
hipertensão arterial pulmonar
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Trabalho realizado no Hospital Universitário Gaffrée e Guinle da Universidade Federal do Estado do Rio de Janeiro – UNIRIO / Study undertaken at Hospital Universitário Gaffrée e Guinle, Universidade Federal do Estado do Rio de Janeiro – UNIRIO

Copyright © 2008. Sociedade Portuguesa de Pneumologia
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